ChemicalBook > CAS DataBase List > 2-Methyl-3-amino-4-acetylanisole

2-Methyl-3-amino-4-acetylanisole

Product Name: 2-Methyl-3-amino-4-acetylanisole
CAS No.: 912347-94-5
Chemical Name: 2-Methyl-3-amino-4-acetylanisole
Synonyms: 2-methyl-3-amino-4-acetylanisole;6-ACETYL-3-METHOXY-2-METHYL ANILINE;1-(2-aMino-4-Methoxy-3-Methylphenyl)-;2-AMino-4-Methoxy-3-Methylacetophenone;2-Amino-4-methoxy-3-methylbenzoic acid;(2-Amino-3-methyl-4-methoxyphenyl)acetone;2'-Amino-3'-methyl-4'-methoxyacetophenone;2-Methyl-3-amino-4-acetylanisole USP/EP/BP;1-(2-Amino-4-methoxy-3-methylphenyl)ethanone;1-(2-aMino-4-Methoxy-3-Methylphenyl)ethan-1-one
CBNumber: CB81465767
Molecular Formula: C10H13NO2
Formula Weight: 179.22
MOL File: 912347-94-5.mol

Less

2-Methyl-3-amino-4-acetylanisole Property

Melting point:: 107 °C
Boiling point:: 336.0±37.0 °C(Predicted)
Density: 1.096±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 1.74±0.10(Predicted)
color: White to Yellow to Orange
InChI: InChI=1S/C10H13NO2/c1-6-9(13-3)5-4-8(7(2)12)10(6)11/h4-5H,11H2,1-3H3
InChIKey: VXBGCEDOGYNWHE-UHFFFAOYSA-N
SMILES: C(=O)(C1=CC=C(OC)C(C)=C1N)C

Less

Safety

HS Code: 2922500090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: A3027
Product name: 2'-Amino-3'-methyl-4'-methoxyacetophenone
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $90
Updated: 2025/07/31

TCI Chemical

Product number: A3027
Product name: 2'-Amino-3'-methyl-4'-methoxyacetophenone
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $312
Updated: 2025/07/31

TRC

Product number: A613115
Product name: 1-(2-Amino-4-methoxy-3-methylphenyl)ethanone
Packaging: 500mg
Price: $115
Updated: 2021/12/16

TRC

Product number: A613115
Product name: 1-(2-Amino-4-methoxy-3-methylphenyl)ethanone
Packaging: 1g
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-B0016
Product name: Ethanone,1-(2-amino-4-methoxy-3-methylphenyl)-
Purity: ≥98.0%
Packaging: 5g
Price: $141
Updated: 2021/12/16

Less

2-Methyl-3-amino-4-acetylanisole Chemical Properties,Usage,Production

Synthesis

75-05-8

19500-02-8

912347-94-5

To a solution of 2-methyl-3-methoxyaniline (5.0 g, 36.5 mmol) in p-xylene (80 mL) was cooled to 0 °C, and a dichloromethane solution (36.5 mL) of 1 M BCl3 was slowly added. The reaction mixture was stirred at 0 °C for 30 min under nitrogen protection. Subsequently, acetonitrile (2.6 mL, 54.7 mmol) was added and stirring was continued at 0 °C for 30 min. In another reaction flask, AlCl3 (4.87 g, 36.5 mmol) was suspended in anhydrous dichloromethane (50 mL), cooled to 0 °C, and the aforementioned p-xylene solution was added dropwise through the addition funnel under nitrogen protection. After addition, the dichloromethane was removed under vacuum after stirring at 0°C for 45 minutes. The remaining p-xylene solution was heated to 70°C and maintained for 18 hours, followed by cooling to room temperature. Water (80 mL) was added and again heated to 70°C maintained for 1 hour and cooled to room temperature. The reaction mixture was diluted with ethyl acetate and the aqueous layer was separated. The organic layer was washed sequentially with equal volumes of water and saturated saline, dried over anhydrous MgSO4 and concentrated under reduced pressure. 1H), 7.03 (br.s., 2H), 7.65 (d, J = 9.04 Hz, 1H). LC-MS (ESI): m/z 180.10 (M + H)+.

References

[1] Patent: US2010/196321, 2010, A1. Location in patent: Page/Page column 20
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3021 - 3026
[3] Patent: WO2008/96002, 2008, A1. Location in patent: Page/Page column 82-83
[4] Patent: WO2008/92954, 2008, A2. Location in patent: Page/Page column 28-29
[5] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 17, p. 4853 - 4858

2-Methyl-3-amino-4-acetylanisole Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-Methyl-3-amino-4-acetylanisole Suppliers

Americas 1 Canada 1 China 107 Europe 1 India 3 Japan 1 United Kingdom 1 United States 10 Global 125

ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD

Tel: 18957127338 18305707819;
Email: sales@zetchem.com
Country: China
ProdList: 500
Advantage: 58

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Boc Chemical Co.,Ltd

Tel: 021-34975603-808 18721111801
Fax: +86-21-34975602-805
Email: sales@bocpharma.com
Country: China
ProdList: 1009
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527621225
Email: 1791901229@qq.com
Country: China
ProdList: 6949
Advantage: 52

PSN Pharmaceutical Technology Co., Ltd.

