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5-Hydroxy-2-nitrobenzoic acid

Product Name
5-Hydroxy-2-nitrobenzoic acid
CAS No.
610-37-7
Chemical Name
5-Hydroxy-2-nitrobenzoic acid
Synonyms
RARECHEM AL BE 0679;3-carboxy-4-nitrophenol;5-Hydroxy-2-nitrobenzoic;5-hydroxy-2-nitro-benzoicaci;5-HYDROXY-2-NITROBENZOIC ACID;2-Nitro-5-hydroxybenzoic acid;3-Hydroxy-6-nitro benzoic acid;5-Hydroxy-2-nitrobenzoicAcid>Benzoic acid, 5-hydroxy-2-nitro-;5-Hydroxy-2-nitrobenzoic acid, tech
CBNumber
CB7736391
Molecular Formula
C7H5NO5
Formula Weight
183.12
MOL File
610-37-7.mol
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5-Hydroxy-2-nitrobenzoic acid Property

Melting point:
170-171°C
Boiling point:
455.0±40.0 °C(Predicted)
Density 
1.631
RTECS 
DH2528250
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
2.06±0.25(Predicted)
color 
White to Yellow to Green
CAS DataBase Reference
610-37-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
Hazard Note 
Irritant
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
H1321
Product name
5-Hydroxy-2-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$60
Updated
2025/07/31
TCI Chemical
Product number
H1321
Product name
5-Hydroxy-2-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$176
Updated
2025/07/31
TRC
Product number
H950848
Product name
5-Hydroxy-2-nitrobenzoic Acid
Packaging
1g
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR27506
Product name
5-Hydroxy-2-nitrobenzoic Acid
Packaging
10g
Price
$86
Updated
2021/12/16
SynQuest Laboratories
Product number
4654-1-V3
Product name
5-Hydroxy-2-nitrobenzoic acid
Packaging
10g
Price
$95
Updated
2021/12/16
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5-Hydroxy-2-nitrobenzoic acid Chemical Properties,Usage,Production

Uses

5-Hydroxy-2-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.

Synthesis

2516-95-2

610-37-7

General procedure for the synthesis of 2-nitro-5-hydroxybenzoic acid from 5-chloro-2-nitrobenzoic acid: 5-chloro-2-nitrobenzoic acid (32.00 g, 0.159 mol) was dissolved in 15% aqueous sodium hydroxide solution and reacted at reflux under nitrogen protection for 72 hours. After completion of the reaction, the pH of the reaction solution was adjusted to 1.0 with dilute hydrochloric acid and then extracted with ethyl acetate. The ethyl acetate extracts were combined and dried with anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give 28.05 g of 2-nitro-5-hydroxybenzoic acid in 96.5% yield.

References

[1] Chemistry - A European Journal, 2013, vol. 19, # 43, p. 14654 - 14664
[2] Patent: CN106478548, 2017, A. Location in patent: Paragraph 0019-0020; 0035-0036; 0051-0052; 0067-0068
[3] Patent: US2017/158680, 2017, A1. Location in patent: Paragraph 0330; 0331; 0332
[4] Patent: WO2003/97641, 2003, A2. Location in patent: Page/Page column 63
[5] Patent: US4348396, 1982, A

5-Hydroxy-2-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Hydroxy-2-nitrobenzoic acid Suppliers

Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
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View Lastest Price from 5-Hydroxy-2-nitrobenzoic acid manufacturers

Honest Joy Holdings Limited
Product
5-Hydroxy-2-nitrobenzoic acid 610-37-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5%
Supply Ability
100 tons
Release date
2022-02-21
Career Henan Chemical Co
Product
5-Hydroxy-2-nitrobenzoic acid 610-37-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-05

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