Amorolfine
Uses Side effects- Product Name
- Amorolfine
- CAS No.
- 67467-83-8
- Chemical Name
- Amorolfine
- Synonyms
- Amorofen;Amorophen;AMOROLFINE;Amorolfine Impurity 19;Amorolfine Impurity 22;Voriconazole Impurity 97;(2R,6S)-4-[3-(4-tert-amylphenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine;cis-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine;(2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;Amorolfine/4-[3-[4-(11-Dimethylpropyl)phenyl]-2-methylpropyl]-26-dimethylmorpholine
- CBNumber
- CB92130223
- Molecular Formula
- C21H35NO
- Formula Weight
- 317.51
- MOL File
- 67467-83-8.mol
Amorolfine Property
- Boiling point:
- 407.1±33.0 °C(Predicted)
- Density
- 0.924±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 7.33±0.10(Predicted)
- color
- Colourless
Amorolfine Chemical Properties,Usage,Production
Uses
Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the USA for such indications. The major advantage of this new antimycotic drug presumably lies in its potential for use as 5% nail lacquer in the treatment of onychomycosis caused by dermatophytes and Candida spp.
Side effects
Topical application of amorolfine (5% nail lacquer and 0.25% cream) is generally well tolerated, with up to 5% of patients reporting minor symptoms. In patients using the nail lacquer, these events included burning, itching, redness, and local pain, which were toleratable and confined to the application site. Adverse effects of scaling, weeping, blistering, and edema have also been described for the cream formulation.
Uses
Antimycotic.
Uses
Amorolfine is a novel antifungal agent used in the treatment of cutaneous fungal disease.
brand name
Loceryl (Hoffmann-LaRoche).
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View Lastest Price from Amorolfine manufacturers
- Product
- Amorolfine 67467-83-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19
- Product
- AMorolfine 67467-83-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- AMorolfine 67467-83-8
- Price
- US $32.00/KG
- Min. Order
- 1KG
- Purity
- 99%，HPLC
- Supply Ability
- 100kg
- Release date
- 2020-09-10