ChemicalBook > CAS DataBase List > 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-

1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-

Product Name: 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-
CAS No.: 663171-32-2
Chemical Name: 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-
Synonyms: Biotin-PEG4-NH2;(+)-BIOTIN-PEG4-AMINE;(+)-Biotin-PEG4-CH2CH2NH2;(+)-Biotin-PEG₄-amine;N-Biotinyl-3,6,9,12-tetraoxatetradecane-1,14-diamine;N-[2-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide;N-(17-amino-3,6,9,12,15-pentaoxaheptadecyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;(3aS,4S,6aR)-N-(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-
CBNumber: CB82470861
Molecular Formula: C20H38N4O6S
Formula Weight: 462.6
MOL File: 663171-32-2.mol

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1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Property

Boiling point:: 724.4±60.0 °C(Predicted)
Density: 1.161±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DCM, Ethanol
pka: 13.90±0.40(Predicted)
form: powder to lump
color: White to Almost white
InChIKey: GVGZXRGPGZMYTB-LNLFQRSKSA-N
SMILES: C1(=O)N[C@]2([H])[C@H](CCCCC(NCCOCCOCCOCCOCCN)=O)SC[C@]2([H])N1

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5560
Product name: Biotin-PEG4-Amine
Purity: >94.0%(HPLC)
Packaging: 10mg
Price: $99
Updated: 2025/07/31

TCI Chemical

Product number: B6689
Product name: Biotin-PEG4-Amine (2mg×5)
Packaging: 1SET
Price: $252
Updated: 2025/07/31

TCI Chemical

Product number: B5560
Product name: Biotin-PEG4-Amine
Purity: >94.0%(HPLC)
Packaging: 50mg
Price: $293
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FB72901
Product name: Biotin-PEG4-amine
Packaging: 50mg
Price: $115
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB72901
Product name: Biotin-PEG4-amine
Packaging: 100mg
Price: $200
Updated: 2021/12/16

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1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Chemical Properties,Usage,Production

Description

Biotin-PEG4-amine is a popular biotinylation reagent with PEG spacer. It can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. PEG spacer increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Uses

Biotin-PEG4-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Suppliers

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View Lastest Price from 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG4-amine 663171-32-2
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-30

663171-32-2, 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-Related Search:

H2N-PEG24-tBu Boc-1-amino-3,6-dioxa-8-octanediamine 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG3-CH2COOH 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Biotin-PEG5-SH Biotin-PEG5-Amine Biotin-PEG5-azide N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE Biotin-PEG4-N3 Biotin-PEG<sub>4</sub>-Azide N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Biotin-PEG3-N3 Biotin-PEG4- Picolyl Azide Biotin-PEG4-Amide-C6-Azide Biotin-PEG4-Mal Biotin-PEG4-PFP ester

1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)-

(3aS,4S,6aR)-N-(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide

(+)-BIOTIN-PEG4-AMINE

(+)-Biotin-PEG<sub>4</sub>-amine

N-(17-amino-3,6,9,12,15-pentaoxaheptadecyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

N-(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide

(+)-Biotin-PEG4-CH2CH2NH2

Biotin-PEG4-NH2

N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]pentanamide

N-[2-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide

N-Biotinyl-3,6,9,12-tetraoxatetradecane-1,14-diamine

Biotin-PEG4-CH2CH2NH2/1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-, (3aS,4S,6aR)-

663171-32-2

C20H38N4O6S

peg