ChemicalBook > CAS DataBase List > (R)-4-Benzyl-2-oxazolidinone

(R)-4-Benzyl-2-oxazolidinone

Product Name
(R)-4-Benzyl-2-oxazolidinone
CAS No.
102029-44-7
Chemical Name
(R)-4-Benzyl-2-oxazolidinone
Synonyms
(R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
CBNumber
CB7852611
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
102029-44-7.mol
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(R)-4-Benzyl-2-oxazolidinone Property

Melting point:
88-90 °C
alpha 
62 º (C=1, CHCl3)
Boiling point:
309.12°C (rough estimate)
Density 
1.1607 (rough estimate)
refractive index 
14.5 ° (C=5, MeOH)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly)
pka
12.78±0.40(Predicted)
form 
Crystalline Powder
color 
White to almost white
optical activity
[α]18/D +64°, c = 1 in chloroform
Water Solubility 
Insoluble in water. Soluble in Chloroform.
Sensitive 
Hygroscopic
BRN 
4782551
CAS DataBase Reference
102029-44-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
3-10
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
5g
Price
$24.68
Updated
2024/03/01
Sigma-Aldrich
Product number
300977
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
99%
Packaging
1G
Price
$35.8
Updated
2023/01/07
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
5g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
B1786
Product name
(R)-4-Benzyl-2-oxazolidinone
Purity
>98.0%(GC)
Packaging
25g
Price
$297
Updated
2024/03/01
Alfa Aesar
Product number
A16770
Product name
(R)-(+)-4-Benzyl-2-oxazolidinone, 99%
Packaging
1g
Price
$40.65
Updated
2024/03/01
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(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Usage,Production

Description

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

Chemical Properties

white to light yellow crystal powde

Uses

intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan

Uses

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

References

http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-4-Benzyl-2-oxazolidinone Suppliers

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View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers

Jinan Jianfeng Chemical Co., Ltd
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20ton
Release date
2024-08-14
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
99%min
Supply Ability
500kg
Release date
2021-09-22
hebei hongtan Biotechnology Co., Ltd
Product
(R)-4-Benzyl-2-oxazolidinone 102029-44-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-22

102029-44-7, (R)-4-Benzyl-2-oxazolidinoneRelated Search:


  • 4-benzyl-2-0xazolidinone
  • (R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+%
  • (R)-4-BENZYL-2-OXAZOLIDINONE 98.0%
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  • (R)-4-BenzyL
  • (R)-4-Benzyl-2-oxazolidinone &gt
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  • (R)-4-Benzyl-2-oxazolidinone USP/EP/BP
  • (R)-4-Benzyl-2-oxazolidinone CAS No. 102029-44-7
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