4-Amino-3-iodobenzotrifluoride

Product Name: 4-Amino-3-iodobenzotrifluoride
CAS No.: 163444-17-5
Chemical Name: 4-Amino-3-iodobenzotrifluoride
Synonyms: 2-IODO-4-(TRIFLUOROMETHYL)ANILINE;4-AMINO-3-IODOBENZOTRIFLUORIDE;3-iodo-4-aminobenzotrifluoride;4-Amino-3-iodobenzotrifluoride,98%;2-Iodo-4-(trifluoromethyl)aniline>2-iodo-4-(trifluoroMethyl)benzenaMine;4-(TRIFLUOROMETHYL)-2-IODOBENZENAMINE;4-amino-3-iodo-trifluoromethylbenzene;BenzenaMine, 2-iodo-4-(trifluoroMethyl)-;2-Iodo-4-(trifluoromethyl)aniline【4-Amino-3-iodobenzotrifluoride】
CBNumber: CB8245975
Molecular Formula: C7H5F3IN
Formula Weight: 287.02
MOL File: 163444-17-5.mol

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4-Amino-3-iodobenzotrifluoride Property

Melting point:: 50 °C
Boiling point:: 252.8±40.0 °C(Predicted)
Density: 1.948±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 0.70±0.10(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C7H5F3IN/c8-7(9,10)4-1-2-6(12)5(11)3-4/h1-3H,12H2
InChIKey: UKKWTZPXYIYONW-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(C(F)(F)F)C=C1I
CAS DataBase Reference: 163444-17-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39-36/37
RIDADR: UN2811
HazardClass: IRRITANT
HS Code: 29214200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0794
Product name: 2-Iodo-4-(trifluoromethyl)aniline
Purity: >98.0%(GC)
Packaging: 5g
Price: $59
Updated: 2025/07/31

TCI Chemical

Product number: I0794
Product name: 2-Iodo-4-(trifluoromethyl)aniline
Purity: >98.0%(GC)
Packaging: 25g
Price: $229
Updated: 2025/07/31

TRC

Product number: I724783
Product name: 2-Iodo-4-(trifluoromethyl)aniline
Packaging: 250mg
Price: $55
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3830-K-43
Product name: 4-Amino-3-iodobenzotrifluoride
Purity: 97%
Packaging: 500g
Price: $500
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0022814
Product name: 4-AMINO-3-IODOBENZOTRIFLUORIDE
Purity: 95.00%
Packaging: 5G
Price: $795.8
Updated: 2021/12/16

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4-Amino-3-iodobenzotrifluoride Chemical Properties,Usage,Production

Chemical Properties

light brown powder

Synthesis

455-14-1

163444-17-5

Step 2: Synthesis of 2-iodo-4-(trifluoromethyl)aniline In a 500 mL three-necked round-bottomed flask, 4-(trifluoromethyl)aniline (22.5 g, 0.14 mol) and methanol (100 mL) were added. The reaction system was cooled to 0 °C, followed by slow dropwise addition of a dichloromethane (100 mL) solution of ICl (25 g, 0.15 mol). After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. The reaction process was monitored by thin layer chromatography (TLC) (unfolding agent: ethyl acetate/petroleum ether = 1:10, Rf = 0.5). Post-treatment: The reaction mixture was concentrated under reduced pressure to remove the solvent. The residue was redissolved in dichloromethane, subsequently washed with water and dried over anhydrous sodium sulfate. Finally, the dried organic phase was concentrated under reduced pressure to give 37.8 g (97% yield) of the target product 2-iodo-4-(trifluoromethyl)aniline. Product characterization: 1H NMR (300 MHz, CDCl3) δ: 7.86 (d, J = 1.2 Hz, 1H), 7.36 (dd, J = 8.4, 1.8 Hz, 1H), 6.73 (d, J = 8.7 Hz, 1H), 4.41 (br, 2H).

References

[1] Heterocycles, 2002, vol. 57, # 3, p. 465 - 476
[2] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 91
[3] Patent: WO2011/112731, 2011, A2. Location in patent: Page/Page column 196
[4] Synthesis, 2004, # 11, p. 1869 - 1873
[5] Synlett, 2014, vol. 25, # 3, p. 399 - 402

4-Amino-3-iodobenzotrifluoride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-3-iodobenzotrifluoride Suppliers

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View Lastest Price from 4-Amino-3-iodobenzotrifluoride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Amino-3-iodobenzotrifluoride 163444-17-5
Price: US $0.00-0.00/KG
Min. Order: 50mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Amino-3-iodobenzotrifluoride 163444-17-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Amino-3-iodobenzotrifluoride 163444-17-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

163444-17-5, 4-Amino-3-iodobenzotrifluorideRelated Search:

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4-Amino-3-iodobenzotrifluoride,98%

2-Iodo-4-(trifluoromethyl)aniline【4-Amino-3-iodobenzotrifluoride】

163444-17-5

C7H5F3IN

Fluorine series

Aromatic Halides (substituted)

API intermediates