(+/-)AMETHOPTERIN

Product Name: (+/-)AMETHOPTERIN
CAS No.: 60388-53-6
Chemical Name: (+/-)AMETHOPTERIN
Synonyms: dl-MTX;6-mtx(dl);AKOS 93273;NSC 117356;-)AMETHOPTERIN;dl-methotrexate;dl-amethopterin;(+/-)AMETHOPTERIN;dl-Methylaminopterin;Methotrexate Impurity 3
CBNumber: CB7749012
Molecular Formula: C20H22N8O5
Formula Weight: 454.44
MOL File: 60388-53-6.mol

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(+/-)AMETHOPTERIN Property

Melting point:: 195 °C (dec.)(lit.)
Density: 1.536±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C.
form: powder
pka: 3.47±0.10(Predicted)
color: yellow

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Safety

Hazard Codes: T
Risk Statements: 61-25-36/38-23/24/25
Safety Statements: 53-26-36/37-45-36/37/39
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3
RTECS: MA1224100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M260680
Product name: DL-MethotrexateDipotassiumSaltDihydrate
Packaging: 250mg
Price: $1190
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002442
Product name: DL-AMETHOPTERIN
Purity: 95.00%
Packaging: 100MG
Price: $636.16
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52125
Product name: DL-MethotrexateDipotassiumSaltDihydrate
Packaging: 25mg
Price: $650
Updated: 2021/12/16

AvaChem

Product number: 3936
Product name: Racemethotrexate
Packaging: 10mg
Price: $39
Updated: 2021/12/16

AvaChem

Product number: 3936
Product name: Racemethotrexate
Packaging: 25mg
Price: $59
Updated: 2021/12/16

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(+/-)AMETHOPTERIN Chemical Properties,Usage,Production

Chemical Properties

yellow to orange crystalline powder

Uses

Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

Uses

(+/-)Amethopterin is a folic acid antagonist and anticancer agent.

Uses

Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist

Definition

ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.

(+/-)AMETHOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)AMETHOPTERIN Suppliers

Belgium 1 Canada 1 China 55 France 1 Germany 3 India 3 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 15 Global 84

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Alfa Chemistry

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American Custom Chemicals Corporation

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Ryan Scientific, Inc.

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Reagent World

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Kingston Chemistry

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ARVI Fine Organic Chemicals Co., Ltd.

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Riedel-de Haen AG

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HONEST JOY HOLDINGS LIMITED

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Sciencelab.com, Inc.

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Fisher Scientific

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Promega Corporation

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Acros Organics USA

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CLONTECH Laboratories, Inc.

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60388-53-6, (+/-)AMETHOPTERINRelated Search:

(+/-)AMETHOPTERIN Methotrexate sodium Methotrexate L-AMETHOPTERIN HYDRATE,L-(+)-AMETHOPTERIN HYDRATE,(+)-AMETHOPTERIN HYDRATE DL-Glutamic acid Folic acid Dichloromethotrexate METHOTREXATE DIMETHYL ESTER 7-CYANOMETHOTREXATE DIMETHYL ESTER 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3 METHOTREXATE-D3 METHOTREXATE SODIUM SALT, [3',5',7'-3H] 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid D-AMETHOPTERIN HYDRATE, 95 (-) - AMETHOPTERIN - D - METHOTREXATE,D(-)-AMETHOPTERIN,D-(-)-AMETHOPTERIN HYDRATE D(-)-AMETHOPTERIN HYDRATE, 98 DL-AMETHOPTERIN HYDRATE Fluoromethotrexate

6-mtx(dl)

dl-amethopterin

dl-methotrexate

n-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-dl-glutamicacid

AKOS 93273

(+/-)AMETHOPTERIN

DL-4-Amino-N10-methylpteroylglutamic acid

(plus-minus)-amethopterin

N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-DL-glutamic acid

DL-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)

NSC 117356

dl-Methylaminopterin

dl-MTX

DL-Amethopterin hydrate,95%

(±)Amethopterin hydrate,4-Amino-10-methylfolic acid, DL-4-Amino-N10-methylpteroylglutamic acid, MTX, Methylaminopterin

(plus-Minus)-aMethopterin(-20`C)

DL-Methotrexate DipotassiuM Salt Dihydrate

Methotrexate Impurity 3

Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

-)AMETHOPTERIN

2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid

MethotrexateImpurity3-d3

Methotrexate Impurity F

60388-53-6

C20H22N8O5xxH2O

DNA Synthesis Inhibitors

DNA metabolism

Apoptosis and Cell Cycle

Cell Signaling and Neuroscience

Cell Biology

BioChemical

RHEUMATREX