ChemicalBook > CAS DataBase List > (R)-3-Amino-1-benzylpiperidine

(R)-3-Amino-1-benzylpiperidine

Product Name
(R)-3-Amino-1-benzylpiperidine
CAS No.
168466-84-0
Chemical Name
(R)-3-Amino-1-benzylpiperidine
Synonyms
C-3101R;CAS:168466-84-0;Linagliptin Impurity 89;(R)-1-benzylpiperidin-3-amine;(R)-1-BENZYL-3-AMINOPIPERIDINE;(R)-3-AMINO-1-BENZYL-PIPERIDINE;(r)-n-benzyl-3-amino-piperidine;1-BENZYL-PIPERIDIN-(R)-3-YLAMINE;(R)-1-BENZYL-PIPERIDIN-3-YLAMINE;(3R)-1-(Benzyl)-3-piperidinaMine
CBNumber
CB8175940
Molecular Formula
C12H18N2
Formula Weight
190.28
MOL File
168466-84-0.mol
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(R)-3-Amino-1-benzylpiperidine Property

Boiling point:
281.2±33.0 °C(Predicted)
Density 
1.037±0.06 g/cm3(Predicted)
Flash point:
113℃
storage temp. 
2-8°C(protect from light)
form 
solid
pka
10.21±0.20(Predicted)
color 
Yellow
Water Solubility 
Slightly soluble in water.
CAS DataBase Reference
168466-84-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
25-36/37/38
Safety Statements 
45-37-26
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A618623
Product name
(R)-3-Amino-1-benzylpiperidine
Packaging
100mg
Price
$60
Updated
2021/12/16
Activate Scientific
Product number
AS35716
Product name
(R)-3-Amino-1-benzylpiperidine
Purity
98+% ee
Packaging
5G
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA155125
Product name
(R)-3-Amino-1-benzylpiperidine
Packaging
2g
Price
$170
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA155125
Product name
(R)-3-Amino-1-benzylpiperidine
Packaging
5G
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA155125
Product name
(R)-3-Amino-1-benzylpiperidine
Packaging
1g
Price
$100
Updated
2021/12/16
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(R)-3-Amino-1-benzylpiperidine Chemical Properties,Usage,Production

Chemical Properties

White powder or yellow liquid

Uses

(R)-3-Amino-1-benzylpiperidine is used as an organic chemical synthesis intermediate.

Synthesis

168466-80-6

168466-84-0

Example 33: Preparation of (R)-1-benzyl-3-aminopiperidine (R)-1-benzylpiperidinamide (1.1 g) described in Example 2 was used as a starting material, which was mixed with water (5 mL), 30% aqueous sodium hydroxide (6.7 g, 10 eq.), tetrahydrofuran (THF, 10 mL), and an aqueous sodium hypochlorite solution (11.2 g, 1.5 eq.). The reaction mixture was stirred at 15°C for 1 hour, then warmed to 60°C and continued stirring for 2 hours. Upon completion of the reaction, the mixture was cooled to 20 °C and extracted three times with toluene (10 mL). After combining the organic layers, the solvent was removed by concentration under reduced pressure to afford the target product (R)-3-amino-1-benzylpiperidine as a yellow-brown oil (0.8 g, yield: 55%).

References

[1] Patent: US2010/105917, 2010, A1. Location in patent: Page/Page column 21

(R)-3-Amino-1-benzylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-3-Amino-1-benzylpiperidine Suppliers

China 118 Germany 1 India 3 United Kingdom 7 United States 19 Global 148
Carbosynth
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Fluorochem Ltd
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Fluorochem Ltd.
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Fulcrum Scientific Ltd.
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View Lastest Price from (R)-3-Amino-1-benzylpiperidine manufacturers

Career Henan Chemical Co
Product
(R)-3-Amino-1-benzylpiperidine 168466-84-0
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 375
Release date
2019-09-01

168466-84-0, (R)-3-Amino-1-benzylpiperidineRelated Search:

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  • (R)-3-AMINO-1-BENZYL-PIPERIDINE
  • (R)-1-BENZYL-PIPERIDIN-3-YLAMINE
  • (R)-1-BENZYL-3-AMINOPIPERIDINE
  • 1-BENZYL-PIPERIDIN-(R)-3-YLAMINE
  • C-3101R
  • 1-Benzyl-3-aMinopiperidine 98% EE99%
  • (3R)-1-(Benzyl)-3-piperidinaMine
  • (r)-n-benzyl-3-amino-piperidine
  • (R)-1-benzylpiperidin-3-amine
  • (3R)-3-Amino-1-benzylpiperidine, {[(3R)-3-Aminopiperidin-1-yl]methyl}benzene
  • (R)-1-Benzyl-3-aMinopiperidine, ee: 98%
  • (R)-1-benzylpiperidin-3-amine dihydrochloride
  • (3R)-1-(Phenylmethyl)-3-piperidinamine
  • (R)-1-Benzyl-3-aminopiperidine, 98%, ee: 98%
  • (R)-1-benzylpiperidin-3-aMine hydrochloride
  • (R)-3-Amino-1-benzylpiperidine,97%
  • 3-Piperidinamine, 1-(phenylmethyl)-, (3R)-
  • Linagliptin Impurity 89
  • CAS:168466-84-0
  • (R)-3-Amino-1-benzyl-piperidine, CAS 168466-84-0
  • 168466-84-0
  • Piperidine