Tel: 86-25-57062118
Fax: 86-25-57065896
Email: sales@jspsn.com
Country: China
ProdList: 496
Advantage: 57

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

DanYang Ruihui Chemical Co.,Ltd

Tel: 0511-86883198
Fax: 0511-86983963
Email: sales@rhchemical.com
Country: China
ProdList: 33
Advantage: 58

SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD

Tel: 13816107857
Fax: qq: 276312098
Email: sales@fortunechem-sh.com
Country: China
ProdList: 984
Advantage: 58

Sinfachem Limited

Tel: 025-84683399 13952017251
Fax: 025-84683112
Email: sales@sinfachem.com
Country: China
ProdList: 217
Advantage: 56

Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-86818997 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2966
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ChongQing Purel Bio-Pharmaceutical Technology Co., Ltd.

Tel: 023-89130144 18523560356
Fax: 023-67534737
Email: zhyong1011@163.com
Country: China
ProdList: 290
Advantage: 58

Hangzhou Dechem Tech Co.，Ltd

Tel: 86-0571-87649320
Fax: 86-0571-87649320
Email: dechem@aliyun.com
Country: China
ProdList: 162
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Nanjing Duolong Bio-tech Co.,Ltd.

Tel: 18905173768
Fax: 025-83263139
Email: 52513593@qq.com
Country: China
ProdList: 2331
Advantage: 50

shanghai sinofluoro chemicals co., ltd.

Tel: 15800445152
Fax: 021-64278603
Email: sales@sinofluoro.com
Country: China
ProdList: 297
Advantage: 59

AN PharmaTech Co Ltd

Tel: 86(21)68097365
Fax: 86(21)33321566
Email: sales@anpharma.net
Country: China
ProdList: 4891
Advantage: 55

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Advanced carbon Organic Pharm Co., Ltd.

Tel: +86-021-60528262
Fax: +86-021-64306513
Email: sales@acopharm.com
Country: China
ProdList: 94
Advantage: 58

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai Sainty Biotechnology Co., Ltd.

Tel: 021-58957915 17721108391
Fax: QQ: 907522080
Email: 907522080@qq.com
Country: China
ProdList: 997
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

Shanghai Shanyuan pharmaceutical technology co., LTD

Tel: 021-31761238 13167072949
Fax: 021-31761238
Email: 3146446224@qq.com
Country: China
ProdList: 1379
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886750 13927877953
Fax: 0751-2886750
Email: 3005811397@qq.com
Country: China
ProdList: 13305
Advantage: 58

Nanjing Klender Bio-Technology Co., Ltd.

Tel: 025-52343882 18112933882
Fax: 025-52343882
Email: sales@kldbio.com
Country: China
ProdList: 2019
Advantage: 55

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Beijing Bankchem Pharmatech Co.,Ltd.

Tel: 010-80236392 17600588818
Fax: qq:1210787803
Email: bankchem@163.com
Country: China
ProdList: 311
Advantage: 58

Hubei Changrun Biomedical Technology Co., Ltd.

Tel: 027-63496417 13007129042
Fax: 13476107660
Email: 3294393103@qq.com
Country: China
ProdList: 295
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

Less

View Lastest Price from 2-Methyl-3-amino-4-acetylanisole manufacturers

Career Henan Chemical Co

Product: 2-Methyl-3-amino-4-acetylanisole 912347-94-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KG
Release date: 2019-09-04

912347-94-5, 2-Methyl-3-amino-4-acetylanisoleRelated Search:

Methanol Kresoxim-methyl 4-Acetylbenzoic acid Paraquat dichloride Methylparaben Basic Violet 1 4-Methylanisole ALTRENOGEST Lithium bis(trimethylsilyl)amide Acetonitrile N,N-Dimethyl-1,4-phenylenediamine 2-Methyl-3-nitroanisole 2-Methoxyethanol L-PICEIN DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Methyl acetate Tris(hydroxymethyl)aminomethane Methyl acrylate

1-(2-Amino-4-methoxy-3-methylphenyl)ethanone 97%

Ethanone, 1-(2-amino-4-methoxy-3-methylphenyl)-

2-methyl-3-amino-4-acetylanisole

1-(2-Amino-4-methoxy-3-methylphenyl)ethanone

6-ACETYL-3-METHOXY-2-METHYL ANILINE

2-Amino-4-methoxy-3-methylbenzoic acid

1-(2-aMino-4-Methoxy-3-Methylphenyl)-

1-(2-aMino-4-Methoxy-3-Methylphenyl)ethan-1-one

2'-Amino-3'-methyl-4'-methoxyacetophenone

2-AMino-4-Methoxy-3-Methylacetophenone

(2-Amino-3-methyl-4-methoxyphenyl)acetone

2-Methyl-3-amino-4-acetylanisole USP/EP/BP

912347-94-5

Amino Acid Derivatives

Drug Intermediates

Multisubstituted Benzene