5-BROMO-6-HYDROXYNICOTINIC ACID

Product Name: 5-BROMO-6-HYDROXYNICOTINIC ACID
CAS No.: 41668-13-7
Chemical Name: 5-BROMO-6-HYDROXYNICOTINIC ACID
Synonyms: 5-Bromo-6-Hydroxy Niacin;5-BROMO-6-HYDROXYNICOTINIC ACID;6-Hydroxy-5-bromonicotinic acid;3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE;5-Bromo-6-hydroxynicotinic acid 97%;5-Bromo-6-hydroxynicotinic acid ,97%;5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;5-bromo-6-oxo-1H-pyridine-3-carboxylic acid;5-Bromo-6-hydroxy-pyridin-3-carboxylic acid
CBNumber: CB8137629
Molecular Formula: C6H4BrNO3
Formula Weight: 218
MOL File: 41668-13-7.mol

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5-BROMO-6-HYDROXYNICOTINIC ACID Property

Melting point:: >300
Boiling point:: 348.1±42.0 °C(Predicted)
Density: 2.015±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 3.38±0.50(Predicted)
form: powder to crystal
color: White to Almost white
InChI: InChI=1S/C6H4BrNO3/c7-4-1-3(6(10)11)2-8-5(4)9/h1-2H,(H,8,9)(H,10,11)
InChIKey: PQDLYKZCJBGXPQ-UHFFFAOYSA-N
SMILES: C1NC(=O)C(Br)=CC=1C(O)=O

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
Hazard Note: Irritant/Keep Cold
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5193
Product name: 5-Bromo-6-hydroxynicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $57
Updated: 2025/07/31

TCI Chemical

Product number: B5193
Product name: 5-Bromo-6-hydroxynicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $172
Updated: 2025/07/31

TRC

Product number: B696223
Product name: 5-Bromo-6-hydroxynicotinic Acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0024564
Product name: 5-BROMO-6-HYDROXYNICOTINIC ACID
Purity: 95.00%
Packaging: 1G
Price: $642.99
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB147581
Product name: 5-Bromo-6-oxo-1,6-dihydro-3-pyridinecarboxylicacid
Packaging: 1g
Price: $283
Updated: 2021/12/16

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5-BROMO-6-HYDROXYNICOTINIC ACID Chemical Properties,Usage,Production

Chemical Properties

Light green solid

Synthesis

5006-66-6

41668-13-7

Synthesis of 5-bromo-6-hydroxynicotinic acid: 6-hydroxynicotinic acid (8 g, 57.6 mmol) was suspended in water (30 mL) and bromine (4.2 mL, 81.4 mmol) was slowly added under ice bath cooling conditions. After addition, the reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solid product was collected by filtration, washed with water and dried in a vacuum oven at 40 °C for 24 h to afford 5-bromo-6-hydroxynicotinic acid (12.1 g, 97% yield) as a tan solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.04 (d, J = 2.53 Hz, 1H), 8.16 (d, J = 2.27 Hz, 1H), 12.59 (br s, 1H), 12.90 (br s, 1H).

References

[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 24, p. 9874 - 9896
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 15, p. 4892 - 4909
[3] Patent: WO2007/70818, 2007, A1. Location in patent: Page/Page column 103
[4] Patent: WO2006/88919, 2006, A2. Location in patent: Page/Page column 134-135
[5] Patent: US2008/85906, 2008, A1. Location in patent: Page/Page column 15

5-BROMO-6-HYDROXYNICOTINIC ACID Preparation Products And Raw materials

Raw materials

2-Hydroxy-5-pyridinecarboxylic acid Bromine Sodium metabisulfite

Preparation Products

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5-BROMO-6-HYDROXYNICOTINIC ACID Suppliers

Americas 1 China 144 Czech Republic 1 Europe 1 Germany 4 India 9 Japan 1 United Kingdom 5 United States 16 Global 182

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View Lastest Price from 5-BROMO-6-HYDROXYNICOTINIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Henan Fengda Chemical Co., Ltd

Product: 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

41668-13-7, 5-BROMO-6-HYDROXYNICOTINIC ACIDRelated Search:

METHYL 5-BROMO-6-HYDROXYNICOTINATE ethyl 5-broMo-6-hydroxynicotinate 1,2,3,4-TETRAHYDROQUINOLIN-6-OL 6H-Pyrrolo[2,3-b]pyridin-6-one, 1,7-dihydro- 5-Iodo-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid Methyl ester 5-Bromonicotinic acid 5-BROMO-2-HYDROXYNICOTINIC ACID,5-Bromo-2-hydroxynicotinic acid 98%,5-BROMO-2-HYDROXYNICOTINIC ACID HPLC 99%,5-Bromo-2-hydroxynicotinic acid ,98% 5-BROMO-6-HYDROXYNICOTINIC ACID 5-bromo-6-(cyclopropylmethoxy)nicotinic acid 1-BENZYL-5-BROMO-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 5-bromo-6-(tetrahydro-2h-pyran-4-yloxy)nicotinic acid METHYL 5-BROMO-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE 5-bromo-6-(cyclohexyloxy)nicotinic acid 6-(2-aziridin-1-ylethoxy)-5-bromonicotinic acid ethyl 3-bromo-4-oxo-4H-quinolizine-1-carboxylate 5-bromo-6-(piperidin-4-yloxy)nicotinic acid 5-BROMO-2,6-DIMETHOXY-NICOTINIC ACID METHYL ESTER 5-bromo-6-(piperidin-4-ylmethoxy)nicotinic acid

5-Bromo-6-hydroxynicotinic acid ,97%

6-Hydroxy-5-bromonicotinic acid

5-broMo-6-oxo-1,6-dihydropyridine-3-carboxylic acid

5-broMo-1,6-dihydro-6-oxo-3-Pyridinecarboxylic acid

5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID

5-BROMO-6-HYDROXYNICOTINIC ACID

5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID

3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE

5-Bromo-6-hydroxynicotinic acid 97%

3-Pyridinecarboxylic acid, 5-bromo-1,6-dihydro-6-oxo-

5-BROMO-6-HYDROXYNICOTINIC ACID ISO 9001：2015 REACH

5-bromo-6-oxo-1H-pyridine-3-carboxylic acid

5-Bromo-6-Hydroxy Niacin

5-Bromo-6-hydroxy-pyridin-3-carboxylic acid

41668-13-7

Carboxylic Acids

blocks

Bromides

Carboxes

Pyridines

Carboxylic Acids

API intermediates

Pyridine