5-INDANOL

Uses

Product Name: 5-INDANOL
CAS No.: 1470-94-6
Chemical Name: 5-INDANOL
Synonyms: 1H-Inden-5-ol, 2,3-dihydro-;2,3-Dihydro-1H-inden-5-ol;INDAN-5-OL;5-HYDROXYINDAN;5-HYDROXYINDANE;Indanol-5;5-INDANOL;5-INDANOL 99%;5-Indanol,99%;Indan-5-ol 98%
CBNumber: CB8210012
Molecular Formula: C9H10O
Formula Weight: 134.18
MOL File: 1470-94-6.mol

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5-INDANOL Property

Melting point:: 51-53 °C (lit.)
Boiling point:: 255 °C (lit.)
Density: 0.8540 (rough estimate)
refractive index: 1.5630 (estimate)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: 6.3g/l
form: powder to crystal
pka: 10.37±0.20(Predicted)
color: slightly brown
BRN: 1936314
CAS DataBase Reference: 1470-94-6(CAS DataBase Reference)
EPA Substance Registry System: 5-Indanol (1470-94-6)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 21-20/21/22
Safety Statements: 36/37-36
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NK7525000
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29062900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H311Toxic in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I2215
Product name: 5-Indanol
Purity: 99%
Packaging: 25g
Price: $58
Updated: 2024/03/01

TCI Chemical

Product number: H0251
Product name: 5-Hydroxyindan
Purity: >99.0%(GC)
Packaging: 25g
Price: $87
Updated: 2024/03/01

TCI Chemical

Product number: H0251
Product name: 5-Hydroxyindan
Purity: >99.0%(GC)
Packaging: 100g
Price: $264
Updated: 2024/03/01

TRC

Product number: I499850
Product name: 5-Indanol
Packaging: 25g
Price: $250
Updated: 2021/12/16

AK Scientific

Product number: X3320
Product name: 5-Indanol
Packaging: 5g
Price: $39
Updated: 2021/12/16

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5-INDANOL Chemical Properties,Usage,Production

Uses

5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin; a compound which has been shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic.

Description

5-Indanol, mp 54–55 ℃, bp 255 ℃, is produced from indan [496-11-7] by a sulfonation–alkali-fusion process. A synthesis for 1,1,3,3-tetraalkylindanols was developed by Bayer, which involves the reaction of isoolefins with secondary alkenylphenols (or compounds generating them under the reaction conditions) at 100–250 ℃ and in the presence of acidic catalysts. An example is the reaction of isobutene with bisphenol A in the presence of acid-activated clays which yields 1,1,3,3-tetramethyl-5-indanol [53718-26-6], mp 115 ℃, bp (2.66 kPa) 156 ℃, in a yield of 80% of the theoretical, and 4-tert-butylphenol as a coproduct.

Chemical Properties

light brown to grey-brown crystalline powder or

Uses

5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin (S635000); a compound which has been shown to reduce blood pressure in mammals and also has been used as a b-lactam antibiotic.

Definition

ChEBI: A member of the class of phenols that is indan which has been hydroxylated at position 5.

Purification Methods

Crystallise 5-hydroxyindane from pet ether (m 56o) or pentane (m 59-60o). It has UV with max at 283.5nm (cyclohexane). The 3,5-dinitrobenzoyl derivative has m 156o. [Beilstein 6 III 2428, 6 IV 3829.]

5-INDANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-INDANOL Suppliers

Americas 1 Belgium 1 China 86 Europe 1 Germany 7 Hungary 1 India 5 Japan 2 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 11 United States 26 Global 145

Alchem Pharmtech,Inc.

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View Lastest Price from 5-INDANOL manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5-INDANOL 1470-94-6
Price: US $50.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-22

Career Henan Chemical Co

Product: 5-Indanol 1470-94-6
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

1470-94-6, 5-INDANOLRelated Search:

4,6-bis(isopropyl)-1,1,3,3-tetramethylindan-5-ol 6-Hydroxy-1-indanone Hematoxylin 5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDANE 4,5-DIMETHOXY-1-INDANONE 5-METHOXY-1-INDANONE-3-ACETIC ACID 5-METHOXYINDAN 6-Methoxy-1H-indanone R(+)-IAA-94 HEMATOXYLIN 5-Methoxy-1-indanone 5-INDANOL 5,6-Dimethoxy-1-indanone BRAZILIN 3,3,3',3'-TETRAMETHYL-5,5',6,6'-TETRAPROPOXY-1,1'-SPIROBIINDANE (1S,2S)-1-Amino-2-indanol 2-INDANOL 99%,2-INDANOL 1-METHOXY-2-INDANOL,1-METHOXY-2-INDANOL 98+%

2,3-dihydro-1h-inden-5-o

Indanol-5

INDAN-5-OL

5-INDANOL

5-HYDROXYHYDRINDENE

5-HYDROXYINDAN

1H-Inden-5-ol, 2,3-dihydro-

Indan-5-ol 98%

2,3-Dihydro-1H-inden-5-ol

5-HYDROXYINDANE

5-INDANOLE 99+%

5-INDANOL 99%

5-Oxyhydrindene

5-Indanol,99%

Cis-1-amino-2,3-dihydro-1H-inden-2-ol

Indan-5-ol, 2,3-Dihydro-1H-inden-5-ol

5-Hydroxyhydrindene 5-Indanol

5-Indanole for synthesis

5-Hydroxyindan&gt

1470-94-6

Phenols

Oxygen Compounds

Organic Building Blocks

Building Blocks

Indane/Indanone and Derivatives