2-Methoxy-3-(trifluoromethyl)pyridine
storage Uses- Product Name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- CAS No.
- 121643-44-5
- Chemical Name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Synonyms
- BUTTPARK 45\01-90;METHOXY-3-TRIFLUOROMETHYLPYRIDINE;2-Bromo-7-(trifluoromethyl)pyridine;2-METHOXY-3-(TRIFLUOROMETHYL)PYRIDINE;3-(trifluoroMethyl)-2-Methoxypyridine;2-Methoxy-3-(trifluoromethyl)pyridine>2-Methoxy-3-(trifluoromethyl)pyridine98%;2-Methoxy-3-(trifluoromethyl)pyridine 98%;2-Methoxy-3-(trifluoromethyl)pyridine ISO 9001：2015 REACH
- CBNumber
- CB8181415
- Molecular Formula
- C7H6F3NO
- Formula Weight
- 177.12
- MOL File
- 121643-44-5.mol
2-Methoxy-3-(trifluoromethyl)pyridine Property
- Boiling point:
- 44 °C
- Density
- 1.297 g/mL at 25 °C
- refractive index
- n20/D 1.441
- Flash point:
- 118 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- clear liquid
- pka
- 0.97±0.10(Predicted)
- color
- Colorless to Almost colorless
- InChI
- InChI=1S/C7H6F3NO/c1-12-6-5(7(8,9)10)3-2-4-11-6/h2-4H,1H3
- InChIKey
- SSAZZVQVJJXPMB-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=CC=C1C(F)(F)F
- CAS DataBase Reference
- 121643-44-5(CAS DataBase Reference)
Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 10-25-36/37/38-20/21/22
- Safety Statements
- 16-26-45-36
- RIDADR
- UN 1992 3/PG 3
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 658359
- Product name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Purity
- 96%
- Packaging
- 5g
- Price
- $86.1
- Updated
- 2023/06/20
- Product number
- M2191
- Product name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $34
- Updated
- 2024/03/01
- Product number
- M2191
- Product name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $114
- Updated
- 2025/07/31
- Product number
- M271975
- Product name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 006761
- Product name
- 2-Methoxy-3-(trifluoromethyl)pyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
2-Methoxy-3-(trifluoromethyl)pyridine Chemical Properties,Usage,Production
storage
2-Methoxy-3-(trifluoromethyl)pyridine store at room temperature.
Uses
2-Methoxy-3-(trifluoromethyl)pyridine belongs to pyridine derivatives and can be used as pharmaceutical intermediates.
Synthesis
124-41-4
65753-47-1
121643-44-5
2-Chloro-3-trifluoromethylpyridine (3 g, 16.53 mmol) was dissolved in 30 mL of a methanol solution of sodium methanolate (5.4 M). The reaction mixture was stirred at room temperature for 48 hours. After completion of the reaction, the mixture was cooled in an ice bath and extracted three times with dichloromethane (DCM). The organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to afford 2-methoxy-3-trifluoromethylpyridine as a colorless liquid (2.7 g, 89% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6, 298 K): δ 3.98 (s, 3H), 7.2 (dd, 1H), 8.11 (d, 1H), 8.45 (d, 1H). Mass Spectrometry (MS): m/z 178.1 [M+1]+, retention time (Rt) = 1.29 min.
References
[1] Patent: WO2013/57711, 2013, A1. Location in patent: Page/Page column 45-46
[2] Patent: WO2013/88404, 2013, A1. Location in patent: Page/Page column 92
[3] Patent: US2015/342951, 2015, A1. Location in patent: Paragraph 0841-0842
2-Methoxy-3-(trifluoromethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methoxy-3-(trifluoromethyl)pyridine manufacturers
- Product
- 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-28
- Product
- 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2025-06-13
- Product
- 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-10