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BENZAMIL HYDROCHLORIDE

Product Name
BENZAMIL HYDROCHLORIDE
CAS No.
161804-20-2
Chemical Name
BENZAMIL HYDROCHLORIDE
Synonyms
Benzamil hydrochloride hydrate;Benzamil hydrate hydrochloride;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride;5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrate hydrochloride;3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide,hydrochloride;3;5-DIAMINO-6-CHLORO-N-[IMINO[(PHENYLMETHYL)AMINO]METHYL]-2-PYRAZINECARBOXAMIDE; MONOHYDROCHLORIDE
CBNumber
CB7973022
Molecular Formula
C13H15Cl2N7O
Formula Weight
356.21
MOL File
161804-20-2.mol
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BENZAMIL HYDROCHLORIDE Property

storage temp. 
2-8°C
solubility 
methanol: soluble10mg/mL
form 
solid
color 
yellow
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or may be stored at -20°C for up to 3 months.
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B2417
Product name
Benzamil hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
10mg
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
B2417
Product name
Benzamil hydrochloride hydrate
Purity
≥98% (HPLC)
Packaging
50mg
Price
$372
Updated
2024/03/01
Cayman Chemical
Product number
14313
Product name
Benzamil (hydrochloride)
Packaging
5mg
Price
$43
Updated
2024/03/01
Cayman Chemical
Product number
14313
Product name
Benzamil (hydrochloride)
Packaging
10mg
Price
$85
Updated
2024/03/01
TRC
Product number
B183630
Product name
BenzamilHydrochloride
Packaging
10mg
Price
$85
Updated
2021/12/16
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BENZAMIL HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Benzamil (161804-21-2) is a more potent (Ki = 10 nM vs 182 nM1, IC50 = 9 μM2) version of the epithelial sodium channel blocker Amiloride. It is also an inhibitor of Na+/Ca2+ exchange transport (IC50 = 11 μM)2 and the Na+/H+ antiporter (IC50 = 80 nM)2.

Uses

Benzamil Hydrochloride is a specific blocker of sodium channels. It also inhibits epithelial sodium channel (ENaC). Benzamil Hydrochloride is an analog of Amiloride (A578700).

Biochem/physiol Actions

Selective and potent blocker of Na+/H+ and Na+/Ca2+ channels

storage

Store at +4°C

References

Cuthbert and Fanelli (1978), Effects of some pyrazinecarboxamides on sodium transport in frog skin; J. Pharmacol. 63 139 Kleyman and Cragoe (1988), Amiloride and Its Analogs as Tools in the Study of Ion Transport; Membrane Biol. 105 1

BENZAMIL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BENZAMIL HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
BENZAMIL HYDROCHLORIDE 161804-20-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%HPLC
Supply Ability
200KG
Release date
2020-02-01

161804-20-2, BENZAMIL HYDROCHLORIDERelated Search:

MITOQ Lovastatin Isradipine Nicardipine hydrochloride

  • Benzamil hydrate hydrochloride
  • N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrate hydrochloride
  • N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
  • Benzamil hydrochloride hydrate
  • 3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide,hydrochloride
  • 3;5-DIAMINO-6-CHLORO-N-[IMINO[(PHENYLMETHYL)AMINO]METHYL]-2-PYRAZINECARBOXAMIDE; MONOHYDROCHLORIDE
  • 5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide
  • N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride
  • 161804-20-2