6-Bromonicotinic acid
- Product Name
- 6-Bromonicotinic acid
- CAS No.
- 6311-35-9
- Chemical Name
- 6-Bromonicotinic acid
- Synonyms
- 6-bromonicotine acid;6-BrNA;NSC 43545;AURORA 23320;AKOS BBS-00001340;6-BROMONICOTIC ACID;IFLAB-BB F1921-0015;IFLAB-BB F1926-0006;6-Bromonicotinicaci;6-BROMONICOTINC ACID
- CBNumber
- CB7854044
- Molecular Formula
- C6H4BrNO2
- Formula Weight
- 202.01
- MOL File
- 6311-35-9.mol
6-Bromonicotinic acid Property
- Melting point:
- 200-203 °C(lit.)
- Boiling point:
- 343.3±27.0 °C(Predicted)
- Density
- 1.813±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 3.24±0.10(Predicted)
- form
- Crystalline Powder
- color
- White
- InChI
- InChI=1S/C6H4BrNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)
- InChIKey
- JDJBRMNTXORYEN-UHFFFAOYSA-N
- SMILES
- C1=NC(Br)=CC=C1C(O)=O
- CAS DataBase Reference
- 6311-35-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 646989
- Product name
- 6-Bromopyridine-3-carboxylic acid
- Purity
- 96%
- Packaging
- 10g
- Price
- $107
- Updated
- 2025/07/31
- Product number
- 646989
- Product name
- 6-Bromopyridine-3-carboxylic acid
- Purity
- 96%
- Packaging
- 1g
- Price
- $25
- Updated
- 2023/06/20
- Product number
- B2961
- Product name
- 6-Bromonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $64
- Updated
- 2025/07/31
- Product number
- B2961
- Product name
- 6-Bromonicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $190
- Updated
- 2025/07/31
- Product number
- B686000
- Product name
- 6-Bromonicotinic Acid
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
6-Bromonicotinic acid Chemical Properties,Usage,Production
Chemical Properties
Off-white Plates
Uses
A potential hypolipidemic agent; a nicotinic acid analog
Synthesis
3510-66-5
6311-35-9
General procedure for the synthesis of 6-bromonicotinic acid from 2-bromo-5-methylpyridine: 2-bromo-5-methylpyridine (100 g, 0.291 mol) was dissolved in 1000 mL of water and Aliquat 336 (2 mL) was added as a phase transfer catalyst. Subsequently, potassium permanganate (251 g, 0.797 mol) was added slowly over 1 hr. The reaction mixture was stirred at 110 °C for 30 min and continued for 1 h to ensure complete reaction. Upon completion of the reaction, the mixture was filtered through diatomaceous earth while hot and the diatomaceous earth was washed with hot water. The filtrate was concentrated to half the original volume under reduced pressure. To the concentrate was added 48% hydrobromic acid (about 300 mL), and the precipitated 6-bromonicotinic acid crystals were filtered, washed with water and dried to give 52 g of white crystals in 44% yield. The product was characterized by 1H-NMR (CDCl3) with chemical shift δ (ppm) of 7.64 (1H, d, J = 8.0 Hz), 8.08 (1H, d, J = 8.0 Hz), 9.03 (1H, s).
References
[1] Synthesis, 1994, # 1, p. 87 - 92
[2] Journal of Materials Chemistry, 2005, vol. 15, # 48, p. 5164 - 5173
[3] Patent: EP1391451, 2004, A1. Location in patent: Page 143
[4] Journal of Organic Chemistry, 1949, vol. 14, p. 509,513
[5] Synthesis, 2003, # 4, p. 551 - 554
6-Bromonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Bromonicotinic acid manufacturers
- Product
- 6-Bromonicotinic acid 6311-35-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 6-Bromonicotinic acid 6311-35-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-30
- Product
- 6-Bromonicotinic acid 6311-35-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-26