ChemicalBook > CAS DataBase List > Vildagliptin Chloroacetyl Nitrile (R)-Isomer

Vildagliptin Chloroacetyl Nitrile (R)-Isomer

Product Name
Vildagliptin Chloroacetyl Nitrile (R)-Isomer
CAS No.
565452-98-4
Chemical Name
Vildagliptin Chloroacetyl Nitrile (R)-Isomer
Synonyms
Vildagliptin?Chloroacetyl Nitrile (R)-Isomer;(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;Vildagliptin Impurity 7;Vildagliptin impurities14;(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile;(2R)-1-(chloroacetyl) pyrroIidine-2-carbonitriIe;(2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile;2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-;2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)
CBNumber
CB81085136
Molecular Formula
C7H9ClN2O
Formula Weight
172.61
MOL File
565452-98-4.mol
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Property

Melting point:
64-67°C
Boiling point:
363.1±37.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
-4.65±0.40(Predicted)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C363785
Product name
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Packaging
250mg
Price
$150
Updated
2021/12/16
TRC
Product number
C363785
Product name
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Packaging
2.5g
Price
$1190
Updated
2021/12/16
Activate Scientific
Product number
AS100986
Product name
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Purity
95% ee
Packaging
1g
Price
$380
Updated
2021/12/16
Activate Scientific
Product number
AS100986
Product name
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Purity
95% ee
Packaging
5G
Price
$1115
Updated
2021/12/16
ACHEMBLOCK
Product number
P37376
Product name
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Purity
95%
Packaging
250MG
Price
$155
Updated
2021/12/16
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Chemical Properties,Usage,Production

Uses

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.

Vildagliptin Chloroacetyl Nitrile (R)-Isomer Preparation Products And Raw materials

Raw materials

Preparation Products

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565452-98-4, Vildagliptin Chloroacetyl Nitrile (R)-IsomerRelated Search:


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