ChemicalBook > CAS DataBase List > 4-Fluoro-3-methoxybenzonitrile

4-Fluoro-3-methoxybenzonitrile

Product Name
4-Fluoro-3-methoxybenzonitrile
CAS No.
243128-37-2
Chemical Name
4-Fluoro-3-methoxybenzonitrile
Synonyms
BUTTPARK 22\01-64;5-Cyano-2-fluoroanisole;4-Fluoro-3-methoxybenzonitri;3-methoxy-fluorobenzonitrile;4-FLUORO-3-METHOXYBENZONITRILE;3-Methoxy-4-Fluorobenzonitrile;Benzonitrile, 4-fluoro-3-methoxy-;4-Fluoro-3-methoxybenzonitrile99%;4-Fluoro-3-methoxybenzonitrile 99%;Benzonitrile, 4-fluoro-3-methoxy- (9CI)
CBNumber
CB8132169
Molecular Formula
C8H6FNO
Formula Weight
151.14
MOL File
243128-37-2.mol
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4-Fluoro-3-methoxybenzonitrile Property

Melting point:
109 °C
Boiling point:
96-98°C 1,5mm
Density 
1.18±0.1 g/cm3(Predicted)
Flash point:
96-98°C/1.5mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Toluene
form 
powder to crystal
color 
White to Light yellow to Light orange
BRN 
2965042
CAS DataBase Reference
243128-37-2(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi,Xn
Risk Statements 
20/21/22-36/37/38-22
Safety Statements 
26-36/37/39-36/37-9
RIDADR 
3439
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0408
Product name
4-Fluoro-3-methoxybenzonitrile
Packaging
1g
Price
$24
Updated
2025/07/31
TCI Chemical
Product number
F0408
Product name
4-Fluoro-3-methoxybenzonitrile
Packaging
5g
Price
$89
Updated
2025/07/31
Matrix Scientific
Product number
002363
Product name
4-Fluoro-3-methoxybenzonitrile
Purity
99%
Packaging
100g
Price
$180
Updated
2021/12/16
SynQuest Laboratories
Product number
4637-3-43
Product name
4-Fluoro-3-methoxybenzonitrile
Purity
99%
Packaging
25g
Price
$95
Updated
2021/12/16
Matrix Scientific
Product number
002363
Product name
4-Fluoro-3-methoxybenzonitrile
Purity
99%
Packaging
25g
Price
$50
Updated
2021/12/16
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4-Fluoro-3-methoxybenzonitrile Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

946713-86-6

57-13-6

243128-37-2

Cu(TFA)2 (20 mmol) was added to a pressure-sealed tube containing 0.75 mL of DMSO with 4-fluoro-3-methoxyphenylacetic acid (0.5 mmol) and urea (1.5 mmol). The reaction system was oxygenated and stirred at 130 °C for about 20 h. The reaction process was monitored by TLC and GC (the exact reaction time was determined based on GC and TLC monitoring results). Upon completion of the reaction, the reaction was cooled to room temperature. To the reaction mixture, 20 mL of ethyl acetate was added and washed sequentially with NaHCO3 solution (20 mL x 2) and water. The organic phases were combined and dried over anhydrous sodium sulfate. The aqueous phase was then extracted with ethyl acetate (20 mL x 2) and all organic phases were combined. The solvent was removed by rotary evaporator to obtain the crude product. The crude product was purified by silica gel column chromatography with the eluent ratio of ethyl acetate:petroleum ether=50:1. 4-fluoro-3-methoxybenzonitrile was finally obtained in 84% yield.

References

[1] Patent: CN103772236, 2016, B. Location in patent: Paragraph 0021; 0022; 0023; 0054; 0055; 0056; 0057

4-Fluoro-3-methoxybenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Fluoro-3-methoxybenzonitrile manufacturers

Career Henan Chemical Co
Product
4-Fluoro-3-methoxybenzonitri 243128-37-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10

243128-37-2, 4-Fluoro-3-methoxybenzonitrileRelated Search:

3-Methoxybenzoic acid Benzonitrile p-Tolunitrile p-Anisaldehyde 4-(Trifluoromethoxy)aniline m-Anisyl alcohol 4-Methoxyphenylacetic acid 3-(Trifluoromethoxy)bromobenzene Anisole 4-Nitrobenzonitrile 4-Methoxybenzyl alcohol 4-Methoxybenzoic acid Anisonitrile 2-Cyanophenol (Trifluoromethoxy)benzene 3-Methoxy-2,4-difluorobenzonitrile 4-FLUORO-3-(TRIFLUOROMETHOXY)BENZONITRILE Fluorine

  • BUTTPARK 22\01-64
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  • 4-Fluoro-3-methoxybenzonitrile 99%
  • 4-Fluoro-3-methoxybenzonitrile99%
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  • 3-methoxy-fluorobenzonitrile
  • 4-Fluoro-3-methoxybenzonitri
  • Benzonitrile, 4-fluoro-3-methoxy-
  • 243128-37-2
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  • HALIDE