ChemicalBook > CAS DataBase List > 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE

2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE

Product Name
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
CAS No.
36082-45-8
Chemical Name
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
Synonyms
5-bromo-4-methoxypyrimidin-2-amine;2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE;2-Pyrimidinamine, 5-bromo-4-methoxy-;5-bromo-4-methoxypyrimidine-2-ylamine;Pyrimidine, 2-amino-5-bromo-4-methoxy-;2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE ISO 9001:2015 REACH
CBNumber
CB7739963
Molecular Formula
C5H6BrN3O
Formula Weight
204.02
MOL File
36082-45-8.mol
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2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Property

Melting point:
118℃
Boiling point:
364.8±45.0 °C(Predicted)
Density 
1.723
storage temp. 
2-8°C(protect from light)
pka
3.82±0.10(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A594545
Product name
2-Amino-5-bromo-4-methoxypyrimidine
Packaging
500mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139414
Product name
5-Bromo-4-methoxypyrimidin-2-amine
Packaging
2g
Price
$85
Updated
2021/12/16
AK Scientific
Product number
W5757
Product name
2-Amino-5-bromo-4-methoxypyrimidine
Packaging
1g
Price
$122
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139414
Product name
5-Bromo-4-methoxypyrimidin-2-amine
Packaging
5G
Price
$170
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0001620
Product name
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
Purity
95.00%
Packaging
1G
Price
$199.5
Updated
2021/12/16
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2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

155-90-8

36082-45-8

General procedure for the synthesis of 2-amino-5-bromo-4-methoxypyrimidine from 2-amino-4-methoxypyrimidine: Method 14; Synthesis of 5-bromo-4-methoxypyrimidin-2-ylamine; To a solution of 4-methoxypyrimidin-2-ylamine (1.84 g, 14.7 mmol) in chloroform (600 mL) was added N-bromosuccinimide (2.62 g, 14.7 mmol). The reaction mixture was stirred under light-avoiding conditions for 5 h. The reaction solution was transferred to a mixture of dichloromethane (200 mL) and 1N sodium hydroxide solution (100 mL). After thorough mixing, the organic and aqueous phases were separated, and the organic phase was washed with saturated sodium chloride solution (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2.88 g (96% yield) of the target compound 5-bromo-4-methoxypyrimidin-2-ylamine.LCMS (m/z): 204/206 (MH+).1H NMR (CDCl3): δ 8.10 ( s, 1H), 4.93 (bs, 2H), 3.96 (s, 3H).

References

[1] Patent: WO2008/98058, 2008, A1. Location in patent: Page/Page column 66
[2] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 99-100
[3] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[4] Patent: WO2009/93981, 2009, A1. Location in patent: Page/Page column 104-105
[5] Journal of the American Chemical Society, 1946, vol. 68, p. 1039,1040, 1044

2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Insight Chemical Solutions Ltd.
Tel
--
Fax
--
Email
info@insightchemicalsolutions.co.uk
Country
United Kingdom
ProdList
35
Advantage
50
Fulcrum Scientific Ltd.
Tel
--
Fax
--
Country
United Kingdom
ProdList
6565
Advantage
38
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View Lastest Price from 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE manufacturers

Dideu Industries Group Limited
Product
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE 36082-45-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-01
Career Henan Chemical Co
Product
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE 36082-45-8
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 724
Release date
2019-09-01