7-Hydroxygranisetron

Product Name: 7-Hydroxygranisetron
CAS No.: 4498-67-3
Chemical Name: 7-Hydroxygranisetron
Synonyms: INDAPAMIDE;1H-INDAZOLE-3-CARBOXYLIC ACID;INDAZOLE-3-CARBOXYLIC ACID;1H-INDAZOL-3-CARBONIC ACID;NSC 520610;AKOS BB-9978;3-CARBOXYINDAZOLE;Indazole - 3 - carbo;3-Carboxy-1H-indazole;Indazole-3-carboxylicaci
CBNumber: CB8247050
Molecular Formula: C8H6N2O2
Formula Weight: 162.15
MOL File: 4498-67-3.mol

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7-Hydroxygranisetron Property

Melting point:: 266-270 °C (dec.)
Boiling point:: 443.7±18.0 °C(Predicted)
Density: 1.506±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 3.03±0.10(Predicted)
form: powder
color: beige
BRN: 6354
InChI: InChI=1S/C8H6N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)(H,11,12)
InChIKey: BHXVYTQDWMQVBI-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference: 4498-67-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36-36/37/38
Safety Statements: 26-36/37/39-22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 56915
Product name: Indazole-3-carboxylic acid
Purity: ≥97.0% (HPLC)
Packaging: 10g
Price: $138
Updated: 2023/06/20

Sigma-Aldrich

Product number: 56915
Product name: Indazole-3-carboxylic acid
Purity: ≥97.0% (HPLC)
Packaging: 50g
Price: $468
Updated: 2023/06/20

TCI Chemical

Product number: I0672
Product name: Indazole-3-carboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $21
Updated: 2024/03/01

TCI Chemical

Product number: I0672
Product name: Indazole-3-carboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $57
Updated: 2024/03/01

Alfa Aesar

Product number: H64001
Product name: 1H-Indazole-3-carboxylic acid, 98%
Packaging: 5g
Price: $29.65
Updated: 2024/03/01

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7-Hydroxygranisetron Chemical Properties,Usage,Production

Chemical Properties

yellow crystal

Uses

Indazole-3-carboxylic acid may be used in the synthesis of the following:

N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
1H-indazole-3-carboxamide

Uses

Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251

7-Hydroxygranisetron Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Isatin Stannous chloride Sodium nitrite Hydrochloric acid Acetic acid Sodium hydroxide Sulfuric acid

Preparation Products

3-Methylindole Lonidamine

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7-Hydroxygranisetron Suppliers

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View Lastest Price from 7-Hydroxygranisetron manufacturers

Dorne Chemical Technology co. LTD

Product: 7-Hydroxygranisetron 4498-67-3
Price: US $1.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-03-26

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 7-Hydroxygranisetron 4498-67-3
Price: US $500.00-300.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-23

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Indazole-3-carboxylic acid 4498-67-3
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-28

4498-67-3, 7-HydroxygranisetronRelated Search:

Calconcarboxylic acid Citric acid Folic acid 1-Methylindazole-3-carboxylic acid Ethyl 2-(Chlorosulfonyl)acetate 1H-INDAZOLE-4-CARBOXYLIC ACID Indazole Indazole-4-boronic acid, hydrochloride 1H-INDAZOLE-5-BORONIC ACID 6-INDAZOLYBORONIC ACID Indometacin INDOMETHACIN SODIUM 7-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Methyl indole-6-carboxylate 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE 6-Hydroxyindole Indole-4-carboxylic acid Ascoric Acid

1H-INDAZOL-3-CARBONIC ACID

1H-INDAZOLE-3-CARBOXYLIC ACID

1H-INDAZOLE-3-CARBONIC ACID

AKOS BB-9978

3-INDAZOLECARBOXYLIC ACID

3-CARBOXYINDAZOLE

ndazole-3-carboxylic acid

INDAZOLE-3-CARBOXYLIC ACID

3-Carboxy-1H-indazole

Granisetron Impurity 8（Granisetron EP Impurity H）

3(1H)-Indazolecarboxylic Acid

NSC 520610

INDAPAMIDE

Indazole-3-carboxylic acid ,98%

Indazole-3-carboxylic acid,97%

1H-Indazole-3-carboxylic ...

Indazole-3-carboxylic acid 1H-Indazole-3-carboxylic acid

Indazole-3-carboxylic acid >=97.0% (HPLC)

Granisetron EP impurity H

Benzopyrazole-3-carboxylic acid

Indazole-3-carboxylicAcid&gt

7-Hydroxygranisetron ISO 9001：2015 REACH

Indazole - 3 - carbo

Indazole-3-carboxylicaci

Content of indazole -3- carboxylic acid

Indazole-3-carboxylic acid (7CI)

Granisetron Hydrochloride EP Impurity H

Granisetron Hydrochloride Impurity H

Granisetron Impurity HCl

4498-67-3

581083-36-9

498-67-3

C8H6N2O2

Heterocyclic Building Blocks

Indazoles

Building Blocks

Indoles and derivatives

pharmacetical

Carboxylic Acids

Organic acids

Acids and Derivatives

Heterocycles

(intermediate of granisetron)

Indazoles

Indole Derivatives

Carboxylic Acids

Fused Ring Systems

Building Blocks

Heterocyclic Building Blocks

PHARMACEUTICAL INTERMEDIATES