ChemicalBook > CAS DataBase List > Ethyl 3-(pyridin-2-ylamino)propanoate

Ethyl 3-(pyridin-2-ylamino)propanoate

Product Name
Ethyl 3-(pyridin-2-ylamino)propanoate
CAS No.
103041-38-9
Chemical Name
Ethyl 3-(pyridin-2-ylamino)propanoate
Synonyms
Dabigatran Impurity 83;3-(Pyridin-2-ylamino)propanoate;Dabigatran Etexilate Impurity 90;N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER;Ethyl 3-(pyridin-2-ylamino)propan;N-2-pyridin-B-alanine ethyl ester;Ethyl 3-(2-PyridylaMino)propanoate;N-2-pyridinyl-β-Alanine,ethylester;Dabigatran Etexilate Intermdiate 4;Ethyl 3-(2-Pyridylamino)propionate
CBNumber
CB81011425
Molecular Formula
C10H14N2O2
Formula Weight
194.23
MOL File
103041-38-9.mol
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Ethyl 3-(pyridin-2-ylamino)propanoate Property

Melting point:
48-50°C
Boiling point:
125°C/0.2mmHg(lit.)
Density 
1.131±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO, Methanol
form 
Solid
pka
6.26±0.10(Predicted)
color 
White
InChI
InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12)
InChIKey
UITNIDFEANEWPC-UHFFFAOYSA-N
SMILES
C(OCC)(=O)CCNC1C=CC=CN=1
LogP
1.54 at 22℃ and pH6
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Safety

HS Code 
2933.39.9200
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1214
Product name
Ethyl 3-(2-Pyridylamino)propionate
Purity
>98.0%(T)
Packaging
5g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
E1214
Product name
Ethyl 3-(2-Pyridylamino)propionate
Purity
>98.0%(T)
Packaging
25g
Price
$79
Updated
2024/03/01
TRC
Product number
E925620
Product name
Ethyl3-(Pyridin-2-ylamino)propanoate
Packaging
10g
Price
$110
Updated
2021/12/16
TRC
Product number
E925620
Product name
Ethyl3-(Pyridin-2-ylamino)propanoate
Packaging
1g
Price
$45
Updated
2021/12/16
TRC
Product number
E925620
Product name
Ethyl3-(Pyridin-2-ylamino)propanoate
Packaging
5g
Price
$70
Updated
2021/12/16
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Ethyl 3-(pyridin-2-ylamino)propanoate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Dabigatran etexilate intermediate

Uses

Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.

Synthesis

A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.

Ethyl 3-(pyridin-2-ylamino)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 3-(pyridin-2-ylamino)propanoate Suppliers

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View Lastest Price from Ethyl 3-(pyridin-2-ylamino)propanoate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Ethyl 3- (pyridin-2-ylamino) Propanoate 103041-38-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Zibo Wei Bin Import & Export Trade Co. Ltd.
Product
N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER 103041-38-9
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T
Release date
2023-07-18
Henan Fengda Chemical Co., Ltd
Product
N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER 103041-38-9
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16

103041-38-9, Ethyl 3-(pyridin-2-ylamino)propanoateRelated Search:

Glycidyl methacrylate 4-Aminobenzamidine dihydrochloride N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate Dabigatran ethyl AcOH Salt 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE 3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER

  • N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER
  • N-2-pyridinyl-β-Alanine,ethylester
  • ethyl (2R)-2-[(pyridin-2-yl)amino]propanoate
  • Ethyl-3-(pyridin-2yl-Amino)propionate
  • Ethyl-3-(pyridine-2-ylamino)propanoate
  • N-2-Pyridyl-beta-alanin ethyl ester
  • ethyl 3-(pyridin-2-ylamino)propanoate
  • ethyl (2S)-2-[(pyridin-2-yl)aMino]propanoate
  • 3-(Pyridin-2-ylaMino)-propionic acid ethyl ester
  • Ethyl 3-(2-PyridylaMino)propanoate
  • N-Ethyl 3-(pyridin-2-ylaMino)propanoate
  • N-Pyridin-2-yl-beta-alanine ethyl ester
  • β-Alanine, N-2-pyridinyl-, ethyl ester
  • N-2-pyridinyl-, ethyl ester Alanine
  • Dabigatran Etexilate Intermdiate 4
  • Ethyl 3-(2-Pyridylamino)propionate
  • N-2-Pyridinyl-b-alanine ethyl ester
  • N-2-Pyridinyl-beta-alanine ethyl ester
  • 3-(Pyridin-2-ylamino)propanoate
  • 3-(2-Pyridylamino)propionic Acid Ethyl Ester
  • N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER USP/EP/BP
  • Ethyl 3-(pyridin-2-ylamino)propan
  • Dabigatran Etexilate Impurity 90
  • N-2 pyridine -B- alanine ethyl ester
  • Ethyl 3-(pyridin-2-Ethyl 3-(pyridin-2-ylamino)propanoateylamino)propanoate
  • N-2-Pyridinyl-β-Alanine,ethylester
  • N-2-Pyridinyl-?-Alanineethylester (DBI1)
  • Ethyl 3-(Pyridin-2-ylamino)-propionoate
  • Ethyl N-(2-pyridyl)-3-aminopropionate
  • Ethyl-3-(pyridine-2yl amino)propane
  • N-2-pyridin-B-alanine ethyl ester
  • Dabigatran Impurity 83
  • 103041-38-9
  • 103041-39-9
  • Intermediate of Dabigatran
  • For API's Production
  • Aromatics
  • Heterocycles
  • john's