Polyhexamethyleneguanidine hydrochloride
Description Uses Toxicity- Product Name
- Polyhexamethyleneguanidine hydrochloride
- CAS No.
- 57028-96-3
- Chemical Name
- Polyhexamethyleneguanidine hydrochloride
- Synonyms
- PHMG;PHMG hydrochloride;PHMC;Polyhexamethylene guanide hydrochloride;Polyhexamethylene Guanidine Hydrchloride;PolyhexaMethylene guaidine hydrochloride and phosphate;PHMG99%;99% powder;PHMG powder;PHMG chloride
- CBNumber
- CB81230558
- Molecular Formula
- C7H22ClN5
- Formula Weight
- 211.74
- MOL File
- 57028-96-3.mol
Polyhexamethyleneguanidine hydrochloride Property
- Melting point:
- >222°C (sub.)
- storage temp.
- Refrigerator, Under inert atmosphere
- solubility
- DMSO (Soluble, Heated), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C6H16N2.CH5N3.ClH/c7-5-3-1-2-4-6-8;2-1(3)4;/h1-8H2;(H5,2,3,4);1H
- InChIKey
- REZCJHXVNVUWGF-UHFFFAOYSA-N
- SMILES
- C(N)(N)=N.C(CCN)CCCN.Cl
- CAS DataBase Reference
- 57028-96-3(CAS DataBase Reference)
Polyhexamethyleneguanidine hydrochloride Chemical Properties,Usage,Production
Description
Polyhexamethylene guanidine (PHMG) is a guanidine derivative that is used as a biocidal disinfectant, often in the form of its salt polyhexamethylene guanidine phosphate (PHMG-P).
Uses
Polyhexamethyleneguanidine Hydrochloride is an Ophthalmic compound containing Phenylephrine. Polyhexamethyleneguanidine Hydrochloride is an antibacterial agent; used in preparation method of multifuctional flame-retardant Polyester fabric.
Toxicity
Preliminary findings indicate that PHMG and its derivatives primarily rely on damaging the cell membrane by inhibiting the activity of cellular dehydrogenases.When PHMG is aerosolized and inhaled, it harms the lungs, causing death of the cells lining the bronchioles and widespread damage to alveoli, along with bronchiolitis obliterans,an often fatal form of non-reversible obstructive lung disease in which the bronchiole are compressed and narrowed by fibrosis (scar tissue) and/or inflammation.
Chemical Properties
Colorless to pale yellow solution
Uses
Polyhexamethyleneguanidine (PHMGH) hydrochloride is a positively charged polymer with broad-spectrum antimicrobial activity. It exerts its antibacterial effects by binding to the cell membranes of bacteria and fungi, disrupting membrane integrity. Polyhexamethyleneguanidine hydrochloride can be applied in studies related to disinfection, water treatment, pesticides, and other fields[1][2]
Application
The polymer structure of polyhexamethyleneguanidine hydrochloride (PHGC) reduces its toxicity. However, the sterilization effect is more excellent, and it has been widely used in various fields such as medical and health institutions, family life, food industry and animal husbandry.
References
[1] Wei D, et al. Structural characterization and antibacterial activity of oligoguanidine (polyhexamethylene guanidine hydrochloride)[J]. Materials Science and Engineering: C, 2009, 29(6): 1776-1780.
[2] Choi H, et al. Antifungal activity of the cationic antimicrobial polymer-polyhexamethylene guanidine hydrochloride and its mode of action[J]. Fungal biology, 2017, 121(1): 53-60. DOI:10.1016/j.funbio.2016.09.001
Polyhexamethyleneguanidine hydrochloride Preparation Products And Raw materials
Raw materials
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View Lastest Price from Polyhexamethyleneguanidine hydrochloride manufacturers
- Product
- Polyhexamethyleneguanidine hydrochloride 57028-96-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24
- Product
- Polyhexamethyleneguanidine hydrochloride (PHMG) 57028-96-3
- Price
- US $0.00/Kg/Drum
- Min. Order
- 100g
- Purity
- ≥99% ≥95% ≥55% ≥25%
- Supply Ability
- 2000mt
- Release date
- 2020-05-22
- Product
- Polyhexamethyleneguanidine hydrochloride 57028-96-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-09-23