ChemicalBook > CAS DataBase List > Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-1

Product Name: Palmitoyl Tripeptide-1
CAS No.: 147732-56-7
Chemical Name: Palmitoyl Tripeptide-1
Synonyms: Pal-AHK;L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-;Pal-GHK-OH;Collaxyl II;WrinFix-P3P1;Palmitoyl-GHK;Pal-GHK, >=95%;Pal-Tripeptide-1;Palm-Gly-His-Lys;Peptides PAL-Ghk
CBNumber: CB81214020
Molecular Formula: C30H54N6O5
Formula Weight: 578.79
MOL File: 147732-56-7.mol

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Palmitoyl Tripeptide-1 Property

Boiling point:: 913.0±65.0 °C(Predicted)
Density: 1.105
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml
form: A solid
pka: 3.16±0.10(Predicted)
color: White to off-white
Sequence: Pal-Gly-His-Lys
InChIKey: BYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILES: C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27059
Product name: Pal-GHK
Packaging: 100mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 27059
Product name: Pal-GHK
Packaging: 250mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 27059
Product name: Pal-GHK
Packaging: 500mg
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 27059
Product name: Pal-GHK
Packaging: 1g
Price: $384
Updated: 2024/03/01

TRC

Product number: P161025
Product name: PalmitoylTripeptide-1
Packaging: 250mg
Price: $100
Updated: 2021/12/16

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Palmitoyl Tripeptide-1 Chemical Properties,Usage,Production

Description

A peptide is two or more amino acids joined together and is the building block of protein. Peptides fall into three main categories: signal peptides, carrier peptides, and those that inhibit nerve signals. Signal peptides, like palmitoyl tripeptide-1, act as messengers to cells, which trigger collagen synthesis, which then increases skin firmness.Palmitoyl tripeptide-1 is a small three amino acid signal peptide with the amino sequence of glycine-histidine-lysine (GHK). GHK is attached to palmitic acid (a fatty acid) to increase its skin penetration and oil solubility.

Description

Pal-GHK is a form of the extracellular matrix-derived peptide GHK containing palmitic acid , which allows it to penetrate the stratum corneum to the epidermal and dermal skin layers. Pal-GHK (0.5 μM) increases collagen synthesis in human skin fibroblasts in vitro. It reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light when used at a concentration of 6 ppm. It has been used with the zwitterionic surfactant C₁₂ dodecyldimethylamine oxide (C₁₂DMAO) to study self-assembly of the mixture into aggregates, ribbons, and nanobelts. Pal-GHK has also been used as an internal standard for the quantification of pal-KTTKS in anti-wrinkle creams by LC-MS/MS.

Uses

Palmitoyl Tripeptide-1, has shown to have effects on on collagen, fibronectin, hyaluronic acid synthesis in human dermal fibroblasts, and thus can be used in preparation of antiaging cosmetic creams.

Application

Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed? PT1P) is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams. Acting as messengers of cutaneous restructuration and repair, this peptide works synergistically to restore and maintain the skin's youthful appearance.

Clinical Use

Applying palmitoyl tripeptide-1 directly to your skin tells the cells to make more collagen, stimulating new collagen production. It requires at least one month or more to begin to see visible changes from new collagen with maximum results visible after 3 to 4 months. Erin Gilbert, MD, FAAD, Ph.D., and board-certified dermatologist and neuroscientist, continues: "Peptides can be included in serums, moisturizers, and masks," Gilbert explains. "They are also included in some topical serums used after micro-needling or superficial laser procedures to increase the penetration of the peptide and help the skin recover from the procedure."

Safety

The CIR Expert Panel concluded that peptides, such as palmitoyl tripeptide-1, are safe in cosmetics and self-care products. Environmental Working Group (EWG) currently scores palmitoyl tripeptide-1 as “1” or “low hazard.”Overall, peptides, such as palmitoyl tripeptide-1, mimic what already exists in the human body and research on peptides’ impact on the skin shows limited to no skin irritation. In terms of toxicity caused by peptides, there is no published research to document any known toxicity.

References

[1] LINTNER P. Biologically active peptides: from a laboratory bench curiosity to a functional skin care product[J]. International Journal of Cosmetic Science, 2001, 22 3: 207-218. DOI: 10.1046/j.1467-2494.2000.00010.x
[2] HAN ZHANG . Modulating self-assembly behavior of a salt-free peptide amphiphile (PA) and zwitterionic surfactant mixed system[J]. Journal of Colloid and Interface Science, 2016, 467: Pages 43-50. DOI: 10.1016/j.jcis.2015.12.005
[3] VALERIA CASTELLETTO. Self-Assembly of Palmitoyl Lipopeptides Used in Skin Care Products[J]. Langmuir, 2013, 29 29: 9149-9155. DOI: 10.1021/la401771j
[4] RALUCA-IOANA CHIRITA . Development of a LC–MS/MS method to monitor palmitoyl peptides content in anti-wrinkle cosmetics[J]. Analytica Chimica Acta, 2009, 641 1: Pages 95-100. DOI: 10.1016/j.aca.2009.03.015

