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Vildagliptin Chloroacetyl Nitrile (R)-Isomer

Product Name
Vildagliptin Chloroacetyl Nitrile (R)-Isomer
CAS No.
565452-98-4
Chemical Name
Vildagliptin Chloroacetyl Nitrile (R)-Isomer
Synonyms
Vildagliptin?Chloroacetyl Nitrile (R)-Isomer;(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;Vildagliptin Impurity 7;Vildagliptin impurities14;(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile;(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile;(2R)-1-(chloroacetyl) pyrroIidine-2-carbonitriIe;(2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile;2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-;2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)
CBNumber
CB81085136
Molecular Formula
C7H9ClN2O
Formula Weight
172.61
MOL File
565452-98-4.mol
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Property

Melting point:
64-67°C
Boiling point:
363.1±37.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
-4.65±0.40(Predicted)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C363785
Product name
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Packaging
250mg
Price
$150
Updated
2021/12/16
TRC
Product number
C363785
Product name
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Packaging
2.5g
Price
$1190
Updated
2021/12/16
Activate Scientific
Product number
AS100986
Product name
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Purity
95% ee
Packaging
5G
Price
$1115
Updated
2021/12/16
Activate Scientific
Product number
AS100986
Product name
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Purity
95% ee
Packaging
1g
Price
$380
Updated
2021/12/16
Crysdot
Product number
CD11103431
Product name
(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
Purity
95+%
Packaging
1g
Price
$381
Updated
2021/12/16
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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Chemical Properties,Usage,Production

Uses

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.

Vildagliptin Chloroacetyl Nitrile (R)-Isomer Preparation Products And Raw materials

Raw materials

Preparation Products

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Vildagliptin Chloroacetyl Nitrile (R)-Isomer Suppliers

China 71 Europe 1 India 6 United Kingdom 1 United States 5 Global 84
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565452-98-4, Vildagliptin Chloroacetyl Nitrile (R)-IsomerRelated Search:

Cyanuric acid 3-Amino-1-hydroxyadamantane Vildagliptin Carboxylic Acid 2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI) L-Proline, 4-chloro-, trans- 1,3,5,7-tetrahydroxyadamantane Amantadine N-acetic acid-1-aMino-3-adaMantanol Vildagliptin IMpurity 2 (Mixture of DiastereoMers) 1-Adamantanol Vildagliptin Impurity 25 Dichloroacetyl chloride 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI) Vildagliptin iMpurity A-F pyrrolidine-2-carbonitrile 2,2,2-trifluoroacetate methyl L-prolinate Vildagliptin Impurity 6 Vildagliptin Impurity 19

  • 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)
  • (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
  • (R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
  • Vildagliptin Impurity 15/Vildagliptin Chloroacetyl Nitrile (R)-Isomer/(1S)-2-(2-chloroacetyl)cyclopentane-1-carbonitrile
  • Vildagliptin?Chloroacetyl Nitrile (R)-Isomer
  • (R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
  • Vildagliptin Impurity 7
  • 2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-
  • (2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
  • Vildagliptin impurities14
  • (R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile? (Vildagliptin Impurity）
  • (2R)-1-(chloroacetyl) pyrroIidine-2-carbonitriIe
  • Vildagliptin Chloroacetyl Nitrile (R)-Isomer Vildagliptin Chloroacetyl Nitrile (R)-Isomer
  • 2-(((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)amino)acetic acid
  • 565452-98-4
  • ACETYLHALIDE
  • Heterocycles, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals