Description Mechanism of action
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Difloxacin

Description Mechanism of action
Product Name
Difloxacin
CAS No.
98106-17-3
Chemical Name
Difloxacin
Synonyms
a56619;DIFLOXACIN;Difloxacin USP/EP/BP;-1-piperazinyl)-4-oxo-;DIFLOXACINHCL/MESYLATE;Acrylamide Impurity 32;Difloxacin Hydrochloride Salt;3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl;6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci;6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
CBNumber
CB5175282
Molecular Formula
C21H19F2N3O3
Formula Weight
399.39
MOL File
98106-17-3.mol
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Difloxacin Property

Melting point:
279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
Boiling point:
595.5±50.0 °C(Predicted)
Density 
1.409±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
pka
6.17±0.41(Predicted)
color 
White to Pale Yellow
CAS DataBase Reference
98106-17-3(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H331Toxic if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
272206
Product name
Difloxacin hydrochloride salt
Packaging
50mg
Price
$405
Updated
2021/12/16
AK Scientific
Product number
V2078
Product name
Difloxacin
Packaging
250mg
Price
$407
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593389
Product name
Difloxacin
Packaging
50μg
Price
$425
Updated
2021/12/16
Matrix Scientific
Product number
098810
Product name
6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Purity
95+%
Packaging
1g
Price
$588
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002350
Product name
DIFLOXACIN
Purity
95.00%
Packaging
1G
Price
$630
Updated
2021/12/16
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Difloxacin Chemical Properties,Usage,Production

Description

Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin.

Mechanism of action

Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. 

Physical properties

Whtie-Cream to Yellowish Crystalline Powder

Uses

Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin.

Definition

ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall as the monohydrochloride salt) for the treatment of bacterial infections in dogs.

Difloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Difloxacin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 15920483169
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17944
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9590
Advantage
58
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4515
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
021-61984905-1 18016477331
Email
synchempharma@aliyun.com
Country
China
ProdList
6451
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
132020
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15495
Advantage
58
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4398
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55477
Advantage
58
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View Lastest Price from Difloxacin manufacturers

Dideu Industries Group Limited
Product
Difloxacin 98106-17-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-19
Shaanxi Dideu Medichem Co. Ltd
Product
Difloxacin 98106-17-3
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-05-12

98106-17-3, DifloxacinRelated Search:


  • DIFLOXACIN
  • -1-piperazinyl)-4-oxo-
  • 3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl
  • a56619
  • 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt
  • Difloxacin Hydrochloride Salt
  • 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
  • DIFLOXACINHCL/MESYLATE
  • 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic
  • 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
  • 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid
  • 6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic ac
  • 6-Fluoro-1-(4-fluorophenyl)-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
  • 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicaci
  • Difloxacin USP/EP/BP
  • Acrylamide Impurity 32
  • 98106-17-3
  • C21H20ClF2N3O3
  • C21H19F2N3O3
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral Reagents