Esculin

Description References

Product Name: Esculin
CAS No.: 531-75-9
Chemical Name: Esculin
Synonyms: ESCULIN;Escosyl;BICOLOIN;AESCULIN;POLYDROM;Esculine;Bicolorin;Crataegin;Polychrom;vitaminc2
CBNumber: CB8245061
Molecular Formula: C15H16O9
Formula Weight: 340.28
MOL File: 531-75-9.mol

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Esculin Property

Melting point:: 203 °C
alpha: -88 º (c=2,dioxane/water1:1)
Boiling point:: 396.1°C (rough estimate)
Density: 0.791 g/mL at 20 °C
vapor pressure: 0Pa at 25℃
refractive index: -79 ° (C=2.4, 50% Dioxane)
Flash point:: 15 °C
storage temp.: 2-8°C
solubility: methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
form: Liquid
pka: 7.00±0.20(Predicted)
color: Clear
optical activity: [α]20/D 41±2°, c = 5% in pyridine
Water Solubility: MODERATELY SOLUBLE
Merck: 3698
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: YRABYCJKUBFWQY-FHXAZYNBSA-N
LogP: -1.307 (est)
CAS DataBase Reference: 531-75-9(CAS DataBase Reference)
NIST Chemistry Reference: 7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
EPA Substance Registry System: Esculin (531-75-9)

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Safety

Hazard Codes: F,C,Xi
Risk Statements: 11-20/21/22-34-68/20/21/22-36/37/38
Safety Statements: 26-36/37/39-45-24/25-36/37-16
RIDADR: UN 2924 3/PG 2
WGK Germany: 3
RTECS: DJ3085000
F: 3-10-23
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E8250
Product name: Esculin hydrate
Purity: ≥98%
Packaging: 5g
Price: $58.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 02350
Product name: Esculin hydrate
Purity: ≥98.0%(HPLC)
Packaging: 10g
Price: $83.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 02350
Product name: Esculin hydrate
Purity: ≥98.0%(HPLC)
Packaging: 50g
Price: $302
Updated: 2024/03/01

Sigma-Aldrich

Product number: 06212
Product name: Esculin hydrate
Purity: analytical standard
Packaging: 100mg
Price: $75.4
Updated: 2022/05/15

Sigma-Aldrich

Product number: Y0001612
Product name: Esculin
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001612
Price: $153
Updated: 2024/03/01

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Esculin Chemical Properties,Usage,Production

Description

Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.

References

[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011

Chemical Properties

White to nearly white

Uses

esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.

Uses

esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.

Uses

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Definition

ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.

General Description

Esculin hydrate has vasoprotective and venotonic properties.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).

Esculin Preparation Products And Raw materials

Raw materials

Preparation Products

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Esculin Suppliers

Belgium 1 Canada 1 China 337 Europe 3 France 1 Germany 3 India 15 Switzerland 2 United Kingdom 12 United States 46 Global 421

Shanghai Zhiyun Biotechnology Co., Ltd

Tel: 13119135307
Email: 3809801531@qq.com
Country: China
ProdList: 2767
Advantage: 58

Xi`an Tian Guangyuan Biotech Co., Ltd.

Tel: 17391926474
Email: 2539013658@qq.com
Country: China
ProdList: 205
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8415
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

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View Lastest Price from Esculin manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Esculin 531-75-9
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 1 ton
Release date: 2024-08-15

R&D Scientific Inc.

Product: Esculin 531-75-9
Price: US $780.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-06-24

Hebei Kingfiner Technology Development Co.Ltd

Product: ESCULIN 531-75-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000%
Release date: 2023-11-27

531-75-9, EsculinRelated Search:

Isofraxidin Tetrahydro-4H-pyran-4-one Centchroman Tetrahydrofuran FRAXIN Furazolidone CHLOROPHOSPHONAZO III Esculin aglucon,Esculin aglycon D-(-)-Salicin Icariin Matrine ERIOCITRIN AESCIN IB(SH) Eribulin Erlotinib hydrochloride Eribulin Mesylate ERIODICTYOL-7-GLUCOSIDE 4-Ethoxyphenol

BICOLOIN

ESCULETIN-6-O-GLUCOSIDE

ESCULIN

ESCULETIN-6-GLUCOSIDE

ESCULOSIDE

Esculinsesquimonohydrate

2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-

6,7-DIHYDROXYCOUMARIN-6-O-GLUCOSIDE

6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-one

6-(BETA-D-GLUCOPYRANOSYLOXY)-7-HYDROXY-2H-1-BEZOPYRAN-2-ONE

6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one

6,7-Dihydrocoumarin-6-glucoside

6-β-Glucosido-7-hydrox

Aesculin;Bicolorin;6,7-Dihydrocoumarin-6-glucoside;6,7-Dihydroxycoumarin 6-glucoside;Enallachrome;Escosyl;Esculetin-6-β-D-glucopyranoside;Esculin;Esculinic acid;Esculoside;6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one;6-β-Glucosido-7-hydrox

Esculinic acid

ESCULIN, PLANT EXTRACT 10:1

AESCULIN (Esculin Sesquihydrate)

EsculinNLT98%

7-hydroxycoumarin-6-yl beta-d-glucopyranoside

ESCULIN(ESCULETIN-6-GLUCOSIDE)(P)

7-HYDROXY-6-O-GLUCOSYLCOUMARIN

6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin

ESCULIN extrapure

7-hydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one hydrate

AESCULETIN

AESCULETIN-6B-D-GLUCOPYRANOSIDE

AESCULETIN-6-BETA-D-GLUCOPYRANOSIDE

AESCULIN

POLYDROM

POLYCHROME

6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-on

Bicolorin

Crataegin

Enallachrome

Escosyl

Esculetin 6-beta-D-glucoside

Esculine

Polychrom

Vitamin C2

vitaminc2

6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE

Esculin，Esculine

6-(b-D-Glucopyranosyloxy)-7-hydroxycoumarin

Esculetin 6-b-D-glucoside

Esculin hydrate,97%

6-glucoside hydrate

F. bangeana DC.p.e

6-glucoside hydrat

7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one

Esculin hydrate, 97% 10GR

Aesculin (Esculin)

Schillerstoff

2H-1-Benzopyran-2-one,6-(b-D-glucopyranosyloxy)-7-hydroxy-

2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-

6,7-dihydroxychromen-2-one 6-β-D-glucoside

6,7-dihydroxycoumarin 6-β-D-glucoside

7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy- 6-(hydroxymethyl)-2-tetrahydropyranyl]oxy}-2-chromenone

Esculetin 6-β-D-glucoside