Amorolfine

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Uses Side effects

Product Name: Amorolfine
CAS No.: 67467-83-8
Chemical Name: Amorolfine
Synonyms: Amorofen;AMOROLFINE;Amorolfine Impurity 19;Amorolfine Impurity 22;Voriconazole Impurity 97;(2R,6S)-4-[3-(4-tert-amylphenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine;cis-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine;(2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;Amorolfine/4-[3-[4-(11-Dimethylpropyl)phenyl]-2-methylpropyl]-26-dimethylmorpholine
CBNumber: CB92130223
Molecular Formula: C21H35NO
Formula Weight: 317.51
MOL File: 67467-83-8.mol

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Amorolfine Property

Boiling point:: 407.1±33.0 °C(Predicted)
Density: 0.924±0.06 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
pka: 7.33±0.10(Predicted)
color: Colourless

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Hazard and Precautionary Statements (GHS)

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Amorolfine Chemical Properties,Usage,Production

Uses

Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the USA for such indications. The major advantage of this new antimycotic drug presumably lies in its potential for use as 5% nail lacquer in the treatment of onychomycosis caused by dermatophytes and Candida spp.

Side effects

Topical application of amorolfine (5% nail lacquer and 0.25% cream) is generally well tolerated, with up to 5% of patients reporting minor symptoms. In patients using the nail lacquer, these events included burning, itching, redness, and local pain, which were toleratable and confined to the application site. Adverse effects of scaling, weeping, blistering, and edema have also been described for the cream formulation.

Uses

Antimycotic.

Uses

Amorolfine is a novel antifungal agent used in the treatment of cutaneous fungal disease.

brand name

Loceryl (Hoffmann-LaRoche).

Amorolfine Preparation Products And Raw materials

Raw materials

Preparation Products

Amorolfine

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View Lastest Price from Amorolfine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Amorolfine 67467-83-8
Price: US $0.01-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50 tons
Release date: 2020-05-12

Dideu Industries Group Limited

Product: Amorolfine 67467-83-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: AMorolfine 67467-83-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

67467-83-8, AmorolfineRelated Search:

Dimethomorph Itraconazole Ciclopirox ethanolamine Ciclopirox Terbinafine hydrochloride Amorolfine Hydrochloride Chlorodimethylphenylsilane Moroxydine Moroxydine hydrochloride PHENYL VALERATE Tridemorph Phenylacetic acid Amorolfine Amorolfine flumorph

AMOROLFINE

cis-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine

(2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine

(2R,6S)-4-[3-(4-tert-amylphenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine

Amorolfine/4-[3-[4-(11-Dimethylpropyl)phenyl]-2-methylpropyl]-26-dimethylmorpholine

Amorolfine Impurity 22

Voriconazole Impurity 97

Amorofen

Amorolfine Impurity 19

67467-83-8

8613-38-4