Brand Name(s) in US
ChemicalBook > CAS DataBase List > Difluoxacin hydrochloride

Difluoxacin hydrochloride

Brand Name(s) in US
Product Name
Difluoxacin hydrochloride
CAS No.
91296-86-5
Chemical Name
Difluoxacin hydrochloride
Synonyms
VETRANAL;Difluoxacin;DIFLOXACIN HCL;Difluoxacin HCL;DIFLOXACIN HYDROCHLORIDE;Difloxacin HCl - Bio-X ?;DIFLUOXACIN HYDROCHLORIDE;DifloxacinHydrochlorideSal;-7-(4-methylpiperazin-1-yl);6-Fluoro-1-(4-fluorophenyl)
CBNumber
CB8208196
Molecular Formula
C21H20ClF2N3O3
Formula Weight
435.85
MOL File
91296-86-5.mol
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Difluoxacin hydrochloride Property

Melting point:
>245°C (dec.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in aqueous buffer
form 
powder
color 
White to off-white
InChI
InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H
InChIKey
JFMGBGLSDVIOHL-UHFFFAOYSA-N
SMILES
C12C=C(C(F)=CC=1C(C(C(=O)O)=CN2C1=CC=C(F)C=C1)=O)N1CCN(C)CC1.Cl
CAS DataBase Reference
91296-86-5(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
VB2008975
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001423
Product name
Difloxacin hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
60 mg
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
33984
Product name
Difloxacin hydrochloride
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$72.5
Updated
2025/07/31
Cayman Chemical
Product number
29000
Product name
Difloxacin (hydrochloride)
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
29000
Product name
Difloxacin (hydrochloride)
Packaging
25mg
Price
$275
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001423
Product name
Difloxacin hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001423
Price
$153
Updated
2024/03/01
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Difluoxacin hydrochloride Chemical Properties,Usage,Production

Brand Name(s) in US

Dicural

Description

Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

antibacterial, DNA gyrase inhibitor

Uses

A quinolone antibacterial compound. Structurally related to norfloxacin

Uses

A fluoroquinolone antibacterial structurally related to norfloxacin.

References

[1] M B BANSAL  H T. Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1987, 31 4: 619-621. DOI: 10.1128/aac.31.4.619
[2] H THADEPALLI  S K C  S V Gollapudi. Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscess.[J]. Antimicrobial Agents and Chemotherapy, 1986, 30 4: 574-576. DOI: 10.1128/aac.30.4.574

Difluoxacin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Difluoxacin hydrochloride manufacturers

Shaanxi Xianhe Biotech Co., Ltd
Product
Difluoxacin hydrochloride 91296-86-5
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-05-09
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Difloxacin Hydrochloride 91296-86-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-10
Hebei Chuanghai Biotechnology Co., Ltd
Product
Difluoxacin hydrochloride 91296-86-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-10

91296-86-5, Difluoxacin hydrochlorideRelated Search:


  • VETRANAL
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