Biotin-PEG2-azide
- Product Name
- Biotin-PEG2-azide
- CAS No.
- 1910803-72-3
- Chemical Name
- Biotin-PEG2-azide
- Synonyms
- Biotin-PEG?-N?;BITOIN-PEG2-AZIDE;Biotin-PEG2-azide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-
- CBNumber
- CB82546797
- Molecular Formula
- C16H28N6O4S
- Formula Weight
- 400.5
- MOL File
- 1910803-72-3.mol
Biotin-PEG2-azide Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- soluble in DMF, DMSO, moderately soluble in water
- form
- Solid
- color
- White to off-white
- Appearance
- light beige solid
N-Bromosuccinimide Price
- Product number
- BP-22118
- Product name
- Biotin-PEG2-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- 271604
- Product name
- Biotin-PEG2-azide
- Packaging
- 500mg
- Price
- $610
- Updated
- 2021/12/16
- Product number
- 271604
- Product name
- Biotin-PEG2-azide
- Packaging
- 1g
- Price
- $896
- Updated
- 2021/12/16
- Product number
- SC-50081
- Product name
- Biotin-PEG2-azide
- Purity
- 95%
- Packaging
- 500mg
- Price
- $610
- Updated
- 2021/12/16
Biotin-PEG2-azide Chemical Properties,Usage,Production
Description
Biotin-PEG2-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
Uses
Biotin-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
Biotin-PEG2-azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Biotin-PEG2-azide manufacturers
- Product
- Biotin-PEG2-azide 1910803-72-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21