Ethyl (R)-3-hydroxybutyrate

Product Name: Ethyl (R)-3-hydroxybutyrate
CAS No.: 24915-95-5
Chemical Name: Ethyl (R)-3-hydroxybutyrate
Synonyms: grape butyrate;(R)-grape butyrate;2-ethyl-3-hydroxybutanoate;ETHYL (R)-3-HYDROXYBUTYRATE;ETHYL (R)-3-HYDROXYBUTYLATE;ethyl (3R)-3-hydroxybutanoate;ETHYL R-(-)-3-HYDROXYBUTANOATE;(R)-(-)-Ethyl 3-Hydrobutyrate;Ethyl (R)-3-hydroxybutyrate,98%;ETHYL (R)-(-)-3-HYDROXYBUTYRATE
CBNumber: CB8214494
Molecular Formula: C6H12O3
Formula Weight: 132.16
MOL File: 24915-95-5.mol

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Ethyl (R)-3-hydroxybutyrate Property

alpha: -45.5 º (589nm, c=1, CHCl3)
Boiling point:: 75-76 °C/12 mmHg (lit.)
Density: 1.017 g/mL at 25 °C (lit.)
vapor pressure: 17.2Pa at 20℃
refractive index: n20/D 1.42(lit.)
Flash point:: 148 °F
storage temp.: 2-8°C
pka: 14.45±0.20(Predicted)
form: Liquid
color: Clear, Colorless
Specific Gravity: 1.017
optical activity: [α]20/D 46°, c = 1 in chloroform
Water Solubility: soluble
LogP: 0.341 at 20℃
CAS DataBase Reference: 24915-95-5(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38-52
Safety Statements: 24/25
RIDADR: 1993
WGK Germany: 3
HS Code: 29181990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 347329
Product name: Ethyl (R)-(?)-3-hydroxybutyrate
Purity: 98%
Packaging: 1g
Price: $10.64
Updated: 2024/03/01

Sigma-Aldrich

Product number: 347329
Product name: Ethyl (R)-(?)-3-hydroxybutyrate
Purity: 98%
Packaging: 5g
Price: $51.48
Updated: 2024/03/01

TCI Chemical

Product number: H1029
Product name: Ethyl (R)-(-)-3-Hydroxybutyrate
Purity: >98.0%(GC)
Packaging: 1g
Price: $64
Updated: 2024/03/01

TCI Chemical

Product number: H1029
Product name: Ethyl (R)-(-)-3-Hydroxybutyrate
Purity: >98.0%(GC)
Packaging: 5g
Price: $132
Updated: 2024/03/01

Alfa Aesar

Product number: J63400
Product name: Ethyl (R)-(-)-3-hydroxybutyrate
Packaging: 1g
Price: $38.9
Updated: 2021/12/16

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Ethyl (R)-3-hydroxybutyrate Chemical Properties,Usage,Production

Description

Ethyl (R)-(-)-3-Hydroxybutyrate is a chiral starting material for the production of numerous biologically active compounds.

Chemical Properties

clear colorless liquid

Uses

Ethyl (R)-(-)-3-hydroxybutyrate is a chiral building block for the preparation of bioactive compounds used in the pharmaceutical industry. It is formed during the hydrolysis of poly-3-hydroxybutyrate.

Definition

ChEBI: Ethyl (R)-3-hydroxybutanoate is an ethyl 3-hydroxybutyrate. It is functionally related to a (R)-3-hydroxybutyric acid.

General Description

Ethyl (R)-3-hydroxybutyrate is an enantiomer of 3-hydroxybutyric acid. It is synthesized from diethyl succinate in a one-pot, stereoselective, high-yield process by using asymmetric synthesis and hydrogenation. The reaction vessel used for this synthesis is a reaction solution that has been optimized to be resistant to high pressure and temperature. This product can be used as a renewable feedstock in the production of polyesters and other polymers.

Synthesis

(R)-β-Butryrolactone (20 g, 230 mmol) was dissolved in 500 mLethanol with 1.0 mL H2SO4 and stirred at room temperature. Aliquots(100 μL) were added to 1.0 mL of methanol and analyzed by GC-MS for conversion of the lactone. Upon completion (> 48 h), a small amount of solid sodium bicarbonate was added and the solvent removed by rotary evaporation. The residue was taken up in dichloromethane and washed with water. The water layer was extracted twice with ethyl acetate. The pooled organic layers were dried with magnesium sulfate, which was then filtered and the solvent removed by rotary evaporation to yield Ethyl (R)-3-hydroxybutyrate as a clear oil (20.2 g, 66%).

Ethyl (R)-3-hydroxybutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl (R)-3-hydroxybutyrate Suppliers

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View Lastest Price from Ethyl (R)-3-hydroxybutyrate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Ethyl (R)-3-Hydroxybutyrate 24915-95-5
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-15

Hebei Mojin Biotechnology Co., Ltd

Product: Ethyl (R)-3-hydroxybutyrate 24915-95-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-09-26

ChiRial Biomaterial Co Ltd

Product: Ethyl (R)-3-Hydroxybutyrate 24915-95-5
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 97%
Supply Ability: 10 tons
Release date: 2023-03-23

24915-95-5, Ethyl (R)-3-hydroxybutyrateRelated Search:

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(R)-(-)-ETHYL 3-HYDROXYBUTANOATE

(R)-(-)-ETHYL 3-HYDROXYBUTYRATE

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ENZYME MEMBRANE REACTOR (WITHOUT SUPPLEMENTARY ACCESSORIES) EE 99+%

ETHYL R-(-)-3-HYDROXYBUTANOATE

ETHYL (R)-(-)-3-HYDROXYBUTYRATE

ETHYL (R)-3-HYDROXYBUTYRATE

ETHYL (R)-3-HYDROXYBUTANOATE R-3-HYDROXYBUTYRIC ACID ETHYL ESTER

Ethyl (R)-3-hydroxybutyrate,98%

(R)-(-)-Ethyl 3-Hydrobutyrate

ETHYL (R)-3-HYDROXYBUTYLATE

Ethyl (R)-3-hydroxybutyrate, 98% 5GR

grape butyrate

ethyl (3R)-3-hydroxybutanoate

Butanoic acid,3-hydroxy-, ethyl ester, (3R)-

Ethyl (R)-(-)-3-hydroxybutyrate 98%

2-ethyl-3-hydroxybutanoate

Ethyl(R)-(-)-3-Hydroxybutyrate&gt

Ethyl (R)-3-hydroxybutyrate Basic information

(R)-grape butyrate

24915-95-5

24915-95-9

C6H12O3

CH3CHOHCH2CO2C2H5

Asymmetric Synthesis

Simple Alcohols (Chiral)

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Organic Building Blocks

Chiral Alcohols

Alcohols, Hydroxy Esters and Derivatives

Chiral Compounds

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Simple Alcohols (Chiral)

Synthetic Organic Chemistry

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