4-Bromo-2-(trifluoromethyl)phenol
- Product Name
- 4-Bromo-2-(trifluoromethyl)phenol
- CAS No.
- 50824-04-9
- Chemical Name
- 4-Bromo-2-(trifluoromethyl)phenol
- Synonyms
- 5-Bromo-2-hydroxyBenzotrifluoride;4-BROMO-2-(TRIFLUOROMETHYL)PHENOL;4-BroMo-2-(trifluoroMethyl)phenol4;4-BROMO-2-(TRIFLUOROMETHYL)BENZENOL;4-Beromo-2-(trifluoromethyl)benzenol;Phenol, 4-bromo-2-(trifluoromethyl)-;4-Bromo-2-(trifluoromethyl)phenol >5-Bromo-2-hydroxybenzotrifluoride 99%;4-broMo -2-three fluorineMethyl phenol;4-Bromo-2-(trifluoromethyl)phenol, 4-Bromo-alpha,alpha,alpha-trifluoro-o-cresol
- CBNumber
- CB8179670
- Molecular Formula
- C7H4BrF3O
- Formula Weight
- 241.01
- MOL File
- 50824-04-9.mol
4-Bromo-2-(trifluoromethyl)phenol Property
- Melting point:
- 83-85°
- Boiling point:
- 203.4±35.0 °C(Predicted)
- Density
- 1.752±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 7.41±0.43(Predicted)
- form
- Crystalline Powder
- color
- White
- InChI
- InChI=1S/C7H4BrF3O/c8-4-1-2-6(12)5(3-4)7(9,10)11/h1-3,12H
- InChIKey
- PDPGERGWEOJVDC-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=C(Br)C=C1C(F)(F)F
Safety
- Hazard Codes
- T
- HazardClass
- IRRITANT
- HS Code
- 2908190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- KOB0023
- Product name
- 4-Bromo-2-(trifluoromethyl)benzenol
- Packaging
- 1 g
- Price
- $179
- Updated
- 2025/07/31
- Product number
- B4493
- Product name
- 4-Bromo-2-(trifluoromethyl)phenol
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- B4493
- Product name
- 4-Bromo-2-(trifluoromethyl)phenol
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $236
- Updated
- 2025/07/31
- Product number
- B695958
- Product name
- 4-Bromo-2-trifluoromethylphenol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB67200
- Product name
- 4-Bromo-2-(trifluoromethyl)phenol
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
4-Bromo-2-(trifluoromethyl)phenol Chemical Properties,Usage,Production
Chemical Properties
light yellow crystalline
Synthesis
444-30-4
50824-04-9
General procedure for the synthesis of 4-bromo-2-trifluoromethylphenol from o-trifluoromethylphenol: o-trifluoromethylphenol (6.0 g, 37 mmol) was dissolved in trifluoroacetic acid (30 ml), then bromine (5.91 g, 37 mmol) was added slowly and dropwise at room temperature. The reaction mixture was stirred for 2 hours. After completion of the reaction, ethyl acetate (200 ml) was added for extraction. The organic phase was washed sequentially with brine (50 mL x 2), saturated sodium carbonate solution (50 mL x 2) and brine (50 ml), and then dried with anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give 4-bromo-2-trifluoromethylphenol (gray solid, 8.9 g, yield: 100%).
References
[1] Patent: CN105732602, 2016, A. Location in patent: Paragraph 0094; 0096; 0097; 0098; 0099
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 5, p. 2107 - 2120
[3] Patent: WO2014/209034, 2014, A1. Location in patent: Paragraph 541; 542; 543
[4] Synthesis, 1999, # 11, p. 1878 - 1880
[5] Bulletin of the Chemical Society of Japan, 2004, vol. 77, # 12, p. 2257 - 2263
4-Bromo-2-(trifluoromethyl)phenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-2-(trifluoromethyl)phenol Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
View Lastest Price from 4-Bromo-2-(trifluoromethyl)phenol manufacturers
- Product
- 4-Bromo-2-(trifluoromethyl)phenol 50824-04-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02