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crotetamide

Product Name
crotetamide
CAS No.
6168-76-9
Chemical Name
crotetamide
Synonyms
crotetamide;Crotethamide;N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide;N-[1-[(Dimethylamino)carbonyl]propyl]-N-ethyl-2-butenamide;2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-ethyl-
CBNumber
CB7904200
Molecular Formula
C12H22N2O2
Formula Weight
226.32
MOL File
6168-76-9.mol
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crotetamide Property

Melting point:
<25 °C
Boiling point:
bp0.03 132-134°
Density 
0.986±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Oil
pka
-0.74±0.70(Predicted)
color 
Colourless to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C818500
Product name
Crotethamide
Packaging
250mg
Price
$215
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156959
Product name
N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
Packaging
250mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0017118
Product name
CROTETHAMIDE
Purity
95.00%
Packaging
500MG
Price
$367.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156959
Product name
N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
Packaging
500mg
Price
$600
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD156959
Product name
N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
Packaging
1g
Price
$1050
Updated
2021/12/16
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crotetamide Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Oil

Originator

Micorene,Geisy

Uses

Analgesic; combination as respiratory stimulant.

Definition

ChEBI: Crotetamide is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

2-Clorobutiric acid dimethyl amide is dissolved in absolute benzene and heated to 110°-120°C with ethylamine in the autoclave. After cooling the ethylamine hydrochloride is filtered off, then the benzene solution is treated with water and freed from any dissolved ethylamine hydrochloride by means of potassium lye. After distillation of the benzene the 2-ethylaminobutyric acid dimethyl amide is rectified in vacuum.
2-Ethylaminobutyric acid dimethyl amide is dissolved in absolute ether, then the mixture is well cooled and treated drowsy under stirring with crotonic acid chloride. After a stirring reaction mixture is filtered and residue obtained is dissolved in water and treated by potassium hydroxide. The remaining product is finally rectified in high vacuum to give 2-(N-ethyl-crotonylamido)butyric acid dimethyl amide.

Therapeutic Function

Respiratory stimulant

crotetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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crotetamide Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

6168-76-9, crotetamideRelated Search:


  • Crotethamide
  • N-[1-[(Dimethylamino)carbonyl]propyl]-N-ethyl-2-butenamide
  • crotetamide
  • 2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-ethyl-
  • N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
  • 6168-76-9
  • Aliphatics
  • Amines
  • Intermediates & Fine Chemicals
  • Pharmaceuticals