DIGITOXIGENIN

Product Name: DIGITOXIGENIN
CAS No.: 143-62-4
Chemical Name: DIGITOXIGENIN
Synonyms: echujetin;evonogenin;NSC 407806;cerberigenin;THEVETIGENIN;igitoxigenin;DIGITOXYGENIN;DIGITOXIGENIN;digitoxigenine;Digitoxigenin >
CBNumber: CB8187462
Molecular Formula: C23H34O4
Formula Weight: 374.51
MOL File: 143-62-4.mol

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DIGITOXIGENIN Property

Melting point:: 253-255 °C (dec.)(lit.)
alpha: D17 +19.1° (c = 1.36 in methanol)
Boiling point:: 423.5°C (rough estimate)
Density: 1.0284 (rough estimate)
refractive index: 1.4433 (estimate)
storage temp.: Store at -20°C
solubility: DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
pka: 14.93±0.70(Predicted)
form: powder to crystal
color: White to Almost white
optical activity: +2323 (c 0.5, CHCl3)
Water Solubility: 11.24mg/L(30 ºC)
Merck: 14,3162
BRN: 95448
Stability:: Hygroscopic
LogP: 2.640
CAS DataBase Reference: 143-62-4(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 3462 6.1/PG 2
WGK Germany: 3
RTECS: FH4975000
HS Code: 2938.90.0000
HazardClass: 6.1(a)
PackingGroup: II
Toxicity: cat,LDLo,intravenous,254ug/kg (0.254mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITING,Journal of the American Pharmaceutical Association. Vol. 27, Pg. 189, 1938.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D9404
Product name: Digitoxigenin
Purity: non-ionic
Packaging: 10mg
Price: $101
Updated: 2024/03/01

Sigma-Aldrich

Product number: D9404
Product name: Digitoxigenin
Purity: non-ionic
Packaging: 100mg
Price: $618
Updated: 2024/03/01

TCI Chemical

Product number: D0541
Product name: Digitoxigenin
Purity: >97.0%(HPLC)
Packaging: 10mg
Price: $219
Updated: 2024/03/01

Cayman Chemical

Product number: 18229
Product name: Digitoxigenin
Purity: ≥98%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18229
Product name: Digitoxigenin
Purity: ≥98%
Packaging: 10mg
Price: $78
Updated: 2024/03/01

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DIGITOXIGENIN Chemical Properties,Usage,Production

Uses

Cardiotonic;Na+ K+ ATPase inhibitor

Definition

ChEBI: Digitoxigenin is a 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22). It is a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.

Purification Methods

Dissolve digitoxigenin in EtOAc, wash it with H2O, dry it (Na2SO4), evaporate and recrystallise it from 40% aqueous EtOH or aqueous MeOH then EtOAc/Et2O. The UV has max at 218nm ( 14,500 M-1cm-1). The 3-acetate crystallises from Me2CO/Et2O with m 222-227o, [] D 20 +21o (c 1, CHCl3). [Wyss et al. Helv Chim Acta 43 644 1960, Cruz et al. J Org Chem 4 2 3580 1977, Beilstein 18 IV 1468.]

DIGITOXIGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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DIGITOXIGENIN Suppliers

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View Lastest Price from DIGITOXIGENIN manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: DIGITOXIGENIN 143-62-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-23

143-62-4, DIGITOXIGENINRelated Search:

cerberin GITOXIGENIN LANATOSIDE C digitoxigenin+2digitoxose+acetyl-digilanidobos DIGOXIGENIN DIGITALIN GITOXIN DIGOXIN PERUVOSIDE Metildigoxin ACETYLDIGITOXIN digitoxigenin+thevetos LANATOSIDE B Digitoxin Deslanoside DIGITOXIGENIN digoxigenin-mono(digitoxoside) BETA-ACETYLDIGOXIN

5BETA,20[22]-CARDENOLIDE-3BETA,14-DIOL

3BETA,14-DIHYDROXY-5BETA,20[22]-CARDENOLIDE

20(22),5BETA-CARDENOLID-3BETA,14BETA-DIOL

3,14,21-TRIHYDROXY-20(22)-NORCHOLENIC ACID LACTONE

cerberigenin

delta-sup(20:22)-3,14,21-trihydroxynorcholenicacidlactone

digitoxigenine

echujetin

evonogenin

3-beta,14-dihydroxy-5-beta,14-beta-card-20(22)-enolide

3β,14-dihydroxy-5β,20(22)-cardenolide

DIGITOXYGENIN

3β,14-Dihydroxy-5β,20(22)-cardenolide, 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone, 5β,20(22)-Cardenolide-3β,14-diol, Digitoxigenin

3β,14-Dihydroxy-5β,20(22)-cardenolide, 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone, 5β,20(22)-Cardenolide-3β,14-diol

THEVETIGENIN

3,14-dihydroxy-,(3-beta,5-beta)-card-20(22)-enolid

3-beta,14-dihydroxy-5-beta-card-20(22)-enolid

3-beta,14-dihydroxy-5-beta-card-20(22)-enolide

3-beta,14-dioxy-carden-(20:22)-olid

3-beta,14-dioxy-digen-(20:22)-olid

cardogenen-(20:22)-diol-(3-beta,14)

3β,14-Dihydroxy-5β,14β-card-20(22)-enolide

3β,14-Dihydroxy-5β-cardanolide-20(22)-ene

δ20:22-3,14,21-Trihydroxynorcholenic acid lactone

5β,20(22)-Cardenolide-3β

3b,14-Dihydroxy-5b-card-20(22)-enolide

delta20:22-3,14,21-Trihydroxynorcholenic acid lactone

NSC 407806

DIGITOXIGENIN

Digitoxigenin &gt

igitoxigenin

(+)-digitoxigenin

Card-20(22)-enolide, 3,14-dihydroxy-, (3β,5β)-

143-62-4

Asymmetric Synthesis

Chiral Building Blocks

BioChemical

Steroids

Steroids (Others)

Non-Ionic

Complex Molecules

Detergents

Biochemistry

Steroids

Steroids (Others)

ATPase