ISOQUINOLINE-5-CARBOXYLIC ACID
- Product Name
- ISOQUINOLINE-5-CARBOXYLIC ACID
- CAS No.
- 27810-64-6
- Chemical Name
- ISOQUINOLINE-5-CARBOXYLIC ACID
- Synonyms
- ine-5-carboxyL;RARECHEM AL BE 1523;5-Carboxyisoquinoline;5-Isoquinolinecarboxylicaci;5-isoquinolinecarboxylic acid;ISOQUINOLINE-5-CARBOXYLIC ACID;Isoquinoline-5-carboxylicacid,96%;ISOQUINOLINE-5-CARBOXYLIC ACID ISO 9001：2015 REACH;5-Carboxyisoquinoline, 2-Azanaphthalene-5-carboxylic acid
- CBNumber
- CB7720604
- Molecular Formula
- C10H7NO2
- Formula Weight
- 173.17
- MOL File
- 27810-64-6.mol
ISOQUINOLINE-5-CARBOXYLIC ACID Property
- Melting point:
- 278-281°C
- Boiling point:
- 60-62°C 11mm
- Density
- 1.339±0.06 g/cm3(Predicted)
- Flash point:
- 60-62°C/11mm
- storage temp.
- 2-8°C(protect from light)
- pka
- 1.21±0.10(Predicted)
- form
- solid
- Appearance
- White to off-white Solid
- BRN
- 129180
- CAS DataBase Reference
- 27810-64-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-36-22
- Safety Statements
- 26-36/37/39-22
- WGK Germany
- 3
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 722626
- Product name
- Isoquinoline-5-carboxylic acid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $51.52
- Updated
- 2025/07/31
- Product number
- I918013
- Product name
- Isoquinoline-5-carboxylic acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR8925
- Product name
- Isoquinoline-5-carboxylic acid
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 4H21-1-B2
- Product name
- Isoquinoline-5-carboxylic acid
- Packaging
- 250mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- I11324
- Product name
- Isoquinoline-5-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
ISOQUINOLINE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
Isoquinoline-5-carboxylic acid is an isoquinoline derivative. This group of substances can be used as raw materials for organic synthesis in the preparation of other heterocyclic compounds or pharmaceutical products. Studies have shown that its derivative isoquinoline-3-carboxylic acid (IQ3CA) has antimicrobial activity and is a lead compound with antimicrobial properties for plant diseases[1].
Synthesis
27655-41-0
27810-64-6
The general procedure for the synthesis of isoquinoline-5-carboxylic acid from 5-cyanoisoquinoline was as follows: isoquinoline-5-carbonitrile (6 g, 38.62 mmol) prepared in step (1) was mixed with distilled water (90 mL) and stirred until homogeneous. Concentrated hydrochloric acid solution (15 mL) was slowly added to the reaction system, followed by heating the reaction mixture to 100 °C and continuous stirring for 6 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 5~6 by dropwise addition of N,N-diisopropylethylamine (DIPEA, ca. 40 mL).The resulting suspension was continued to be stirred at room temperature for 3 hr, followed by diafiltration. The collected solid product was dried in an oven at 50 °C to give final isoquinoline-5-carboxylic acid (5.6 g, 84% yield). Mass spectrum (ESI+, m/z): 174 [M+H]+.
References
[1] XU Z, DING H, XIN F, et al. Antibacterial Activity and Possibly Made of Action of Isoquinoline-3-Carboxylic Acid[J]. Natural Product Communications, 2024. DOI:10.1177/1934578x241226562.
ISOQUINOLINE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
ISOQUINOLINE-5-CARBOXYLIC ACID Suppliers
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from ISOQUINOLINE-5-CARBOXYLIC ACID manufacturers
- Product
- ISOQUINOLINE-5-CARBOXYLIC ACID 27810-64-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26