2-Phenoxyethyl chloride
- Product Name
- 2-Phenoxyethyl chloride
- CAS No.
- 622-86-6
- Chemical Name
- 2-Phenoxyethyl chloride
- Synonyms
- NSC 1073;-Chlorophenetole;B-CHLOROPHENETOLE;á-chlorophenetole;β-chlorophenetole;?-chlorophenetole;PHENOXYETHYLCHLORIDE;OMEGA-CHLOROPHENETOL;BETA-CHLOROPHENETOLE;2-Phenoxyethyl chlor
- CBNumber
- CB7775967
- Molecular Formula
- C8H9ClO
- Formula Weight
- 156.61
- MOL File
- 622-86-6.mol
2-Phenoxyethyl chloride Property
- Melting point:
- 28°C
- Boiling point:
- 97-98 °C15 mm Hg(lit.)
- Density
- 1.129 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.534(lit.)
- Flash point:
- 213 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform, Ethyl Acetate
- form
- Solid
- color
- Pale Yellow Oil to Low Melting Colorless
- BRN
- 971048
- CAS DataBase Reference
- 622-86-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, (2-chloroethoxy)-(622-86-6)
- EPA Substance Registry System
- (2-Chloroethoxy)benzene (622-86-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 114278
- Product name
- (2-Chloroethoxy)benzene
- Purity
- 98%
- Packaging
- 10ml
- Price
- $69.8
- Updated
- 2025/07/31
- Product number
- C0240
- Product name
- beta-Chlorophenetole
- Purity
- >95.0%(GC)
- Packaging
- 25mL
- Price
- $83
- Updated
- 2025/07/31
- Product number
- C0240
- Product name
- beta-Chlorophenetole
- Purity
- >95.0%(GC)
- Packaging
- 500mL
- Price
- $817
- Updated
- 2025/07/31
- Product number
- P319625
- Product name
- Phenyl2-ChloroethylEther
- Packaging
- 100g
- Price
- $325
- Updated
- 2021/12/16
- Product number
- 286791
- Product name
- Phenyl 2-chloroethyl ether
- Packaging
- 250g
- Price
- $456
- Updated
- 2021/12/16
2-Phenoxyethyl chloride Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Oil
Uses
Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.
Uses
(2-Chloroethoxy)benzene is used in the coupling reaction of benzaldehyde, cinnamyltrimethylsilane and anisole in the synthesis of pseudo-symmetrical tamoxifen derivatives.
Synthesis
122-99-6
622-86-6
At room temperature, 2.5 mL of N-methylpyrrolidone (NMP), 1.38 g (10 mmol) of 2-phenoxyethanol and 1.5 mL (11 mmol) of benzenesulfonyl chloride were added to the reaction flask. The mixture was stirred well and then the reaction was continuously stirred at 100 °C for 30 min. Upon completion of the reaction, the reaction mixture was cooled to room temperature and subsequently extracted by adding 30 mL of dichloromethane and 30 mL of water. The organic layer was separated and washed with saturated brine and dried over anhydrous sodium sulfate. Dichloromethane was removed by evaporation under reduced pressure to give the crude product. The crude product was purified by column chromatography to give 1.52 g of 2-chlorophenetole in colorless liquid form in 96.8% yield.
References
[1] Patent: CN106187674, 2016, A. Location in patent: Paragraph 0017; 0018
[2] Patent: US2016/347717, 2016, A1. Location in patent: Paragraph 0232; 0233
[3] Patent: US5527816, 1996, A
[4] Chemical Research in Toxicology, 2000, vol. 13, # 1, p. 53 - 62
[5] Patent: CN106146450, 2016, A. Location in patent: Paragraph 0132; 0133; 0134
2-Phenoxyethyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Phenoxyethyl chloride Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 010-88425576
- Fax
- (+86)-10-88425546
- sales@dhltchem.com
- Country
- China
- ProdList
- 793
- Advantage
- 59
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9718
- Advantage
- 55
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 86-13605431940 13605431940
- Fax
- 0086-0543-2240079
- zpmxchemical@126.com
- Country
- China
- ProdList
- 1490
- Advantage
- 62
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 400-1166-196 13458535857
- Fax
- QQ:800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 010-57903446 15869909019
- Fax
- 010-57903446
- 168931144@qq.com
- Country
- China
- ProdList
- 2875
- Advantage
- 58
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 86-021-61559134 15921386130
- Fax
- 021-55068248
- 3423497944@qq.com
- Country
- China
- ProdList
- 8144
- Advantage
- 55
- Tel
- 025-66028182 18626450290
- yftan@aikonchem.com
- Country
- China
- ProdList
- 16679
- Advantage
- 50
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-50426030 13856289449
- Fax
- 021-50426030
- 2630597085@qq.com
- Country
- China
- ProdList
- 1889
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 4009903999 13395398332
- Fax
- 0539-6365991
- sales@xiyashiji.com
- Country
- China
- ProdList
- 20794
- Advantage
- 60
- Tel
- 13552605092
- Fax
- 010-60593781
- tianyukanghong@163.com
- Country
- China
- ProdList
- 342
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0751-2886750 13927877953
- Fax
- 0751-2886750
- 3005811397@qq.com
- Country
- China
- ProdList
- 13305
- Advantage
- 58
- Tel
- 18031147013 18031147013;
- Fax
- 0311-68030586
- yeshengchemical@163.com
- Country
- China
- ProdList
- 2607
- Advantage
- 58
- Tel
- 13062833949; 4006653949 4006653949
- Fax
- QQ: 2136646215
- fred.wen@crcorporation.cn
- Country
- China
- ProdList
- 9755
- Advantage
- 58
- Tel
- 0411-0411-00000000 13644282108
- Fax
- -
- 3500508746@qq.com
- Country
- China
- ProdList
- 2896
- Advantage
- 55
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 0756-8828-007
- Fax
- 0756-8828 309
- Country
- China
- ProdList
- 38
- Advantage
- 58
- Tel
- 021-16621358918; 18516310516
- Fax
- 13045646768
- zhenlipharma888@163.com
- Country
- China
- ProdList
- 19035
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17987
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 400-6387771-6039 18920764717
- sales@heowns.com
- Country
- China
- ProdList
- 23771
- Advantage
- 60
- Tel
- 021-20921617 18957373295
- Fax
- 021-20921617
- 2240425080@qq.com
- Country
- China
- ProdList
- 891
- Advantage
- 58
- Tel
- 400-668-9898
- Fax
- 010-51582189
- service@3achem.com
- Country
- China
- ProdList
- 20557
- Advantage
- 58
- Tel
- 021-000000
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9853
- Advantage
- 58
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 9972
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 021-58581007 18019463053
- Fax
- 021-50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12878
- Advantage
- 58
- Tel
- 0751-2815688 13927872512
- Fax
- 0751-8963795
- 3007421951@qq.com
- Country
- China
- ProdList
- 9939
- Advantage
- 58
- Tel
- 13757609826
- sales@tzchemical.com
- Country
- China
- ProdList
- 216
- Advantage
- 58
- Tel
- +8615255079626
- eric@witopchemical.com
- Country
- China
- ProdList
- 23541
- Advantage
- 58
View Lastest Price from 2-Phenoxyethyl chloride manufacturers
- Product
- 2-Phenoxyethyl chloride 622-86-6
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 10 tons
- Release date
- 2021-07-20
- Product
- 2-Phenoxyethyl chloride 622-86-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25