2-Bromo-5-chloropyridine

Product Name: 2-Bromo-5-chloropyridine
CAS No.: 40473-01-6
Chemical Name: 2-Bromo-5-chloropyridine
Synonyms: IFLAB-BB F2124-0201;2-broMo-5-chloropyridin;2-Brome-5-chloropyridine;2-BROMO-5-CHLOROPYRIDINE;5-Chloro-2-bromopyridine;2-BroMoo-5-chloropyridine;2-Beromo-5-chloropyridine;Pyridine, 2-bromo-5-chloro-;2-broMo -5-chlorine pyridine;2-Bromo-5-chloropyridine,98%
CBNumber: CB9384264
Molecular Formula: C5H3BrClN
Formula Weight: 192.44
MOL File: 40473-01-6.mol

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2-Bromo-5-chloropyridine Property

Melting point:: 65-69 °C
Boiling point:: 128 °C / 16mmHg
Density: 1.736±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -1.49±0.10(Predicted)
form: Powder
color: Beige to yellow-brown
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C5H3BrClN/c6-5-2-1-4(7)3-8-5/h1-3H
InChIKey: BZUUVQCSPHPUQA-UHFFFAOYSA-N
SMILES: C1(Br)=NC=C(Cl)C=C1
CAS DataBase Reference: 40473-01-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-20/22-20/2236/37/38-20/21/22
Safety Statements: 36/37/39-26-22-22 26 36/37/39-36
RIDADR: Cool, dry,tightly closed
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T138401
Product name: 2-BROMO-5-CHLOROPYRIDINE
Purity: AldrichCPR
Packaging: 5MG
Price: $143
Updated: 2025/07/31

TCI Chemical

Product number: B2763
Product name: 2-Bromo-5-chloropyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: B2763
Product name: 2-Bromo-5-chloropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $37
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FB64674
Product name: 2-Bromo-5-chloropyridine
Packaging: 500g
Price: $195
Updated: 2021/12/16

Matrix Scientific

Product number: 011182
Product name: 2-Bromo-5-chloropyridine
Purity: 98%
Packaging: 500g
Price: $195
Updated: 2021/12/16

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2-Bromo-5-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields. It is also used in the synthesis of novel halopyridinylboronic acids and esters.

Synthesis

1072-98-6

40473-01-6

General procedure for the synthesis of 2-bromo-5-chloropyridine from 2-amino-5-chloropyridine: [Ref. Example 25] 5-(5-chloro-2-pyridinyl)-1-(3-pyridinyl)-1H-pyrazole-3-carboxylic acid; [show image] 1) Hydrogen bromide (12 ml, 47% aqueous solution) was slowly added to hydrogen bromide (12 ml, 47% aqueous solution) at 0 °C in a hydrobromic acid containing 2-amino-5-chloropyridine (5 g) ( 50 ml, 47%) solution. Subsequently, a solution of sodium nitrite (15 g) dissolved in water (20 ml) was added dropwise to the reaction mixture. The reaction solution was stirred at 0°C for 1 h. After that, a solution of sodium hydroxide (32 g) in water (80 ml) and ethyl acetate was added for extraction. The organic and aqueous phases were separated and the organic phase was dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give 2-bromo-5-chloropyridine (6.8 g, 91% yield) as a white solid. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 7.44 (1H, d, J = 8.42 Hz), 7.54 (1H, m), 8.36 (1H, s).

References

[1] Chemistry of Heterocyclic Compounds, 2017, vol. 53, # 2, p. 196 - 206
[2] Khim. Geterotsikl. Soedin., 2017, vol. 53, # 2, p. 196 - 206,11
[3] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 41
[4] Patent: EP1762568, 2007, A1. Location in patent: Page/Page column 24-25
[5] Patent: US5750545, 1998, A

2-Bromo-5-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Chloropyridine-2-boronic acid

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2-Bromo-5-chloropyridine Suppliers

Americas 1 Belgium 1 Canada 1 China 371 Europe 3 France 4 Germany 9 India 46 Japan 2 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 19 United States 55 Global 517

Beijing Sintong Pharma Technology Co., Ltd.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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View Lastest Price from 2-Bromo-5-chloropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Bromo-5-chloropyridine 40473-01-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-29

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Bromo-5-chloropyridine 40473-01-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Bromo-5-chloropyridine 40473-01-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

40473-01-6, 2-Bromo-5-chloropyridineRelated Search:

BCDMH Clopidol Chlorobromoisocyanurate 2-Chloro-3-cyanopyridine 1-Hexadecylpyridinium bromide 2-Bromopyridine Pentachloropyridine 2-Bromo-5-fluoropyridine 2-Chloro-5-chloromethylpyridine 2-BROMO-5-METHOXYPYRIDINE 2-Bromo-5-methylpyridine 2-Bromo-6-(trifluoromethyl)pyridine 2-Bromo-6-methylpyridine 2-BROMO-5-IODOBENZYL ALCOHOL 2-Bromo-5-nitropyridine 2-Bromo-5-(trifluoromethyl)pyridine 5-Amino-2-bromopyridine 6-Bromonicotinic acid

2-BROMO-5-CHLOROPYRIDINE

2-Brome-5-chloropyridine

IFLAB-BB F2124-0201

2-BROMO-5-CHLOROPYRIDINE, 98.5%

2-Bromo-5-chloropyridine,98%

5-Chloro-2-bromopyridine

2-BroMoo-5-chloropyridine

2-BroMo-5-chloropyridine, 98% 5GR

2-broMo-5-chloropyridin

2-broMo -5-chlorine pyridine

2-BroMo-5-chloropyridine, 97.0%(GC)

2 - broMine - 5 - chloro pyridine

2-Beromo-5-chloropyridine

Pyridine, 2-bromo-5-chloro-

2-Bromo-5-chloropyridine &gt

2-Bromo-5-chloropyridine ISO 9001：2015 REACH

40473-01-6

40473-01-06

C3H3BrClN

C5H3BrC1N

C4H2BrCIN

Chloropyridines

Bromopyridines

Halopyridines

Halides

Pyridines, Pyrimidines, Purines and Pteredines

Bromopyridines

Chloropyridines

Halopyridines

Boronic Acid

blocks

Bromides

Pyridines

Pyridine

Pyridine Series

bc0001