Palmitoyl Tripeptide-1 Preparation Products And Raw materials

Raw materials

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View Lastest Price from Palmitoyl Tripeptide-1 manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Palmitoyl Tripeptide-1 147732-56-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-11-13

Chengdu Shengnuo Biopharm Co.,Ltd

Product: Palmitoyl Tripeptide-1 147732-56-7
Price: US $500.00-500.00/kg
Min. Order: 1kg
Purity: ≥99.00%
Supply Ability: 1000000
Release date: 2025-10-10

Jinan Ruitong Biotech Co., Ltd.

Product: Palmitoyl Tripeptide-1 147732-56-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1
Release date: 2025-09-05

147732-56-7, Palmitoyl Tripeptide-1Related Search:

PALMITOYL TETRAPEPTIDE-3 Argireline Tripeptide-1 TYR-D-ALA-GLY-PHE-LEU (2S)-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-2,4-diaminobutanoic acid bis(trifluoroacetate) Acetyl Dipeptide-1 cetyl ester MET-GLU-HIS-PHE-ARG-TRP-GLY Rigin Biotinoyl tripeptide-1 Nonapeptide-1 Copper Peptide L-Carnosine Acetyl Octapeptide-3 Palmitoyl Pentapeptide Myristoyl Pentapeptide-17 Palmitoyl Tripeptide-5 Acetyl Tetrapeptide-5 Dipeptide-2

L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-

Palmitoyl Tripeptide-1Pal-AHK

N2-[(N-Palmitoylglycyl)-L-histidyl]-L-lysine

Pal-GHK(PalMitoyl Tripeptide-1)

N-(1-Oxohexadecyl)glycyl-L-histidyl-L-lysine

N2-[N-[N-(1-oxohexadecyl)glycyl]-L-histidyl]-L-lysine

PalMitoyl Tripeptide-1、3

Pal-GHK, >=95%

Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7

Pal-GHK | Pal-Gly-His-Lys

Palmiltoyl Tripeptide-1 (Pal-GHK)

Palmitoyl Tripeptide-1、Palmitoyl Oligopeptide

Matrixyl 3000 / Pal-GHK/ Palmitoyl Tripeptide-1

Pal-AHK

Palmitoyl Tripeptide-1, Bio-bustyl

PAL-GLY-HIS-LYS-OH

Palmitoyl Tripeptide-1/Pal-GHK

Collaxyl II / Palmitoyl tripeptide-1, Biopeptide CL

Collaxyl II

Palmiltoyl Tripepti

Matrixyl 3000 powder / Palmitoyl Tripeptide-1

Pal-Tripeptide-1

Cosmetic peptide powder/Pal-AHK

N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine

PAL-GHK (Palmitoyl-Oligopeptide)

Cosmetic Peptides Palmitoyl Tripeptide-1 Anti-Wrinkle

Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 USP/EP/BP

N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine USP/EP/BP

Peptide Palmitoyl Tripeptide-1 PAL-GHK

Peptide Palmitoyl Tripeptide-1 (PAL-GHK / palmitoyl-GHK)

PAL-GHK / palmitoyl-GHK

Material Pure Palmitoyl Tripeptide-1

Cosmetic Raw Material Pure Palmitoyl Tripeptide-1

superior quality N-1(1-oxohexadecyl-glycyl-L-histidyl-L-Lysine CAS 147732-56-7

Pal-GHK-OH

N-Palmitoylglycyl-L-histidyl-L-lysine

Palmitoyl-GHK

Palmitoyl Tripeptide-3 (Pal-AHK)Palmitoyl Tripeptide-3 (Pal-AHK)

Palm-Gly-His-Lys

Peptides PAL-Ghk

Palmitoyl Tetrapeptide-1

China biggest manufacturer, Palmitoyl Tripeptide,147732-56-7

Palmitoyl Tripeptide-1 / Pal-GHK/Matrixyl 3000

PALMITOYL TRIPEPTIDE-1

(S)-2-((S)-3-(1H-Imidazol-5-yl)-2-(2-palmitamidoacetamido)propanamido)-6-aminohexanoic acid

Palmitoyl Tripeptide-1 (PalGHK)Palmitoyl Tripeptide-1 (PalGHK)

Pal-GHK/Matrixyl 3000

WrinFix-P3P1

oil Palmitoyl Tripeptide-1

147732-56-7

C30H54N6O5

Cosmetics beauty peptide

147732-56-7