ChemicalBook > CAS DataBase List > Vildagliptin Chloroacetyl Nitrile (R)-Isomer
Vildagliptin Chloroacetyl Nitrile (R)-Isomer
- Product Name
- Vildagliptin Chloroacetyl Nitrile (R)-Isomer
- CAS No.
- 565452-98-4
- Chemical Name
- Vildagliptin Chloroacetyl Nitrile (R)-Isomer
- Synonyms
- Vildagliptin?Chloroacetyl Nitrile (R)-Isomer;(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;Vildagliptin Impurity 7;Vildagliptin impurities14;(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile;(2R)-1-(chloroacetyl) pyrroIidine-2-carbonitriIe;(2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile;(2R)-1-(CHLOROACETYL) PYRROLIDINE-2- CARBONITRILE;2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-
- CBNumber
- CB81085136
- Molecular Formula
- C7H9ClN2O
- Formula Weight
- 172.61
- MOL File
- 565452-98-4.mol
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Property
- Melting point:
- 64-67°C
- Boiling point:
- 363.1±37.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- -4.65±0.40(Predicted)
- form
- Solid
- color
- White to Pale Yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- C363785
- Product name
- (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
TRC
- Product number
- C363785
- Product name
- (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
- Packaging
- 2.5g
- Price
- $1190
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS100986
- Product name
- (R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
- Purity
- 95% ee
- Packaging
- 5G
- Price
- $1115
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS100986
- Product name
- (R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
- Purity
- 95% ee
- Packaging
- 1g
- Price
- $380
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11103431
- Product name
- (R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
- Purity
- 95+%
- Packaging
- 1g
- Price
- $381
- Updated
- 2021/12/16
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Chemical Properties,Usage,Production
Uses
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
Vildagliptin Chloroacetyl Nitrile (R)-Isomer Preparation Products And Raw materials
Raw materials
Preparation Products
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565452-98-4, Vildagliptin Chloroacetyl Nitrile (R)-IsomerRelated Search:
Cyanuric acid
3-Amino-1-hydroxyadamantane
Vildagliptin Carboxylic Acid
2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)
L-Proline, 4-chloro-, trans-
1,3,5,7-tetrahydroxyadamantane
Amantadine
N-acetic acid-1-aMino-3-adaMantanol
Vildagliptin IMpurity 2 (Mixture of DiastereoMers)
1-Adamantanol
Vildagliptin Impurity 25
Dichloroacetyl chloride
2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI)
Vildagliptin iMpurity A-F
pyrrolidine-2-carbonitrile 2,2,2-trifluoroacetate
methyl L-prolinate
Vildagliptin Impurity 6
Vildagliptin Impurity 19