ChemicalBook > CAS DataBase List > Indole-2-carboxylic acid

Indole-2-carboxylic acid

Product Name
Indole-2-carboxylic acid
CAS No.
1477-50-5
Chemical Name
Indole-2-carboxylic acid
Synonyms
1H-INDOLE-2-CARBOXYLIC ACID;2-INDOLECARBOXYLIC ACID;NSC 16598;e-2-carboxyL;AKOS JY2082713;2-CARBOXYINDOLE;Indol-2-carbonsure;Indole-2-carboxylic;2-Carboxy-1H-indole;TIMTEC-BB SBB003953
CBNumber
CB7728231
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
1477-50-5.mol
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Indole-2-carboxylic acid Property

Melting point:
202-206 °C(lit.)
Boiling point:
287.44°C (rough estimate)
Density 
1.2480 (rough estimate)
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in clear yellow solution 5% in ethanol, dimethyl sulfoxide and methanol.
pka
4.44±0.30(Predicted)
form 
Crystalline Powder or Crystals
color 
Off-white to yellow to brown
BRN 
124132
CAS DataBase Reference
1477-50-5(CAS DataBase Reference)
NIST Chemistry Reference
Indole-2-carboxylic acid(1477-50-5)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-21/22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NK7882812
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I5109
Product name
Indole-2-carboxylic acid
Purity
98%
Packaging
5g
Price
$112
Updated
2024/03/01
Sigma-Aldrich
Product number
I5109
Product name
Indole-2-carboxylic acid
Purity
98%
Packaging
10g
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
I0332
Product name
Indole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
I0332
Product name
Indole-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$37
Updated
2024/03/01
Alfa Aesar
Product number
A18690
Product name
Indole-2-carboxylic acid, 98+%
Packaging
10g
Price
$52.8
Updated
2022/04/27
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Indole-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Powder

Uses

• ;Reactant for total synthesis of (±)-dibromophakellin and analogs1• ;Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine2• ;Reactant for stereoselective preparation of renieramycin G analogs3• ;Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization4• ;Reactant for Pd-catalyzed cyclization5• ;Reactant for preparation of N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(

Uses

Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N?-(pentane)diylbis[indolecarboxamide] and N,N?-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

Definition

ChEBI: Indole-2-carboxylic acid is an indolyl carboxylic acid.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 7961, 1992 DOI: 10.1016/S0040-4039(00)74789-7

Indole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Indole-3-carboxylic acid

Preparation Products

3-Indolepropionic acid Indoline-2-carboxylic acid Methyl indole-2-carboxylate
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View Lastest Price from Indole-2-carboxylic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
10 ton
Release date
2021-07-27
Hebei Chuanghai Biotechnology Co,.LTD
Product
Indole-2-carboxylic acid 1477-50-5
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20

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