4-Methylthiazole-5-carboxaldehyde

Product Name: 4-Methylthiazole-5-carboxaldehyde
CAS No.: 82294-70-0
Chemical Name: 4-Methylthiazole-5-carboxaldehyde
Synonyms: MFTA;FMT;F2124-0219;IFLAB-BB F2124-0219;4-METHYL-5-FORMYLTHIAZOLE;5-FORMYL-4-METHYLTHIAZOLE;4-METHYLTHIAZOLE-5-ALDEHYDE;4-Methyl-5-thiazole aldehyde;4-METHYL-5-THIAZOLYL ALDEHYDE;MFTA 4-Methyl-5-formylthiazole
CBNumber: CB8162850
Molecular Formula: C5H5NOS
Formula Weight: 127.16
MOL File: 82294-70-0.mol

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4-Methylthiazole-5-carboxaldehyde Property

Melting point:: 74-78 °C (lit.)
Boiling point:: 118°C/21mmHg(lit.)
Density: 1.270±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 1.53±0.10(Predicted)
color: White to Light yellow to Light orange
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C5H5NOS/c1-4-5(2-7)8-3-6-4/h2-3H,1H3
InChIKey: JJVIEMFQPALZOZ-UHFFFAOYSA-N
SMILES: S1C(C=O)=C(C)N=C1
LogP: 0.320 (est)
CAS DataBase Reference: 82294-70-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 41-43
Safety Statements: 26-39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29341000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 633208
Product name: 4-Methylthiazole-5-carboxaldehyde
Purity: 97%
Packaging: 1g
Price: $31.6
Updated: 2023/06/20

Sigma-Aldrich

Product number: 633208
Product name: 4-Methylthiazole-5-carboxaldehyde
Purity: 97%
Packaging: 5g
Price: $128
Updated: 2023/06/20

TCI Chemical

Product number: M1812
Product name: 4-Methylthiazole-5-carboxaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: M1812
Product name: 4-Methylthiazole-5-carboxaldehyde
Purity: >98.0%(GC)
Packaging: 5g
Price: $93
Updated: 2025/07/31

TRC

Product number: M331443
Product name: 4-Methylthiazole-5-carboxaldehyde
Packaging: 10g
Price: $155
Updated: 2021/12/16

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4-Methylthiazole-5-carboxaldehyde Chemical Properties,Usage,Production

Uses

4-Methylthiazole-5-carboxaldehyde is used as pharmaceutical intermediate.

Synthesis

89021-10-3

82294-70-0

General procedure for the synthesis of 4-methyl-5-thiazolecarboxaldehyde from 2-amino-4-methylthiazole-5-carboxaldehyde: A solution of tetrahydrofuran (THF, 3 mL) with amine 2 (5 mmol) was slowly added dropwise over a period of 20 min to a solution of tetrahydrofuran (THF, 3 mL) containing tert-butyl nitrite (t-BuONO, 7.5 mmol) and dimethylsulfoxide (DMSO, 0.5 mmol) in a solution of THF (7 mL). The reaction mixture was stirred continuously at 30°C until complete consumption of feedstock 2 was confirmed by thin layer chromatography (TLC) monitoring. Subsequently, the solvent was removed by evaporation and the yield of the low-boiling products was determined by gas chromatography (GC); the high-boiling products were separated and purified by silica gel column chromatography (eluent: hexane/ethyl acetate solvent mixture).

References

[1] Journal of Chemical Research, 2018, vol. 42, # 11, p. 579 - 583

4-Methylthiazole-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methylthiazole-5-carboxaldehyde Suppliers

Americas 1 Canada 3 China 267 Europe 4 Germany 3 India 11 Japan 2 Slovakia 2 Switzerland 1 Ukraine 1 United Kingdom 11 United States 38 Global 344

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View Lastest Price from 4-Methylthiazole-5-carboxaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Methylthiazole-5-carboxaldehyde 82294-70-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100
Release date: 2024-11-19

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Methylthiazole-5-carboxaldehyde 82294-70-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-05

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Methylthiazole-5-carboxaldehyde 82294-70-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

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MFTA

4-Methyl-5-thiazole aldehyde

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4-Methylthiazole-5-carboxaldehyde, 98%

82294-70-0

C5H4NOS

Heterocyclic Building Blocks

Thiazoles

Building Blocks

Thiazoles, Isothiazoles & Benzothiazoles

Building Blocks

Heterocyclic Building Blocks

Thiazoles

heterocyclic/Aliphatic series

ALDEHYDE

Aldehydes

Thiazoles, Isothiazoles &Benzothiazoles

1