crotetamide
- Product Name
- crotetamide
- CAS No.
- 6168-76-9
- Chemical Name
- crotetamide
- Synonyms
- crotetamide;Crotethamide;N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide;N-[1-[(Dimethylamino)carbonyl]propyl]-N-ethyl-2-butenamide;2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-ethyl-
- CBNumber
- CB7904200
- Molecular Formula
- C12H22N2O2
- Formula Weight
- 226.32
- MOL File
- 6168-76-9.mol
crotetamide Property
- Melting point:
- <25 °C
- Boiling point:
- bp0.03 132-134°
- Density
- 0.986±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- -0.74±0.70(Predicted)
- color
- Colourless to Light Yellow
N-Bromosuccinimide Price
- Product number
- C818500
- Product name
- Crotethamide
- Packaging
- 250mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- FD156959
- Product name
- N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- API0017118
- Product name
- CROTETHAMIDE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $367.5
- Updated
- 2021/12/16
- Product number
- FD156959
- Product name
- N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
- Packaging
- 500mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- FD156959
- Product name
- N-[1-(Dimethylcarbamoyl)propyl]-N-ethyl-but-2-enamide
- Packaging
- 1g
- Price
- $1050
- Updated
- 2021/12/16
crotetamide Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Oil
Originator
Micorene,Geisy
Uses
Analgesic; combination as respiratory stimulant.
Definition
ChEBI: Crotetamide is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Manufacturing Process
2-Clorobutiric acid dimethyl amide is dissolved in absolute benzene and
heated to 110°-120°C with ethylamine in the autoclave. After cooling the
ethylamine hydrochloride is filtered off, then the benzene solution is treated
with water and freed from any dissolved ethylamine hydrochloride by means
of potassium lye. After distillation of the benzene the 2-ethylaminobutyric acid
dimethyl amide is rectified in vacuum.
2-Ethylaminobutyric acid dimethyl amide is dissolved in absolute ether, then
the mixture is well cooled and treated drowsy under stirring with crotonic acid
chloride. After a stirring reaction mixture is filtered and residue obtained is
dissolved in water and treated by potassium hydroxide. The remaining product
is finally rectified in high vacuum to give 2-(N-ethyl-crotonylamido)butyric
acid dimethyl amide.
Therapeutic Function
Respiratory stimulant
crotetamide Preparation Products And Raw materials
Raw materials
Preparation Products
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