ChemicalBook > CAS DataBase List > Quinapril hydrochloride

Quinapril hydrochloride

Product Name
Quinapril hydrochloride
CAS No.
82586-55-8
Chemical Name
Quinapril hydrochloride
Synonyms
ACCUPRIL;QUINAPRIL HCL;Korec;Conan;CI-906;Acupril;ccupril;ACCUPRO;Acequin;Acuitel
CBNumber
CB8100984
Molecular Formula
C25H31ClN2O5
Formula Weight
474.98
MOL File
82586-55-8.mol
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Quinapril hydrochloride Property

Melting point:
120-130°C
alpha 
D23 +14.5° (c = 1.2 in ethanol) (Klutchko); D25 +15.4° (c = 2 in methanol) (Goel, Krolls)
storage temp. 
2-8°C
solubility 
H2O: >10mg/mL
form 
solid
color 
white
CAS DataBase Reference
82586-55-8(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
NW7176000
HS Code 
2933492250
Hazardous Substances Data
82586-55-8(Hazardous Substances Data)
Toxicity
Freely sol in aq solvents. LD50 in male, female mice, rats (mg/kg): 1739, 1840, 4280, 3541 orally; 504, 523, 158, 107 i.v. (Kaplan, 1989)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Q0632
Product name
Quinapril hydrochloride
Purity
≥98% (HPLC), solid
Packaging
250mg
Price
$654
Updated
2024/03/01
Sigma-Aldrich
Product number
BP1193
Product name
Quinapril hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$229
Updated
2024/03/01
Sigma-Aldrich
Product number
1593401
Product name
Quinapril hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$364.4
Updated
2024/03/01
Alfa Aesar
Product number
J61913
Product name
Quinapril hydrochloride, 98%
Packaging
1g
Price
$255.65
Updated
2024/03/01
Alfa Aesar
Product number
J61913
Product name
Quinapril hydrochloride, 98%
Packaging
5g
Price
$650.65
Updated
2024/03/01
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Quinapril hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Antihypertensive;Dopamine receptor agonist

Uses

Quinapril is an angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.

Uses

Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.

Definition

ChEBI: Quinapril hydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. It has a role as an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a quinapril(1+).

brand name

Accupril (Pfizer); Quinapril (Lupin); Quinapril (Ranbaxy) .

General Description

Quinapril hydrochloride,(S)-[(S)-N-[(S)21-carboxy3-phenylpropyl]alanyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 1-ethyl ester hydrochloride(Acuretic), forms the diacid quinaprilate in thebody. It is more potent than captopril and equipotent to theactive form of enalapril.

Biochem/physiol Actions

Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.

Quinapril hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Quinapril
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View Lastest Price from Quinapril hydrochloride manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $99.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2021-12-21
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $19.00/KG
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20tons
Release date
2021-12-31
Zhuozhou Wenxi import and Export Co., Ltd
Product
Quinapril hydrochloride 82586-55-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

82586-55-8, Quinapril hydrochloride Related Search:

Topotecan hydrochloride Quinapril benzyl ester maleate Benazepril hydrochloride Lithium diisopropylamide ALTRENOGEST Mefloquine hydrochloride Triprolidine hydrochloride Betaine 1,1'-Carbonyldiimidazole CARBONYL SULFIDE Glycine Quinapril Carbonyl iron powder NICKEL CARBONYL Moexipril Isoquinoline-1-carboxylic acid QUINAPRIL-D5, HYDROCHLORIDE MOEXIPRIL-D5

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  • (3S)-2-[(2S)-2-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID HYDROCHLORIDE
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  • QuinaprilHclC25H30N205.HC1
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  • Quinapril hydrochloride in methanol
  • Acrylamide Impurity 5
  • 82586-55-8
  • 2586-55-8
  • C25H30N2O5HClC25H31ClN2O5
  • C25H31ClN2O5