ChemicalBook > CAS DataBase List > Oleclumab
Oleclumab
- Product Name
- Oleclumab
- CAS No.
- 1803176-05-7
- Chemical Name
- Oleclumab
- Synonyms
- Oleclumab;Oleclumab (anti-CD73);Research Grade Oleclumab;Research Grade Oleclumab(DHD46601)
- CBNumber
- CB78081035
- Formula Weight
- 0
- MOL File
- Mol file
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Oleclumab Property
- storage temp.
- Store at -20°C
- form
- Liquid
- color
- Colorless to light yellow
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Oleclumab Chemical Properties,Usage,Production
Uses
The CD73-antagonist antibody oleclumab inhibits cell surface-exposed CD73 and is currently undergoing clinical testing for cancer immunotherapy.
in vivo
Oleclumab (10 mg/kg; ip; every 3 days for 4 doses) increases the proportion of activated CD8+ lymphocyte populations in the mouse Balb/c syngeneic CT26 colon cancer tumor model. And Oleclumab significantly inhibits tumor growth[2].
| Animal Model: | Murine, Balb/c, syngeneic CT26 colon carcinoma tumor model[2] |
| Dosage: | 10 mg/kg |
| Administration: | ip; 2 time per week, for 2 weeks |
| Result: | Inhibited tumor growth by 50% or greater from study day 7 to study day 16 when compared with isotype control antibody-treated groups. |
Oleclumab Preparation Products And Raw materials
Raw materials
Preparation Products
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Oleclumab Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
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