1-Fluoro-2-iodobenzene

Product Name: 1-Fluoro-2-iodobenzene
CAS No.: 348-52-7
Chemical Name: 1-Fluoro-2-iodobenzene
Synonyms: 2-FLUOROIODOBENZENE;CL055;uoroiodobenzene;2-Fluoriodobenzene;2-iodofluorobenzene;O-FLUOROIODOBENZENE;O-IODO FLUOROBENZENE;1-fluor-2-oiodobenzene;1-FLUORO-2-IODOBENZENE;1-fluoro-2-iodo-benzen
CBNumber: CB8138383
Molecular Formula: C6H4FI
Formula Weight: 222
MOL File: 348-52-7.mol

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1-Fluoro-2-iodobenzene Property

Melting point:: −41-−40 °C(lit.)
Boiling point:: 188-189 °C(lit.)
Density: 1.903 g/mL at 25 °C(lit.)
refractive index: n20/D 1.59(lit.)
Flash point:: 160 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Liquid
Specific Gravity: 1.903
color: Clear light yellow
Sensitive: Light Sensitive
BRN: 2039770
CAS DataBase Reference: 348-52-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1-fluoro-2-iodo-(348-52-7)
EPA Substance Registry System: o-Fluoroiodobenzene (348-52-7)

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Safety

Hazard Codes: Xn,N,Xi
Risk Statements: 22-37/38-41-51/53-36/37/38
Safety Statements: 26-39-61-37/39
RIDADR: UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)
WGK Germany: 2
TSCA: T
HazardClass: IRRITANT
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 219401
Product name: 2-Fluoroiodobenzene
Purity: 99%, contains copper as stabilizer
Packaging: 25g
Price: $93.4
Updated: 2023/06/20

TCI Chemical

Product number: F0253
Product name: 1-Fluoro-2-iodobenzene
Purity: >99.0%(GC)
Packaging: 10g
Price: $19
Updated: 2025/07/31

TCI Chemical

Product number: F0253
Product name: 1-Fluoro-2-iodobenzene
Purity: >99.0%(GC)
Packaging: 25g
Price: $33
Updated: 2025/07/31

TRC

Product number: F591990
Product name: 2-Fluoroiodobenzene
Packaging: 50g
Price: $120
Updated: 2021/12/16

Apolloscientific

Product number: PC3760
Product name: 2-Fluoroiodobenzene
Purity: 99%
Packaging: 500g
Price: $183
Updated: 2021/12/16

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1-Fluoro-2-iodobenzene Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to light yellow liquid

Uses

suzuki reaction

Uses

2-Fluoroiodobenzene was used in the synthesis of:

bridged biphenyl compounds, 1-fluoro-8-methylbiphenylene and 4-fluoro-5-methylfluorene
2-acetyl-7-iodo-1-benzothiophene
chiral o-phosphanophenyl sulfoxides

Synthesis Reference(s)

Synthetic Communications, 20, p. 1701, 1990 DOI: 10.1080/00397919008053092

Synthesis

445-29-4

348-52-7

Cesium carbonate (Cs2CO3) (0.6 mmol, 195 mg), o-fluorobenzoic acid (1) (0.3 mmol), photocatalyst [Ir(dF(CF3)ppy)2dtbbpy]PF6(D) (6 μmol, 6.7 mg), N-iodosuccinimide (NIS) (0.9 mmol, 202.5 mg) and iodine (I2) (15 μmol, 5 mol%) were added in order to a 15 mL test tube. 202.5 mg) and iodine (I2) (15 μmol, 5 mol%). The tubes were evacuated and displaced three times with argon, followed by the addition of 3 mL of anhydrous 1,2-dichloroethane (DCE) via syringe under argon protection. The tubes were sealed with Parafilm M, placed in an oil bath fitted with a contact thermometer, and the reaction was carried out at 50 °C by irradiation with a 6 × 5 W blue LED (λmax = 455 nm). After 24 or 36 h of reaction, the reaction mixture was filtered through a 2 cm thick pad of silica gel and the silica gel was washed with dichloromethane (DCM) (50 mL). The filtrates were combined and concentrated under reduced pressure to remove the solvent. The crude product was purified by rapid column chromatography on silica gel to afford the target product o-fluoroiodobenzene (2). (Note: The reaction is extremely sensitive to moisture, and the product yield was significantly reduced to less than 5% when 0.01 equivalents of water was added to the system.)

References

[1] Synlett, 2018, vol. 29, # 12, p. 1572 - 1577

1-Fluoro-2-iodobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

2-FLUOROPHENYLBORONIC ACID 2-Fluorophenylboronic acid

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1-Fluoro-2-iodobenzene Suppliers

Americas 1 Belgium 2 China 276 Europe 4 France 1 Germany 3 India 15 Italy 1 Japan 4 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 37 Global 368

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Shijiazhuang Sdyano Fine Chemical Co., Ltd.

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Wuhan Chemwish Technology Co., Ltd

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Capot Chemical Co., Ltd

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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
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ProdList: 9976
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View Lastest Price from 1-Fluoro-2-iodobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1-Fluoro-2-iodobenzene 348-52-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 MT
Release date: 2024-11-08

Henan Fengda Chemical Co., Ltd

Product: 1-Fluoro-2-iodobenzene 348-52-7
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Fluoro-2-iodobenzene 348-52-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

348-52-7, 1-Fluoro-2-iodobenzeneRelated Search:

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1-fluoro-2-iodo-benzen

O-FLUOROIODOBENZENE

O-IODO FLUOROBENZENE

uoroiodobenzene

2-Fluoroiodobenzene 99%, contains copper as stabilizer

1-Fluoro-2-iodobenzene, Stabilized with copper

CL055

2-FLUOROIODOBENZENE

1-FLUORO-2-IODOBENZENE

1-fluor-2-oiodobenzene

2-iodofluorobenzene

1-Fluoro-2-iodobenzene,99%

Benzene, 1-fluoro-2-iodo-

2-Fluoroiodobenzene 99%

2-Fluoroiodobenzene99%

1-Fluoro-2-iodobenzene, 99% 5ML

1-Iodo-2-fluorobenzene

2-Fluoro-1-iodobenzene

1-Fluoro-2-iodobenzene, 99%, stab. with copper

1-Fluoro-2-iodobenzene&gt

2-Fluoriodobenzene

1-Fluoro-2-iodobenzene ISO 9001：2015 REACH

2-Fluoroiodobenzene,contains copper as stabilizer

Ortho fluoroiodobenzene

1-fluoro-2-iodobenzene - [F86543]

348-52-7

348-52-8

3248-52-7

FC6H4I

HALOGEN

Aryl

Building Blocks

Organic Building Blocks

Halogenated Hydrocarbons

C6

Aryl Fluorinated Building Blocks

Building Blocks

Chemical Synthesis

Fluorinated Building Blocks

Halogenated Hydrocarbons

Organic Building Blocks

Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

Aromatic Esters

Fluorobenzene

Miscellaneous

Fluorine Compounds

Iodine Compounds

Aryl

Halogenated Hydrocarbons

C6