Description References
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Esculin

Description References
Product Name
Esculin
CAS No.
531-75-9
Chemical Name
Esculin
Synonyms
ESCULIN;Escosyl;BICOLOIN;AESCULIN;POLYDROM;Esculine;Bicolorin;Crataegin;Polychrom;vitaminc2
CBNumber
CB8245061
Molecular Formula
C15H16O9
Formula Weight
340.28
MOL File
531-75-9.mol
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Esculin Property

Melting point:
203 °C
alpha 
-88 º (c=2,dioxane/water1:1)
Boiling point:
396.1°C (rough estimate)
Density 
0.791 g/mL at 20 °C
refractive index 
-79 ° (C=2.4, 50% Dioxane)
Flash point:
15 °C
storage temp. 
2-8°C
solubility 
methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
pka
7.00±0.20(Predicted)
form 
Liquid
color 
Clear
optical activity
[α]20/D 41±2°, c = 5% in pyridine
Water Solubility 
MODERATELY SOLUBLE
Merck 
3698
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
YRABYCJKUBFWQY-FHXAZYNBSA-N
CAS DataBase Reference
531-75-9(CAS DataBase Reference)
NIST Chemistry Reference
7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
EPA Substance Registry System
Esculin (531-75-9)
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Safety

Hazard Codes 
F,C,Xi
Risk Statements 
11-20/21/22-34-68/20/21/22-36/37/38
Safety Statements 
26-36/37/39-45-24/25-36/37-16
RIDADR 
UN 2924 3/PG 2
WGK Germany 
3
RTECS 
DJ3085000
3-10-23
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E8250
Product name
Esculin hydrate
Purity
≥98%
Packaging
5g
Price
$42.8
Updated
2018/11/20
Sigma-Aldrich
Product number
1.00842
Product name
Esculin
Purity
for microbiology
Packaging
25 g
Price
$112
Updated
2021/03/22
Sigma-Aldrich
Product number
Y0001612
Product name
Esculin
Purity
European Pharmacopoeia (EP) Reference Standard
Price
$190
Updated
2021/03/22
Sigma-Aldrich
Product number
06212
Product name
Esculin hydrate
Purity
analytical standard
Packaging
100mg
Price
$202
Updated
2020/08/18
Sigma-Aldrich
Product number
E8250
Product name
Esculin hydrate
Purity
≥98%
Packaging
100g
Price
$418
Updated
2018/11/20
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Esculin Chemical Properties,Usage,Production

Description

Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.

References

[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011

Chemical Properties

White to nearly white

Uses

esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.

Uses

esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.

Definition

ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.

Esculin Preparation Products And Raw materials

Raw materials

Preparation Products

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Esculin Suppliers

Lingyuan Bebiansen Biological Technology Co., Ltd
Tel
Email
2837458851@qq.com
Country
China
ProdList
10002
Advantage
58
Nanjing Bencao Yikang Biotechnology Co., Ltd
Tel
025-69790911-
Email
522593521@qq.com
Country
China
ProdList
946
Advantage
58
Shanxi Yuning Biotechnology Co., Ltd.
Email
1639455302@qq.com
Country
China
ProdList
284
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2213
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
Chembest Research Laboratories Limited
Tel
021-20908456-
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
5948
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
43503
Advantage
61
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View Lastest Price from Esculin manufacturers

Wuhan wingroup Pharmaceutical Co., Ltd
Product
Esculin 531-75-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-07-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
Esculin 531-75-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Esculin 531-75-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

531-75-9, EsculinRelated Search:


  • BICOLOIN
  • ESCULETIN-6-O-GLUCOSIDE
  • ESCULIN
  • ESCULETIN-6-GLUCOSIDE
  • ESCULOSIDE
  • Esculinsesquimonohydrate
  • 2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-
  • 6,7-DIHYDROXYCOUMARIN-6-O-GLUCOSIDE
  • 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-one
  • 6-(BETA-D-GLUCOPYRANOSYLOXY)-7-HYDROXY-2H-1-BEZOPYRAN-2-ONE
  • 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
  • 6,7-Dihydrocoumarin-6-glucoside
  • 6-β-Glucosido-7-hydrox
  • Aesculin;Bicolorin;6,7-Dihydrocoumarin-6-glucoside;6,7-Dihydroxycoumarin 6-glucoside;Enallachrome;Escosyl;Esculetin-6-β-D-glucopyranoside;Esculin;Esculinic acid;Esculoside;6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one;6-β-Glucosido-7-hydrox
  • Esculinic acid
  • ESCULIN, PLANT EXTRACT 10:1
  • AESCULIN (Esculin Sesquihydrate)
  • EsculinNLT98%
  • 7-hydroxycoumarin-6-yl beta-d-glucopyranoside
  • ESCULIN(ESCULETIN-6-GLUCOSIDE)(P)
  • 7-HYDROXY-6-O-GLUCOSYLCOUMARIN
  • 6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin
  • ESCULIN extrapure
  • 7-hydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one hydrate
  • AESCULETIN
  • AESCULETIN-6B-D-GLUCOPYRANOSIDE
  • AESCULETIN-6-BETA-D-GLUCOPYRANOSIDE
  • AESCULIN
  • POLYDROM
  • POLYCHROME
  • 6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-on
  • Bicolorin
  • Crataegin
  • Enallachrome
  • Escosyl
  • Esculetin 6-beta-D-glucoside
  • Esculine
  • Polychrom
  • Vitamin C2
  • vitaminc2
  • 6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE
  • Esculin,Esculine
  • 6-(b-D-Glucopyranosyloxy)-7-hydroxycoumarin
  • Esculetin 6-b-D-glucoside
  • Esculin hydrate,97%
  • 6-glucoside hydrate
  • F. bangeana DC.p.e
  • 6-glucoside hydrat
  • 7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one
  • Esculin hydrate, 97% 10GR
  • Aesculin (Esculin)
  • Schillerstoff
  • 2H-1-Benzopyran-2-one,6-(b-D-glucopyranosyloxy)-7-hydroxy-
  • 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
  • 6,7-dihydroxychromen-2-one 6-β-D-glucoside
  • 6,7-dihydroxycoumarin 6-β-D-glucoside
  • 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy- 6-(hydroxymethyl)-2-tetrahydropyranyl]oxy}-2-chromenone
  • Esculetin 6-β-D-glucoside