BENZAMIL HYDROCHLORIDE
- Product Name
- BENZAMIL HYDROCHLORIDE
- CAS No.
- 161804-20-2
- Chemical Name
- BENZAMIL HYDROCHLORIDE
- Synonyms
- Benzamil hydrochloride hydrate;Benzamil hydrate hydrochloride;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride;5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate;N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrate hydrochloride;3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide,hydrochloride;3;5-DIAMINO-6-CHLORO-N-[IMINO[(PHENYLMETHYL)AMINO]METHYL]-2-PYRAZINECARBOXAMIDE; MONOHYDROCHLORIDE
- CBNumber
- CB7973022
- Molecular Formula
- C13H15Cl2N7O
- Formula Weight
- 356.21
- MOL File
- 161804-20-2.mol
BENZAMIL HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- methanol: soluble10mg/mL
- form
- solid
- color
- yellow
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or may be stored at -20°C for up to 3 months.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B2417
- Product name
- Benzamil hydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $104
- Updated
- 2024/03/01
- Product number
- B2417
- Product name
- Benzamil hydrochloride hydrate
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $372
- Updated
- 2024/03/01
- Product number
- 14313
- Product name
- Benzamil (hydrochloride)
- Packaging
- 5mg
- Price
- $43
- Updated
- 2024/03/01
- Product number
- 14313
- Product name
- Benzamil (hydrochloride)
- Packaging
- 10mg
- Price
- $85
- Updated
- 2024/03/01
- Product number
- B183630
- Product name
- BenzamilHydrochloride
- Packaging
- 10mg
- Price
- $85
- Updated
- 2021/12/16
BENZAMIL HYDROCHLORIDE Chemical Properties,Usage,Production
Description
Benzamil (161804-21-2) is a more potent (Ki = 10 nM vs 182 nM1, IC50 = 9 μM2) version of the epithelial sodium channel blocker Amiloride. It is also an inhibitor of Na+/Ca2+ exchange transport (IC50 = 11 μM)2 and the Na+/H+ antiporter (IC50 = 80 nM)2.
Uses
Benzamil Hydrochloride is a specific blocker of sodium channels. It also inhibits epithelial sodium channel (ENaC). Benzamil Hydrochloride is an analog of Amiloride (A578700).
Biochem/physiol Actions
Selective and potent blocker of Na+/H+ and Na+/Ca2+ channels
storage
Store at +4°C
References
Cuthbert and Fanelli (1978), Effects of some pyrazinecarboxamides on sodium transport in frog skin; J. Pharmacol. 63 139 Kleyman and Cragoe (1988), Amiloride and Its Analogs as Tools in the Study of Ion Transport; Membrane Biol. 105 1
BENZAMIL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
BENZAMIL HYDROCHLORIDE Suppliers
View Lastest Price from BENZAMIL HYDROCHLORIDE manufacturers
- Product
- BENZAMIL HYDROCHLORIDE 161804-20-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%HPLC
- Supply Ability
- 200KG
- Release date
- 2020-02-01