Tiotropium bromide hydrate

Product Name: Tiotropium bromide hydrate
CAS No.: 139404-48-1
Chemical Name: Tiotropium bromide hydrate
Synonyms: Tiotropium;BA-679 BR hydrate;TIOTROPIUM BROMDIE;tiotropium bromide hydrate;TiotropiuM broMide xhydrate;TIOTROPIUM BROMIDE MONOHYDRATE;Tiotropium bromide monohydrate CRS;Tiotropium Bromide hydrate (BA679BR);Tiotropium bromide hydrate USP/EP/BP;TiotropiuM BroMide MonohydrateTiotropiuM BroMide Monohydrate
CBNumber: CB7855399
Molecular Formula: C19H22BrNO4S2.H2O
Formula Weight: 490.43
MOL File: 139404-48-1.mol

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Tiotropium bromide hydrate Property

storage temp.: Store at -20°C
solubility: Sparingly soluble in water, soluble in methanol, practically insoluble in methylene chloride.
form: Powder
InChIKey: MQLXPRBEAHBZTK-SEINRUQRSA-M
CAS DataBase Reference: 139404-48-1(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1890
Product name: Tiotropium Bromide Monohydrate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50mg
Price: $342
Updated: 2024/03/01

ApexBio Technology

Product number: B1619
Product name: TiotropiumBromidehydrate
Packaging: 5mg
Price: $133
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb154653
Product name: Tiotropium Bromide hydrate (BA679BR)
Purity: >98%
Packaging: 250mg
Price: $615.4
Updated: 2021/12/16

ApexBio Technology

Product number: B1619
Product name: TiotropiumBromidehydrate
Packaging: 50mg
Price: $741
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0077725
Product name: (1A,2B,4B,5A,7B)-7-[(HYDROXYDI-2-THIENYLACETY L)OXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4]NONANE BROMIDE HYDRATE
Purity: 95.00%
Packaging: 10MG
Price: $782.23
Updated: 2021/12/16

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Tiotropium bromide hydrate Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white powder or crystals.

Uses

Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe

Definition

ChEBI: Tiotropium bromide hydrate is a hydrate that is the monohydrate form of tiotropium bromide. Used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist and a bronchodilator agent.

Clinical Use

Maintenance treatment of chronic obstructive pulmonary disease

Drug interactions

Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic drugs.
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.

Metabolism

Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4.

Tiotropium bromide hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tiotropium bromide hydrate Suppliers

Canada 1 China 214 Europe 2 Germany 7 India 27 Israel 2 Italy 2 Poland 1 Spain 2 Switzerland 2 The Netherlands 1 United Arab Emirates 1 United Kingdom 6 United States 32 Global 300

Hangzhou Minsuo Technology Co., Ltd.

Tel: 0571-0571-88199336 13355710209
Fax: 0571-88190523
Email: sales@luckysagechem.com
Country: China
ProdList: 56
Advantage: 64

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2963
Advantage: 65

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9413
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

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View Lastest Price from Tiotropium bromide hydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Tiotropium bromide hydrate 139404-48-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99%,EP/BP
Supply Ability: 100kg/month
Release date: 2021-06-25

Hebei Weibang Biotechnology Co., Ltd

Product: Tiotropium bromide hydrate 139404-48-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

Hebei Yanxi Chemical Co., Ltd.

Product: Tiotropium Bromide monohydrate 139404-48-1
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99% HPLC
Supply Ability: 500KG/WEEK
Release date: 2023-09-15

139404-48-1, Tiotropium bromide hydrateRelated Search:

Tiotropium bromide 2-Thiophenecarboxaldehyde Dimidium bromide Chloral hydrate ETHANE Dacthal Dimethyl sulfate Allyl bromide Rocuronium bromide OXITROPIUM BROMIDE N,N-Dimethylformamide Dimethyl phthalate Dimethyl ether Dimethyl fumarate LACTOSE, MONOHYDRATE Thifensulfuron methyl Tetrahydrothiophene Cephalothin sodium

(1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE

tiotropium bromide hydrate

TIOTROPIUM BROMIDE MONOHYDRATE

TIOTROPIUM BROMDIE

Tiotropium

(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate

(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide

TiotropiuM BroMide MonohydrateTiotropiuM BroMide Monohydrate

Tiotropium Bromide hydrate (BA679BR)

(1α,2β,4β,5α,7β)-7-[(Hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate

TiotropiuM broMide xhydrate

TiotropiuM BroMide Monohydrate or tiotropiuM broMide hydrate

Tiotropium bromide monohydrate CRS

BA-679 BR hydrate

3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, hydrate, (1α,2β,4β,5α,7β)- (9CI)

(1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide hydrate

Tiotropium bromide hydrate USP/EP/BP

139404-48-1

39404-48-1

C19H22NO4S2BrxH2O

BrC19H22NO4S2

C19H22BrNO4S2xH2O

C19H22NO4S2BrH2O

C19H22BrNO4S2

API

Inhibitors

139404-48-1