1H-Benzimidazole-2-carboxaldehyde
- Product Name
- 1H-Benzimidazole-2-carboxaldehyde
- CAS No.
- 3314-30-5
- Chemical Name
- 1H-Benzimidazole-2-carboxaldehyde
- Synonyms
- AKOS NCG1-0071;CHEMBRDG-BB 430030;CHEMBRDG-BB 4300303;2-Formylbenzimidazole;2-Formyl-1H-benzimidazole;Benzimidazole-2-carbaldehyde;Benzimidazole-2-formaldehyde;2-Benzimidazolecarboxaldehyde;1H-BENZIMIDAZOLE-2-CARBALDEHYDE;1H-BENZOIMIDAZOLE-2-CARBALDEHYDE
- CBNumber
- CB8243683
- Molecular Formula
- C8H6N2O
- Formula Weight
- 146.15
- MOL File
- 3314-30-5.mol
1H-Benzimidazole-2-carboxaldehyde Property
- Melting point:
- 224°C
- Boiling point:
- 361.8±25.0 °C(Predicted)
- Density
- 1.368±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 10.61±0.10(Predicted)
- color
- Light yellow to yellow
- InChI
- InChI=1S/C8H6N2O/c11-5-8-9-6-3-1-2-4-7(6)10-8/h1-5H,(H,9,10)
- InChIKey
- DQOSJWYZDQIMGM-UHFFFAOYSA-N
- SMILES
- C1(C=O)NC2=CC=CC=C2N=1
- CAS DataBase Reference
- 3314-30-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H999828
- Product name
- 1H-Benzo[d]imidazole-2-carbaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR1856
- Product name
- 1H-Benzimidazole-2-carboxaldehyde
- Purity
- 95%
- Packaging
- 250mg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 4H15-1-X1
- Product name
- 1H-Benzimidazole-2-carboxaldehyde
- Packaging
- 250mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- OR1856
- Product name
- 1H-Benzimidazole-2-carboxaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
- Product number
- 4H15-1-X1
- Product name
- 1H-Benzimidazole-2-carboxaldehyde
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
1H-Benzimidazole-2-carboxaldehyde Chemical Properties,Usage,Production
Definition
ChEBI: 1H-benzimidazole-2-carbaldehyde is a benzimidazolecarbaldehyde.
Synthesis
5466-57-9
3314-30-5
General procedure for the synthesis of 1H-benzimidazole-2-carbaldehyde from 2-(dichloromethyl)-1H-benzo[d]imidazole: 15 mL (276 mmol, 6.6 eq.) of concentrated sulfuric acid was slowly added dropwise to a reaction vial containing 8.40 g (41.8 mmol) of 2-(dichloromethyl)-1H-benzo[d]imidazole (Compound L5), and the formation of yellow bubbles was observed. After completion of dropwise addition, stirring was continued for 10 min to ensure complete dissolution of compound L5. Subsequently, the reaction mixture was heated in an oil bath at 80 °C for 1 h. The heating was stopped after completion of the reaction. After the reaction mixture was cooled to room temperature, 150 mL of ice water was added and the pH was adjusted with 4 N NaOH aqueous solution to 7. At this point, a yellow solid precipitated from the solution. The solid product was collected by filtration and dried to give 5.21 g of 1H-benzimidazole-2-carbaldehyde (compound L6) in 85.3% yield.
References
[1] Patent: CN104211632, 2016, B. Location in patent: Paragraph 0131; 0132
[2] Pharmazie, 1980, vol. 35, # 10, p. 585 - 586
1H-Benzimidazole-2-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Benzimidazole-2-carboxaldehyde Suppliers
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- interchim@interchim.com
- Country
- France
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View Lastest Price from 1H-Benzimidazole-2-carboxaldehyde manufacturers
- Product
- 1H-Benzimidazole-2-carboxaldehyde 3314-30-5
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-07