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6-HYDROXY-3-PYRIDINEBORONIC ACID

Product Name
6-HYDROXY-3-PYRIDINEBORONIC ACID
CAS No.
903899-13-8
Chemical Name
6-HYDROXY-3-PYRIDINEBORONIC ACID
Synonyms
5-BORONO-2-PYRIDONE;6-HYDROXY-3-PYRIDINEBORONIC ACID;2-Hydroxypyridine-5-boronic acid;(6-Hydroxy-3-pyridyl)boronic acid;(6-oxo-1H-pyridin-3-yl)boronic acid;1,6-Dihydro-6-oxopyridine-3-boronic acid;(6-oxo-5,6-dihydropyridin-3-yl)boronic acid;(6-oxo-1,6-dihydropyridin-3-yl)boronic acid;B-(1,6-dihydro-6-oxo-3-pyridinyl)-Boronic acid;(6-Hydroxypyridin-3-yl)boronic acid - [H26341]
CBNumber
CB81486760
Molecular Formula
C5H6BNO3
Formula Weight
138.92
MOL File
903899-13-8.mol
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6-HYDROXY-3-PYRIDINEBORONIC ACID Property

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml,Ethanol: 1 mg/ml
form 
A crystalline solid
pka
8.02±0.20(Predicted)
color 
White to off-white
InChI
InChI=1S/C5H6BNO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3,9-10H,(H,7,8)
InChIKey
YUOLAYZNDYRBEZ-UHFFFAOYSA-N
SMILES
B(C1C=CC(=O)NC=1)(O)O
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Safety

RIDADR 
2811
HazardClass 
6.1
PackingGroup 
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30492
Product name
6-Hydroxypyridin-3-ylboronic Acid
Packaging
100mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
30492
Product name
6-Hydroxypyridin-3-ylboronic Acid
Packaging
500mg
Price
$239
Updated
2024/03/01
Cayman Chemical
Product number
30492
Product name
6-Hydroxypyridin-3-ylboronic Acid
Packaging
250mg
Price
$135
Updated
2024/03/01
TRC
Product number
D449273
Product name
1,6-Dihydro-6-oxopyridine-3-boronicacid
Packaging
250mg
Price
$75
Updated
2021/12/16
Synthonix
Product number
H26341
Product name
(6-Hydroxypyridin-3-yl)boronicacid
Purity
97%
Packaging
250mg
Price
$70
Updated
2021/12/16
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6-HYDROXY-3-PYRIDINEBORONIC ACID Chemical Properties,Usage,Production

Uses

6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors[1][2].

References

[1] Hendricks RT, et al. 3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):410-4. DOI:10.1016/j.bmcl.2008.11.060
[2] Verheijen JC, et al. Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent. J Med Chem. 2009 Dec 24;52(24):8010-24. DOI:10.1021/jm9013828

6-HYDROXY-3-PYRIDINEBORONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-HYDROXY-3-PYRIDINEBORONIC ACID Suppliers

Atop Bio-Tech (Tianjin) Co., Ltd. (Atop)
Tel
022-66200236 18622210341
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+86-022-66200236
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sales@atop-biotech.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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United States
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Tetranov Biopharm
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China
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Accela ChemBio Co.,Ltd.
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Shanghai Longsheng chemical Co.,Ltd.
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021-58099609
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China
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
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(1)02557626880
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cfzhang@aikonchem.com
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China
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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View Lastest Price from 6-HYDROXY-3-PYRIDINEBORONIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-HYDROXY-3-PYRIDINEBORONIC ACID 903899-13-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-HYDROXY-3-PYRIDINEBORONIC ACID 903899-13-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09