ChemicalBook > CAS DataBase List > Octenidine dihydrochloride

Octenidine dihydrochloride

Product Name
Octenidine dihydrochloride
CAS No.
70775-75-6
Chemical Name
Octenidine dihydrochloride
Synonyms
Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%
CBNumber
CB7879838
Molecular Formula
C36H64Cl2N4
Formula Weight
623.82616
MOL File
70775-75-6.mol
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Octenidine dihydrochloride Property

Melting point:
215-217℃
Density 
1.046[at 20℃]
vapor pressure 
0Pa at 25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in dimethyl sulfoxide and methanol.
form 
Solid
color 
White to Off-White
Water Solubility 
14.2g/L at 20℃
Merck 
14,6754
Stability:
Hygroscopic
InChI
InChI=1S/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H
InChIKey
SMGTYJPMKXNQFY-UHFFFAOYSA-N
SMILES
[N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
LogP
1.5 at 23℃
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0388
Product name
Octenidine Dihydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
O0388
Product name
Octenidine Dihydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$114
Updated
2024/03/01
Alfa Aesar
Product number
H62257
Product name
Octenidine dihydrochloride, 98%
Packaging
1g
Price
$34.9
Updated
2024/03/01
Alfa Aesar
Product number
H62257
Product name
Octenidine dihydrochloride, 98%
Packaging
5g
Price
$137
Updated
2024/03/01
TRC
Product number
O239150
Product name
Octenidine Dihydrochloride
Packaging
5g
Price
$120
Updated
2021/12/16
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Octenidine dihydrochloride Chemical Properties,Usage,Production

Description

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Uses

Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.

Uses

Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.

Application

Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.

Flammability and Explosibility

Not classified

References

[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.

Octenidine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Octenidine dihydrochloride Suppliers

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View Lastest Price from Octenidine dihydrochloride manufacturers

Jinan Million Pharmaceutical Co., Ltd
Product
Octenidine dihydrochloride 70775-75-6
Price
US $1.00/kg
Min. Order
0.10000000kg
Purity
99%
Supply Ability
200KG
Release date
2024-10-12
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Octenidine Dihydrochloride 70775-75-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-19
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Octenidine HCl 70775-75-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-26

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