Amorolfine hydrochloride

Product Name: Amorolfine hydrochloride
CAS No.: 78613-38-4
Chemical Name: Amorolfine hydrochloride
Synonyms: Odenil;Locetar;Curanail;Amorolfine HCI;AMOROLFINE HCL;Ro 14-4767/002;Amorolfine hydrochloride;Amorolfine Hydrochloride >Amorolfine hydrochloride CRS;Amorolfine hydrochloride, >=99%
CBNumber: CB8262394
Molecular Formula: C21H36ClNO
Formula Weight: 353.98
MOL File: 78613-38-4.mol

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Amorolfine hydrochloride Property

Boiling point:: 120 C
storage temp.: room temp
solubility: DMSO: ≥5mg/mL (warmed)
form: powder
color: white to beige
InChIKey: XZKWIPVTHGWDCF-KUZYQSSXSA-N
CAS DataBase Reference: 78613-38-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 20/21/22-36/37/38-50/53-38-22
Safety Statements: 26-36-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
HS Code: 29411010

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H411Toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0283
Product name: Amorolfine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0283
Product name: Amorolfine hydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $429
Updated: 2024/03/01

TCI Chemical

Product number: A2161
Product name: Amorolfine Hydrochloride
Purity: >98.0%(T)
Packaging: 1g
Price: $238
Updated: 2024/03/01

TCI Chemical

Product number: A2161
Product name: Amorolfine Hydrochloride
Purity: >98.0%(T)
Packaging: 200mg
Price: $79
Updated: 2024/03/01

Cayman Chemical

Product number: 26077
Product name: Amorolfine (hydrochloride)
Purity: ≥98%
Packaging: 100mg
Price: $62
Updated: 2024/03/01

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Amorolfine hydrochloride Chemical Properties,Usage,Production

Description

Amorolfine hydrochloride is the first morpholine antifungal agent useful in the topical treatment of onychomycosis. Mechanistically, it appears to inhibit two stages of the ergosterol biosynthetic pathway, which is necessary for fungal cell viability. Active against a broad spectrum of fungi, amorolfiie hydrochloride is particularly effective against yeasts such as Histoplasma capsulatum, dermatophytes and dematiaceous fungi.

Chemical Properties

Liquid

Originator

Roche (Switzerland)

Uses

Amorolfine hydrochloride has been used as an antifungal agent.

Uses

antihypertensive

Definition

ChEBI: A hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta14 reductase and D7-D8 isomerase and an antifungal ag nt, it is used for the topical treatment of fungal nail and skin infections.

brand name

Loceryl (Hoffmann-LaRoche).

Biochem/physiol Actions

Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.

Amorolfine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Amorolfine hydrochloride Suppliers

Americas 1 Brazil 1 Canada 2 China 265 Europe 2 France 3 Germany 2 India 32 Japan 1 Nepal 1 Poland 1 South Korea 1 Spain 1 Switzerland 2 United Kingdom 6 United States 28 Global 349

Xiamen Halosyntech Co., Ltd

Tel: 0592-6688068 18106901346
Fax: 0592-6686768
Email: qbl2015@halolife.cn
Country: China
ProdList: 94
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169097
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7639
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

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View Lastest Price from Amorolfine hydrochloride manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Amorolfine hydrochloride 78613-38-4
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-24

Hebei Xinsheng New Material Technology Co., LTD.

Product: Amorolfine hydrochloride 78613-38-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-09-04

Firsky International Trade (Wuhan) Co., Ltd

Product: Amorolfine hydrochloride 78613-38-4
Price: US $30.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2023-10-09

78613-38-4, Amorolfine hydrochlorideRelated Search:

Moroxydine hydrochloride Moroxydine Amorolfine hydrochloride 1-AdaMantanethylaMine ISOPROPYLHYDRAZINE HYDROCHLORIDE Amorolfine Topotecan hydrochloride Tridemorph Dimethomorph Hydroxylamine hydrochloride Tramadol hydrochloride cis-2,6-Dimethylmorpholine Dimethylmorpholine Sibutramine hydrochloride N-[2-(acetyloxy)propyl]-N-[3-[4-(1,1-diMethylpropyl)phenyl]-2-Methylpropyl]-forMaMide Amorolfine Impurity 6 Amorolfine Impurity 11 4-[3-[4-(1,1-diMethylpropyl)-phenyl]-2-Methylpropyl]-2,6-diMethylMorpholine 4-oxide

AMOROLFINE HCL

Amorolfine HCI

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, (2R,6S)-rel-

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, cis-

Ro 14-4767/002

(+/-)-cis-2,6-Dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride

Amorolfine hydrochloride

(2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, hydrochloride (1:1)

(2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride

Amorolfine hydrochloride, >=99%

AMOROLFIN; CURANAIL; LOCERYL; LOCETAR; ODENIL

Curanail

Locetar

Odenil

2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride

Amorolfine for system suitability

(2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

Amorolfine Hydrochloride &gt

Amorolfine for system suitability CRS

Amorolfine hydrochloride CRS

cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride

2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine

(2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

Amorolfine hydrochloride USP/EP/BP

Amorolfine HCl (Ro 14-4767/002)

Amorolfine HydrochlorideQ: What is Amorolfine Hydrochloride Q: What is the CAS Number of Amorolfine Hydrochloride Q: What is the storage condition of Amorolfine Hydrochloride Q: What are the applications of Amorolfine Hydrochloride

rel-(2R,6S)-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride (Amorolfine Impurity)

(2S,6R)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

78613-38-4

78163-38-4

C21H35ONHCl

HYTRIN

Antifungal (Topical)

Antifungals for Research and Experimental Use

Biochemistry

78613-38-4