Difluoxacin hydrochloride
Brand Name(s) in US- Product Name
- Difluoxacin hydrochloride
- CAS No.
- 91296-86-5
- Chemical Name
- Difluoxacin hydrochloride
- Synonyms
- VETRANAL;Difluoxacin;DIFLOXACIN HCL;Difluoxacin HCL;DIFLOXACIN HYDROCHLORIDE;Difloxacin HCl - Bio-X ?;DIFLUOXACIN HYDROCHLORIDE;DifloxacinHydrochlorideSal;-7-(4-methylpiperazin-1-yl);6-Fluoro-1-(4-fluorophenyl)
- CBNumber
- CB8208196
- Molecular Formula
- C21H20ClF2N3O3
- Formula Weight
- 435.85
- MOL File
- 91296-86-5.mol
Difluoxacin hydrochloride Property
- Melting point:
- >245°C (dec.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in aqueous buffer
- form
- powder
- color
- White to off-white
- InChI
- InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H
- InChIKey
- JFMGBGLSDVIOHL-UHFFFAOYSA-N
- SMILES
- C12C=C(C(F)=CC=1C(C(C(=O)O)=CN2C1=CC=C(F)C=C1)=O)N1CCN(C)CC1.Cl
- CAS DataBase Reference
- 91296-86-5(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- RTECS
- VB2008975
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Y0001423
- Product name
- Difloxacin hydrochloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 60 mg
- Price
- $156
- Updated
- 2025/07/31
- Product number
- 33984
- Product name
- Difloxacin hydrochloride
- Purity
- VETRANAL?, analytical standard
- Packaging
- 100mg
- Price
- $72.5
- Updated
- 2025/07/31
- Product number
- 29000
- Product name
- Difloxacin (hydrochloride)
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 29000
- Product name
- Difloxacin (hydrochloride)
- Packaging
- 25mg
- Price
- $275
- Updated
- 2024/03/01
- Product number
- Y0001423
- Product name
- Difloxacin hydrochloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0001423
- Price
- $153
- Updated
- 2024/03/01
Difluoxacin hydrochloride Chemical Properties,Usage,Production
Brand Name(s) in US
Dicural
Description
Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.
Chemical Properties
Off-White to Pale Yellow Solid
Uses
antibacterial, DNA gyrase inhibitor
Uses
A quinolone antibacterial compound. Structurally related to norfloxacin
Uses
A fluoroquinolone antibacterial structurally related to norfloxacin.
References
[1] M B BANSAL H T. Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1987, 31 4: 619-621. DOI: 10.1128/aac.31.4.619
[2] H THADEPALLI S K C S V Gollapudi. Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscess.[J]. Antimicrobial Agents and Chemotherapy, 1986, 30 4: 574-576. DOI: 10.1128/aac.30.4.574
Difluoxacin hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Difluoxacin hydrochloride manufacturers
- Product
- Difluoxacin hydrochloride 91296-86-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2025-05-09
- Product
- Difloxacin Hydrochloride 91296-86-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2024-04-10
- Product
- Difluoxacin hydrochloride 91296-86-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-10