ChemicalBook > CAS DataBase List > Tiotropium bromide hydrate

Tiotropium bromide hydrate

Product Name
Tiotropium bromide hydrate
CAS No.
139404-48-1
Chemical Name
Tiotropium bromide hydrate
Synonyms
Tiotropium;BA-679 BR hydrate;TIOTROPIUM BROMDIE;tiotropium bromide hydrate;TiotropiuM broMide xhydrate;TIOTROPIUM BROMIDE MONOHYDRATE;Tiotropium bromide monohydrate CRS;Tiotropium Bromide hydrate (BA679BR);Tiotropium bromide hydrate USP/EP/BP;TiotropiuM BroMide MonohydrateTiotropiuM BroMide Monohydrate
CBNumber
CB7855399
Molecular Formula
C19H22BrNO4S2.H2O
Formula Weight
490.43
MOL File
139404-48-1.mol
More
Less

Tiotropium bromide hydrate Property

storage temp. 
Store at -20°C
solubility 
Sparingly soluble in water, soluble in methanol, practically insoluble in methylene chloride.
form 
Powder
InChIKey
MQLXPRBEAHBZTK-SEINRUQRSA-M
CAS DataBase Reference
139404-48-1(CAS DataBase Reference)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1890
Product name
Tiotropium Bromide Monohydrate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50mg
Price
$342
Updated
2024/03/01
ApexBio Technology
Product number
B1619
Product name
TiotropiumBromidehydrate
Packaging
5mg
Price
$133
Updated
2021/12/16
ApexBio Technology
Product number
B1619
Product name
TiotropiumBromidehydrate
Packaging
10mg
Price
$183
Updated
2021/12/16
Biorbyt Ltd
Product number
orb154653
Product name
Tiotropium Bromide hydrate (BA679BR)
Purity
>98%
Packaging
100mg
Price
$414.8
Updated
2021/12/16
Biorbyt Ltd
Product number
orb154653
Product name
Tiotropium Bromide hydrate (BA679BR)
Purity
>98%
Packaging
250mg
Price
$615.4
Updated
2021/12/16
More
Less

Tiotropium bromide hydrate Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white powder or crystals.

Uses

Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe

Definition

ChEBI: Tiotropium bromide hydrate is a hydrate that is the monohydrate form of tiotropium bromide. Used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist and a bronchodilator agent.

Clinical Use

Maintenance treatment of chronic obstructive pulmonary disease

Drug interactions

Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic drugs.
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.

Metabolism

Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4.

Tiotropium bromide hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tiotropium bromide hydrate Suppliers

Hangzhou Minsuo Technology Co., Ltd.
Tel
0571-0571-88199336 13355710209
Fax
0571-88190523
Email
sales@luckysagechem.com
Country
China
ProdList
56
Advantage
64
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2963
Advantage
65
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
More
Less

View Lastest Price from Tiotropium bromide hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tiotropium bromide hydrate 139404-48-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99%,EP/BP
Supply Ability
100kg/month
Release date
2021-06-25
Hebei Weibang Biotechnology Co., Ltd
Product
Tiotropium bromide hydrate 139404-48-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Yanxi Chemical Co., Ltd.
Product
Tiotropium Bromide monohydrate 139404-48-1
Price
US $100.00/kg
Min. Order
1kg
Purity
99% HPLC
Supply Ability
500KG/WEEK
Release date
2023-09-15

139404-48-1, Tiotropium bromide hydrateRelated Search:


  • (1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE
  • tiotropium bromide hydrate
  • TIOTROPIUM BROMIDE MONOHYDRATE
  • TIOTROPIUM BROMDIE
  • Tiotropium
  • (1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate
  • (1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide
  • TiotropiuM BroMide MonohydrateTiotropiuM BroMide Monohydrate
  • Tiotropium Bromide hydrate (BA679BR)
  • (1α,2β,4β,5α,7β)-7-[(Hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate
  • TiotropiuM broMide xhydrate
  • TiotropiuM BroMide Monohydrate or tiotropiuM broMide hydrate
  • Tiotropium bromide monohydrate CRS
  • BA-679 BR hydrate
  • 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, hydrate, (1α,2β,4β,5α,7β)- (9CI)
  • (1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide hydrate
  • Tiotropium bromide hydrate USP/EP/BP
  • 139404-48-1
  • 39404-48-1
  • C19H22NO4S2BrxH2O
  • BrC19H22NO4S2
  • C19H22BrNO4S2xH2O
  • C19H22NO4S2BrH2O
  • C19H22BrNO4S2
  • API
  • Inhibitors
  • 139404-48-1