Aclatonium napadisilate

Product Name: Aclatonium napadisilate
CAS No.: 55077-30-0
Chemical Name: Aclatonium napadisilate
Synonyms: TM 723;Abovis;Aclatonium;aclatonium napadisilate;aclatonium napadisylate;(2-Acetoxypropionyl)choline;Napadisilic acid aclatonium;Aclatonium napadisilate USP/EP/BP;2-(2-acetyloxy-1-oxopropoxy)ethyl-trimethylammonium;2-[2-(Acetyloxy)-1-oxopropyloxy]-N,N,N-trimethylethanaminium
CBNumber: CB7855263
Molecular Formula: C30H44N2O14S2
Formula Weight: 720.80536
MOL File: 55077-30-0.mol

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Aclatonium napadisilate Property

Melting point:: 189-191°
solubility: DMSO (Slightly), Water (Slightly)
form: Solid
color: Crystals
Stability:: Hygroscopic

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Safety

Toxicity: LD50 in mice: 15 g/kg orally, 826 mg/kg s.c. (Miura); in dogs: >10 g/kg orally (Takai)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0079045
Product name: 2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-(2-(2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-DIMETHYL-AMMONIO)ETHYL)-DIMETHYL-AZANIUM NAPHTHALENE-1,5-DISULFONATE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0079045
Product name: 2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-(2-(2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-DIMETHYL-AMMONIO)ETHYL)-DIMETHYL-AZANIUM NAPHTHALENE-1,5-DISULFONATE
Purity: 95.00%
Packaging: 10G
Price: $1334.03
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18446
Product name: AclatoniumNapadisilate
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

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Aclatonium napadisilate Chemical Properties,Usage,Production

Originator

Abovis ,Toyama ,Japan ,1981

Uses

Aclatonium Napadisilate is a useful bioactive therapeutic agent for autoimmune diseases. A cholinergic agonist.

Manufacturing Process

5.2 g of bis(choline)-naphthalene-1,5-disulfonate was suspended in 30 ml of acetonitrile, and 10 g of lactic acid anhydride diacetate was added thereto. This mixture was refluxed for 3 hours. The resulting reaction mixture was allowed to stand at room temperature while cooling to precipitate the desired product crystals, which were collected by filtration. 5.5 g (76% yield) of the desired product having a melting point of 189°C to 191°C were obtained.

Therapeutic Function

Cholinergic

Safety Profile

Poison by intravenous route.Moderately toxic by subcutaneous route. An experimentalteratogen. Other experimental reproductive effects. Whenheated to decomposition it emits toxic fumes of NOx andSOx. A cholinergic agent.

Aclatonium napadisilate Preparation Products And Raw materials

Raw materials

Choline hydroxide Isopropyl acetate

Preparation Products

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Aclatonium napadisilate Suppliers

China 28 Germany 1 India 1 United States 2 Global 32

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10011
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

55077-30-0, Aclatonium napadisilateRelated Search:

Ammonium sulfamate Ethyl 2,4-dioxovalerate Cisatracurium besylate ISOXADIFEN-ETHYL Naphthalene-2-sulfonic acid Ethyl acrylate Sodium triacetoxyborohydride SILICON TETRAACETATE Ethylparaben acetic acid, triethoxy-, ethyl ester Diacerein Ethyl propiolate Ethyl acetate Ethyl cyanoacetate Ethanol Trimethylamine Acetoxyacetic acid Trinexapac-ethyl

2-(2-acetyloxypropanoyloxy)ethyl-[2-[2-(2-acetyloxypropanoyloxy)ethyl-dimethyl-ammonio]ethyl]-dimethyl-azanium naphthalene-1,5-disulfonate

aclatonium napadisilate

Aclatonium

1,5-Naphthalenedisulfonic acid, ion(2-), bis[2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium] (9CI)

Abovis

aclatonium napadisylate

2-(2-acetyloxy-1-oxopropoxy)ethyl-trimethylammonium

Ethanaminium, 2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethyl-, 1,5-naphthalenedisulfonate (2:1)

TM 723

(2-acetyllactoyloxyethyl)trimethylammonium 1,5-naphthalenedisulfonate

(2-acetyllactoyloxyethyl)trimethylammonium hemi-1,5-naphthalenedisulfonate

(2-Acetoxypropionyl)choline

2-[2-(Acetyloxy)-1-oxopropyloxy]-N,N,N-trimethylethanaminium

Napadisilic acid aclatonium

2-(2-acetyloxypropanoyloxy)ethyl-trimethylazanium,naphthalene-1,5-disulfonate

Aclatonium napadisilate USP/EP/BP

2-[2-(Acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium-1,5-naphthalenedisulfonate

55077-30-0

C30H46N2O14S2

C30H44N2O14S2