Pamidronic acid
- Product Name
- Pamidronic acid
- CAS No.
- 40391-99-9
- Chemical Name
- Pamidronic acid
- Synonyms
- DLV;AHPrBP;Panolin;amidronate;Rescriptor;Pamidronicaci;PAMIDRONIC ACID;Iflab-bb F1977-0047;Delavirdine mesylate;Ibandronate Impurity 23
- CBNumber
- CB8107554
- Molecular Formula
- C3H11NO7P2
- Formula Weight
- 235.07
- MOL File
- 40391-99-9.mol
Pamidronic acid Property
- Melting point:
- 226-228°C
- Boiling point:
- 658.7±65.0 °C(Predicted)
- Density
- 1.998±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Methanol (Very Slightly, Heated, Sonicated), Water (Slightly, Heated, Sonicated)
- pka
- 1.44±0.10(Predicted)
- form
- Solid
- color
- Light Brown to Beige
- Stability:
- Hygroscopic
Safety
- HS Code
- 9999999999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 4149
- Product name
- Delavirdine mesylate
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $634
- Updated
- 2021/12/16
- Product number
- P172490
- Product name
- PamidronicAcid
- Packaging
- 50mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 462007
- Product name
- Pamidronic Acid
- Packaging
- 50mg
- Price
- $368
- Updated
- 2021/12/16
- Product number
- 2631AH
- Product name
- Pamidronicacid
- Packaging
- 1g
- Price
- $158
- Updated
- 2021/12/16
- Product number
- orb134480
- Product name
- Pamidronic acid
- Purity
- >99%
- Packaging
- 100mg
- Price
- $510
- Updated
- 2021/12/16
Pamidronic acid Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Aredia,Novartis,India
Uses
A biphosphonate bone resorption inhibitor.
Uses
anticancer
Definition
ChEBI: Pamidronate is a phosphonoacetic acid.
Manufacturing Process
For a batch size of 5 L, 587.5 g (3.2 moles) of mannitol is dissolved in 3.5 L of water. Pamidronic acid (31.6 g, 0.133 moles) is mixed with a 1.0 L aliquot of the mannitol solution to form a slurry. The slurry is then transferred into the remainder of the mannitol solution, and stirred for at least 15 min. Aqueous 1 N sodium hydroxide (270 ml) is then added and the mixture is stirred until a clear, colorless solution results. The pH is then adjusted to 6.50.1 using either 1 M aqueous phosphoric acid or 1 N aqueous sodium hydroxide, as needed. The solution is then filtered through a 0.22 micron filter, and filled at 20°C into vials at 4.0 ml (4.172 g)/vial, under sterile conditions. The aqueous solution is frozen at -37°C and lyophilized (20 mbar, 20°-40°C) to yield 1,250 vials, each containing 30 mg of amorphous disodium pamidronate. The vials are sealed under positive nitrogen pressure. The disodium pamidronate is amorphous (noncrystalline) by X-ray diffraction and contains 0.7 wt-% water.
brand name
Rescriptor (Agouron).
Therapeutic Function
Bone resorption suppressant
Pamidronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pamidronic acid manufacturers
- Product
- Pamidronic acid 40391-99-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10kg/month
- Release date
- 2021-06-21
- Product
- Pamidronic acid 40391-99-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-28