ChemicalBook > CAS DataBase List > [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate

[(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate

Product Name: [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate
CAS No.: 1616-93-9
Chemical Name: [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate
Synonyms: β-Amyrin acetate;O-Acetyl-β-amyrin;β-Amyrenyl acetate;beta-Amyrin acetate;Erythrodiol 3-acetate;Olean-12-en-3β-ol acetate;AMYRIN ACETATE, BETA- (RG);Olean-12-en-3-ol,3-acetate, (3b)-;Olean-12-en-3-ol, 3-acetate, (3β)-;Acetic acid 5α-olean-12-en-3β-yl ester
CBNumber: CB81254491
Molecular Formula: C32H52O2
Formula Weight: 468.75
MOL File: 1616-93-9.mol

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[(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate Property

solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
color: White to off-white
LogP: 11.950 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN99679
Product name: beta-Amyrinacetate
Packaging: 5mg
Price: $138
Updated: 2021/12/16

Crysdot

Product number: CD32002284
Product name: β-Amyrinacetate
Purity: 95+%
Packaging: 5mg
Price: $170
Updated: 2021/12/16

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[(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate Chemical Properties,Usage,Production

Uses

β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase[1][2][3][4].

in vivo

β-Amyrin acetate (applied on the anterior surface of the right ear, 100 μg/ear, a single dose) significantly inhibits xylene-induced ear edema in mice^[1].
β-Amyrin acetate (intraperitoneal injection, 4 mg/100 g, daily for 6 consecutive days) shows significant anti-inflammatory activities (43.6%) in adult albino rats^[3].
β-Amyrin acetate (subcutaneous injection, 4 mg/100 g, daily for 10 days ) increases the ATP-phosphohydrolase activity in liver homogenates both in normal and arthritic rats^[3].

Animal Model:	Xylene-induced mouse ear topical edema model^[1]
Dosage:	50 and 100 μg/ear (5 μL)
Administration:	Applied on the anterior surface of the right ear
Result:	Inhibited Xylene-induced ear edema in mice

Animal Model:	Adult albino rats^[3]
Dosage:	4 mg/100g, daily for 6 consecutive days
Administration:	Intraperitoneal injection
Result:	Showed significant anti-inflammatory activities with mean average weight of granulation tissue of 9.2 mg after 6 days.

target

Immunology & Inflammation related

References

[1] Nkeoma Nkasi Okoye, et al. beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity. Pharm Biol. 2014 Nov;52(11):1478-86. DOI:10.3109/13880209.2014.898078
[2] Ranjani Maurya, et al. β-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves. Phytomedicine. 2012 Jun 15;19(8-9):682-5. DOI:10.1016/j.phymed.2012.03.013
[3] M.B.Gupta, et al. Biochemical study of the anti-inflammatory activity of α and β-amyrin acetate. Biochemical Pharmacology. 1971 Feb; 2(20): 401-405.
[4] S Johann, et al. Antifungal activity of the amyrin derivatives and in vitro inhibition of Candida albicans adhesion to human epithelial cells. Lett Appl Microbiol. 2007 Aug;45(2):148-53. DOI:10.1111/j.1472-765X.2007.02162.x

[(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate Preparation Products And Raw materials

Raw materials

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View Lastest Price from [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate manufacturers

Career Henan Chemical Co

Product: [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate 1616-93-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

1616-93-9, [(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetateRelated Search:

beta-Sitosterol alpha-Cyperone MOSLOFLAVONE Hydroxyecdysone alpha-Terpineol hydroxygenkwanin Artemether beta-Eudesmol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Erythrodiol

[(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl -1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate

Acetic acid 5α-olean-12-en-3β-yl ester

Erythrodiol 3-acetate

O-Acetyl-β-amyrin

Olean-12-en-3β-ol acetate

β-Amyrenyl acetate

beta-Amyrin acetate

AMYRIN ACETATE, BETA- (RG)

Olean-12-en-3-ol,3-acetate, (3b)-

β-Amyrin acetate

(4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl)acetate

HMG-CoA,betaAmyrin acetate,LDL,Fungal,inhibit,Inhibitor,arthritic,hemolysis,antifungal,anti-inflammatory,HMG-CoA Reductase (HMGCR),inflammation,β-Amyrin,beta Amyrin acetate

Olean-12-en-3-ol, 3-acetate, (3β)-

1616-93-9