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(DIFLUOROMETHOXY)BENZENE

Product Name
(DIFLUOROMETHOXY)BENZENE
CAS No.
458-92-4
Chemical Name
(DIFLUOROMETHOXY)BENZENE
Synonyms
A,A-DIFLUOROANISOLE;α,α-Difluoroanisole;1,1-difluoroanisole;alpha-Difluoroanisole;(DIFLUOROMETHOXY)BENZEN;(DIFLUOROMETHOXY)BENZENE;1-(difluoromethoxy)benzene;Difluoromethylphenyl ether;4-(Difluoromethoxy)benzene;ALPHA,ALPHA-DIFLUOROANISOLE
CBNumber
CB7714003
Molecular Formula
C7H6F2O
Formula Weight
144.12
MOL File
458-92-4.mol
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(DIFLUOROMETHOXY)BENZENE Property

Boiling point:
98 °C
Density 
1.2
refractive index 
1.45
Flash point:
43.1±19.0℃
storage temp. 
Sealed in dry,Room Temperature
Specific Gravity
1.200
Appearance
Colorless to light yellow Liquid
λmax
270nm(EtOH)(lit.)
CAS DataBase Reference
458-92-4(CAS DataBase Reference)
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Safety

Hazard Codes 
F
Risk Statements 
10
Safety Statements 
16-24/25-23
RIDADR 
1993
HazardClass 
FLAMMABLE
PackingGroup 
III
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4914
Product name
(Difluoromethoxy)benzene
Purity
>98.0%(GC)
Packaging
5g
Price
$94
Updated
2025/07/31
TCI Chemical
Product number
D4914
Product name
(Difluoromethoxy)benzene
Purity
>98.0%(GC)
Packaging
25g
Price
$281
Updated
2025/07/31
TRC
Product number
D445438
Product name
(Difluoromethoxy)benzene
Packaging
2.5g
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
2607-3-25
Product name
(Difluoromethoxy)benzene
Purity
99%
Packaging
5G
Price
$35
Updated
2021/12/16
SynQuest Laboratories
Product number
2607-3-25
Product name
(Difluoromethoxy)benzene
Purity
99%
Packaging
25g
Price
$95
Updated
2021/12/16
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(DIFLUOROMETHOXY)BENZENE Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Synthesis

75-46-7

108-95-2

458-92-4

At room temperature, 0.28 g (0.003 mol) of phenol, 1.7 g (0.03 mol) of potassium hydroxide (KOH), an appropriate amount of water, and dioxane were added as solvents to a 50 mL round bottom flask. The reaction mixture was heated to 50°C, followed by the passage of trifluoromethane gas bubbling through the reaction solution for 2 hours. After completion of the reaction, the mixture was stirred at 50 °C overnight. The yield of difluoromethoxybenzene was calculated to be 70% by 19F NMR analysis (Figures 1 and 2 show the 19F NMR decoupling and proton coupling spectra of the reaction mixture and the purified difluoromethoxybenzene, respectively), using the 19F NMR integral signal of the HF2CO group as an internal standard.

References

[1] Patent: WO2014/113412, 2014, A1. Location in patent: Page/Page column 4
[2] Journal of Organic Chemistry, 2013, vol. 78, # 17, p. 8904 - 8908

(DIFLUOROMETHOXY)BENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (DIFLUOROMETHOXY)BENZENE manufacturers

Career Henan Chemical Co
Product
(DIFLUOROMETHOXY)BENZENE 458-92-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-08

458-92-4, (DIFLUOROMETHOXY)BENZENERelated Search:

3-(1,1,2,2-TETRAFLUOROETHOXY)BENZALDEHYDE 3-(Trifluoromethoxy)bromobenzene 4-(Trifluoromethoxy)benzyl alcohol 4-(2-CHLORO-1,1,2-TRIFLUORO-ETHOXY)-PHENYLAMINE FCCP 4-(Trifluoromethoxy)nitrobenzene 2,3-Dihydro-2,2-dimethyl-7-benzofuranol 1-Bromo-4-(trifluoromethoxy)benzene 2-(Trifluoromethoxy)aniline 4-(Trifluoromethoxy)benzoic acid 4-(Trifluoromethoxy)chlorobenzene 4-(Trifluoromethoxy)fluorobenzene (Trifluoromethoxy)benzene 2-(Trifluoromethoxy)bromobenzene 4-(DIFLUOROMETHOXY) BENZENE SULFONIC CHLORIDE,4-(difluoromethoxy)benzene-1-sulfonyl chloride 2-(DIFLUOROMETHOXY)BENZYL BROMIDE 1-BROMO-4-(DIFLUOROMETHOXY)BENZENE 97%,1-BROMO-4-(DIFLUOROMETHOXY)BENZENE 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

  • α,α-Difluoroanisole
  • A,A-DIFLUOROANISOLE
  • alpha-Difluoroanisole
  • (Difluoromethyl)phenyl ether
  • Difluoromethyl(phenyl) ether
  • Difluoromethylphenyl ether
  • Phenyl(difluoromethyl) ether
  • alpha,alpha-Difluoroanisole, Difluoromethyl phenyl ether
  • 1-(difluoromethoxy)benzene
  • (DIFLUOROMETHOXY)BENZENE
  • ALPHA,ALPHA-DIFLUOROANISOLE
  • 1,1-difluoroanisole
  • alpha,alpha-Difluoroanisole,98+%
  • Benzene, (difluoromethoxy)-
  • 4-(Difluoromethoxy)benzene
  • (DIFLUOROMETHOXY)BENZEN
  • 458-92-4